product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-mouse CD11c
catalog :
117324
quantity :
100 μg
price :
265 USD
clonality :
monoclonal
host :
hamsters
conjugate :
APC/Cy7
clone name :
N418
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 53
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s2a
Shikama Y, Kurosawa M, Furukawa M, Ishimaru N, Matsushita K. Involvement of adiponectin in age-related increases in tear production in mice. Aging (Albany NY). 2019;11:8329-8346 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Mogilenko D, Haas J, L homme L, Fleury S, Quemener S, Levavasseur M, et al. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019;177:1201-1216.e19 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4b
Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; fig 4a, 5c, 6b
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
  • flow cytometry; mouse; fig s13b
Lau A, Chung H, Komada T, Platnich J, Sandall C, Choudhury S, et al. Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury. J Clin Invest. 2018;128:2894-2913 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Trapecar M, Khan S, Cohn B, Wu F, Sanjabi S. B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunol. 2018;11:1158-1167 pubmed publisher
  • flow cytometry; mouse; 1:200; tbl 1
Jackson Jones L, Duncan S, Magalhaes M, Campbell S, Maizels R, McSorley H, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Herz J, Johnson K, McGavern D. Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells. J Exp Med. 2015;212:1153-69 pubmed publisher
  • flow cytometry; mouse; fig 4
Navarathna D, Stein E, Lessey Morillon E, Nayak D, Martin Manso G, Roberts D. CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis. PLoS ONE. 2015;10:e0128220 pubmed publisher
  • flow cytometry; mouse; fig 1
Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed publisher
  • flow cytometry; mouse
Kaiser P, Regoes R, Dolowschiak T, Wotzka S, Lengefeld J, Slack E, et al. Cecum lymph node dendritic cells harbor slow-growing bacteria phenotypically tolerant to antibiotic treatment. PLoS Biol. 2014;12:e1001793 pubmed publisher
Choi H, Deng J, Li S, Silk T, Dong L, Brea E, et al. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Rep. 2019;27:806-819.e5 pubmed publisher
Galle Treger L, Sankaranarayanan I, Hurrell B, Howard E, Lo R, Maazi H, et al. Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes. Nat Commun. 2019;10:713 pubmed publisher
White J, Xiong S, Malvin N, Khoury Hanold W, Heuckeroth R, Stappenbeck T, et al. Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses. Cell. 2018;175:1198-1212.e12 pubmed publisher
Proto J, Doran A, Gusarova G, Yurdagul A, Sozen E, Subramanian M, et al. Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Immunity. 2018;49:666-677.e6 pubmed publisher
Wang T, Fan C, Yao A, Xu X, Zheng G, You Y, et al. The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells. Immunity. 2018;49:504-514.e4 pubmed publisher
Lino A, Dang V, Lampropoulou V, Welle A, Joedicke J, Pohar J, et al. LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018;49:120-133.e9 pubmed publisher
Trompette A, Gollwitzer E, Pattaroni C, Lopez Mejia I, Riva E, Pernot J, et al. Dietary Fiber Confers Protection against Flu by Shaping Ly6c- Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism. Immunity. 2018;48:992-1005.e8 pubmed publisher
Echevarría Vargas I, Reyes Uribe P, Guterres A, Yin X, Kossenkov A, Liu Q, et al. Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma. EMBO Mol Med. 2018;10: pubmed publisher
Draijer C, Robbe P, Boorsma C, Hylkema M, Melgert B. Dual role of YM1+ M2 macrophages in allergic lung inflammation. Sci Rep. 2018;8:5105 pubmed publisher
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki L, Lv X, et al. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018;128:1283-1299 pubmed publisher
Hayatsu N, Miyao T, Tachibana M, Murakami R, Kimura A, Kato T, et al. Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells. Immunity. 2017;47:268-283.e9 pubmed publisher
Lee H, Zhang D, Wu J, Otterbein L, Jin Y. Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin ?1 Recycling. J Immunol. 2017;199:1453-1464 pubmed publisher
Clement M, Marsden M, Stacey M, Abdul Karim J, Gimeno Brias S, Costa Bento D, et al. Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence. PLoS Pathog. 2016;12:e1006050 pubmed publisher
Khan S, Woodruff E, Trapecar M, Fontaine K, Ezaki A, Borbet T, et al. Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication. J Exp Med. 2016;213:2913-2929 pubmed
Galle Treger L, Suzuki Y, Patel N, Sankaranarayanan I, Aron J, Maazi H, et al. Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity. Nat Commun. 2016;7:13202 pubmed publisher
Yoshioka D, Kajiwara C, Ishii Y, Umeki K, Hiramatsu K, Kadota J, et al. Efficacy of ?-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. Antimicrob Agents Chemother. 2016;60:6146-54 pubmed publisher
Ariyoshi Y, Watanabe M, Eikawa S, Yamazaki C, Sadahira T, Hirata T, et al. The induction of antigen-specific CTL by in situ Ad-REIC gene therapy. Gene Ther. 2016;23:408-14 pubmed publisher
Shon W, Lee Y, Shin J, Choi E, Shin D. Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks. Sci Rep. 2015;5:17305 pubmed publisher
Furuya Y, Furuya A, Roberts S, Sanfilippo A, Salmon S, Metzger D. Prevention of Influenza Virus-Induced Immunopathology by TGF-β Produced during Allergic Asthma. PLoS Pathog. 2015;11:e1005180 pubmed publisher
Calderon B, Carrero J, Ferris S, Sojka D, Moore L, Epelman S, et al. The pancreas anatomy conditions the origin and properties of resident macrophages. J Exp Med. 2015;212:1497-512 pubmed publisher
Koyama M, Cheong M, Markey K, Gartlan K, Kuns R, Locke K, et al. Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease. J Exp Med. 2015;212:1303-21 pubmed publisher
Rodrigues Viana C, Castro P, Marques S, Paz Lopes M, Gonçalves R, Campos P, et al. Differential Contribution of Acute and Chronic Inflammation to the Development of Murine Mammary 4T1 Tumors. PLoS ONE. 2015;10:e0130809 pubmed publisher
Sasaki Y, Ohta M, Desai D, Figueiredo J, Whelan M, Sugano T, et al. Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance. PLoS ONE. 2015;10:e0131176 pubmed publisher
Kim P, Xia Juan X, Crump K, Abe T, Hajishengallis G, Sahingur S. Toll-Like Receptor 9-Mediated Inflammation Triggers Alveolar Bone Loss in Experimental Murine Periodontitis. Infect Immun. 2015;83:2992-3002 pubmed publisher
Metzger D, Furuya Y, Salmon S, Roberts S, Sun K. Limited Efficacy of Antibacterial Vaccination Against Secondary Serotype 3 Pneumococcal Pneumonia Following Influenza Infection. J Infect Dis. 2015;212:445-52 pubmed publisher
Davis M, Eastman A, Qiu Y, Gregorka B, Kozel T, Osterholzer J, et al. Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence. J Immunol. 2015;194:2219-31 pubmed publisher
Ballet R, Emre Y, Jemelin S, Charmoy M, Tacchini Cottier F, Imhof B. Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major. PLoS Pathog. 2014;10:e1004550 pubmed publisher
Zhang K, Dupont A, Torow N, Gohde F, Gohde F, Leschner S, et al. Age-dependent enterocyte invasion and microcolony formation by Salmonella. PLoS Pathog. 2014;10:e1004385 pubmed publisher
Leppin K, Behrendt A, Reichard M, Stachs O, Guthoff R, Baltrusch S, et al. Diabetes mellitus leads to accumulation of dendritic cells and nerve fiber damage of the subbasal nerve plexus in the cornea. Invest Ophthalmol Vis Sci. 2014;55:3603-15 pubmed publisher
Choi J, Cheong T, Ha N, Ko Y, Cho C, Jeon J, et al. Orientia tsutsugamushi subverts dendritic cell functions by escaping from autophagy and impairing their migration. PLoS Negl Trop Dis. 2013;7:e1981 pubmed publisher
Sasaki I, Hoshino K, Sugiyama T, Yamazaki C, Yano T, Iizuka A, et al. Spi-B is critical for plasmacytoid dendritic cell function and development. Blood. 2012;120:4733-43 pubmed publisher
Eisenach P, Roghi C, Fogarasi M, Murphy G, English W. MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 2010;123:4182-93 pubmed publisher
Bankoti J, Burnett A, Navarro S, Miller A, Rase B, Shepherd D. Effects of TCDD on the fate of naive dendritic cells. Toxicol Sci. 2010;115:422-34 pubmed publisher
Osterholzer J, Chen G, Olszewski M, Curtis J, Huffnagle G, Toews G. Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes. J Immunol. 2009;183:8044-53 pubmed publisher
Fahlén Yrlid L, Gustafsson T, Westlund J, Holmberg A, Strömbeck A, Blomquist M, et al. CD11c(high )dendritic cells are essential for activation of CD4+ T cells and generation of specific antibodies following mucosal immunization. J Immunol. 2009;183:5032-41 pubmed publisher
You Y, Zhao H, Wang Y, Carter R. Cutting edge: Primary and secondary effects of CD19 deficiency on cells of the marginal zone. J Immunol. 2009;182:7343-7 pubmed publisher
Randall L, Amante F, McSweeney K, Zhou Y, Stanley A, Haque A, et al. Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities. Infect Immun. 2008;76:3312-20 pubmed publisher
Pericolini E, Cenci E, Gabrielli E, Perito S, Mosci P, Bistoni F, et al. Indinavir influences biological function of dendritic cells and stimulates antifungal immunity. J Leukoc Biol. 2008;83:1286-94 pubmed publisher
Benson M, Pino Lagos K, Rosemblatt M, Noelle R. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med. 2007;204:1765-74 pubmed
Turnquist H, Raimondi G, Zahorchak A, Fischer R, Wang Z, Thomson A. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. J Immunol. 2007;178:7018-31 pubmed
Cervantes Barragan L, Zust R, Weber F, Spiegel M, Lang K, Akira S, et al. Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood. 2007;109:1131-7 pubmed
Wikstrom M, Batanero E, Smith M, Thomas J, von Garnier C, Holt P, et al. Influence of mucosal adjuvants on antigen passage and CD4+ T cell activation during the primary response to airborne allergen. J Immunol. 2006;177:913-24 pubmed
product information
Antigen :
CD11c
Apps. Abbrev. :
Flow Cytometry
Cat # :
117324
Clone :
N418
Item :
APC/Cyanine7 anti-mouse CD11c
Isotype :
Armenian Hamster IgG
Other Names :
αX integrin, integrin αX chain, CR4, p150, ITGAX
Size :
100 μg
Price (USD) :
265 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
APC_CYANINE7
Immunogen :
Mouse spleen dendritic cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 3 , immunohistochemical staining of acetone-fixed frozen sections 3 , and immunofluorescence microscopy 5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections 10 ).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA