PE anti-mouse TLR4 (CD284)/MD2 Complex | BioLegend 117606 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse TLR4 (CD284)/MD2 Complex

catalog :

117606

quantity :

200 μg

price :

414 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

MTS510

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 3	Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T. Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses. J Immunol. 2015;194:5426-36 pubmed publisher
	Raychowdhury R, Gentili M, Cui A, Schweitzer L, Li B, Hacohen N. Macrophages from Rosa26-Integrated Cas9-Expressing C57BL/6J Mice Have a Putative TRIF-Mediated Defect in the TLR-3/4 Signaling. Immunohorizons. 2021;5:818-829 pubmed publisher
	Cong L, Maishi N, Annan D, Young M, Morimoto H, Morimoto M, et al. Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy. Breast Cancer Res. 2021;23:51 pubmed publisher
	Takayanagi Y, Kikuchi T, Hasegawa Y, Naiki Y, Goto H, Okada K, et al. Porphyromonas gingivalis Mfa1 Induces Chemokine and Cell Adhesion Molecules in Mouse Gingival Fibroblasts via Toll-Like Receptors. J Clin Med. 2020;9: pubmed publisher
	Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
	Lim T, Bunjamin M, Ruedl C, Su I. Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling. J Exp Med. 2020;217: pubmed publisher
	Poznanski S, Nham T, Chew M, Lee A, Hammill J, Fan I, et al. Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model. Cancer Immunol Res. 2018;6:1174-1185 pubmed publisher
	Wu M, Singh A. Microfluidic molecular assay platform for the detection of miRNAs, mRNAs, proteins, and posttranslational modifications at single-cell resolution. J Lab Autom. 2014;19:587-92 pubmed publisher
	Tanigawa T, Morikawa A, Hayashi K, Dan K, Tsuchihashi N, Goto F, et al. Auditory cells produce nitric oxide in response to bacterial lipopolysaccharide. Innate Immun. 2013;19:115-20 pubmed publisher
	Souza Fonseca Guimaraes F, Parlato M, Fitting C, Cavaillon J, Adib Conquy M. NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis. J Immunol. 2012;188:5850-8 pubmed publisher
	Laplante P, Amireault P, Subang R, Dieudé M, Levine J, Rauch J. Interaction of ?2-glycoprotein I with lipopolysaccharide leads to Toll-like receptor 4 (TLR4)-dependent activation of macrophages. J Biol Chem. 2011;286:42494-503 pubmed publisher
	Kanada S, Nishiyama C, Nakano N, Suzuki R, Maeda K, Hara M, et al. Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells. Blood. 2011;117:2211-22 pubmed publisher
	Nalbandian G, Paharkova Vatchkova V, Mao A, Nale S, Kovats S. The selective estrogen receptor modulators, tamoxifen and raloxifene, impair dendritic cell differentiation and activation. J Immunol. 2005;175:2666-75 pubmed

product information

Antigen :

TLR4 MD2 Complex

Apps. Abbrev. :

Cat # :

117606

Clone :

MTS510

Item :

PE anti-mouse TLR4 (CD284)/MD2 Complex

Isotype :

Rat IgG2a, κ

Other Names :

Toll-like Receptor 4/MD2 complex, TLR4-MD2-complex, TLR4/MD2, CD284/MD2

Size :

200 μg

Price (USD) :

414 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

Ba/F3 cell line transfected with mouse TLR4 /MD2 complex

Application Notes :

Anti-mouse TLR4 clones SA15-21 and MTS510 recognize distinct epitopes and don't cross block each other.^8 Clone MTS510 binds to an epitope of TLR4/MD-2 that is lost after LPS stimulation.^8 In addition to flow cytometric uses, the MTS510 antibody has also been used for immunoprecipitation, immunofluorescence, and blocking of LPS-induced stimulation. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 117607). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 117612) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage