product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse CD11c
catalog :
117312
quantity :
100 μg
price :
215 USD
clonality :
monoclonal
host :
hamsters
conjugate :
AF647
clone name :
N418
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 139
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; loading ...
Liu H, Pedros C, Kong K, Canonigo Balancio A, Xue W, Altman A. Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy. J Immunother Cancer. 2021;9: pubmed publisher
  • flow cytometry; mouse; loading ...
Neumann S, Campbell K, Woodall M, Evans M, Clarkson A, Young S. Obesity Has a Systemic Effect on Immune Cells in Naïve and Cancer-Bearing Mice. Int J Mol Sci. 2021;22: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Cortés A, Solas M, Pejenaute A, Abellanas M, Garcia Lacarte M, Aymerich M, et al. Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice. Antioxidants (Basel). 2021;10: pubmed publisher
  • flow cytometry; mouse; 1:250; loading ...; fig 1f
Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed publisher
  • flow cytometry; mouse; fig 3
Forman R, Logunova L, Smith H, Wemyss K, Mair I, Boon L, et al. Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages. PLoS Pathog. 2021;17:e1009768 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 8b
Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed publisher
  • flow cytometry; mouse; fig 4b
Okunuki Y, Tabor S, Lee M, Connor K. CD47 Deficiency Ameliorates Ocular Autoimmune Inflammation. Front Immunol. 2021;12:680568 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Amoozgar Z, Kloepper J, Ren J, Tay R, Kazer S, Kiner E, et al. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021;12:2582 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 6b
Manrique Acevedo C, Padilla J, Naz H, Woodford M, Ghiarone T, Aroor A, et al. Mineralocorticoid Receptor in Myeloid Cells Mediates Angiotensin II-Induced Vascular Dysfunction in Female Mice. Front Physiol. 2021;12:588358 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Wang Y, Yang Y, Wang M, Wang S, Jeong J, Xu L, et al. Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production. Sci Transl Med. 2021;13: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
da Silva R, Elizondo D, Brandy N, Haddock N, Boddie T, de Oliveira L, et al. Leishmania donovani infection suppresses Allograft Inflammatory Factor-1 in monocytes and macrophages to inhibit inflammatory responses. Sci Rep. 2021;11:946 pubmed publisher
  • flow cytometry; mouse; 1:250; loading ...; fig s8a
Torretta S, Scagliola A, Ricci L, Mainini F, Di Marco S, Cuccovillo I, et al. D-mannose suppresses macrophage IL-1β production. Nat Commun. 2020;11:6343 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Jensen I, Jensen S, Sjaastad F, Gibson Corley K, Dileepan T, Griffith T, et al. Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Xu A, Barbosa R, Calado D. Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 6h
Fernandes R, Li C, Wang G, Yang X, Savvides C, Glassman C, et al. Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 5q
Mezö C, Dokalis N, Mossad O, Staszewski O, Neuber J, Yilmaz B, et al. Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2020;8:119 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1s3, 4c
Manils J, Webb L, Howes A, Janzen J, Boeing S, Bowcock A, et al. CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Ning Y, Ding J, Sun X, Xie Y, Su M, Ma C, et al. HDAC9 deficiency promotes tumor progression by decreasing the CD8+ dendritic cell infiltration of the tumor microenvironment. J Immunother Cancer. 2020;8: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5d
Vacca F, Chauch C, Jamwal A, Hinchy E, Heieis G, Webster H, et al. A helminth-derived suppressor of ST2 blocks allergic responses. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3g
Zheng D, Gao F, Cheng Q, Bao P, Dong X, Fan J, et al. A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy. Nat Commun. 2020;11:1985 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b, 3e
Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, et al. Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice. World J Gastroenterol. 2020;26:918-932 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 2c
Wuggenig P, Kaya B, Melhem H, Ayata C, Hruz P, Sayan A, et al. Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice. Commun Biol. 2020;3:130 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Watanabe M, Kaneko Y, Ohishi Y, Kinoshita M, Sakairi T, Ikeuchi H, et al. Importance of methodology in the evaluation of renal mononuclear phagocytes and analysis of a model of experimental nephritis with Shp1 conditional knockout mice. Biochem Biophys Rep. 2020;22:100741 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Takai A, Kikuchi K, Ichimura M, Tsuneyama K, Moritoki Y, Matsumoto K, et al. Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis. BMC Gastroenterol. 2020;20:46 pubmed publisher
  • flow cytometry; mouse; 2.5 ug/ml; loading ...
Wang J, Li P, Yu Y, Fu Y, Jiang H, Lu M, et al. Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science. 2020;367: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Forbester J, Clement M, Wellington D, Yeung A, Dimonte S, Marsden M, et al. IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models. J Virol. 2020;94: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6s2
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s16d
Schafflick D, Xu C, Hartlehnert M, Cole M, Schulte Mecklenbeck A, Lautwein T, et al. Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis. Nat Commun. 2020;11:247 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Khorooshi R, Marczynska J, Dieu R, Wais V, Hansen C, Kavan S, et al. Innate signaling within the central nervous system recruits protective neutrophils. Acta Neuropathol Commun. 2020;8:2 pubmed publisher
  • flow cytometry; mouse; fig 2c
Williford J, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell T, et al. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019;5:eaay1357 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4, s1
Eastman A, Xu J, Bermik J, Potchen N, den Dekker A, Neal L, et al. Epigenetic stabilization of DC and DC precursor classical activation by TNFα contributes to protective T cell polarization. Sci Adv. 2019;5:eaaw9051 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Mantani P, Dunér P, Ljungcrantz I, Nilsson J, Bjorkbacka H, Fredrikson G. ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions. BMC Immunol. 2019;20:47 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Shikama Y, Kurosawa M, Furukawa M, Ishimaru N, Matsushita K. Involvement of adiponectin in age-related increases in tear production in mice. Aging (Albany NY). 2019;11:8329-8346 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2s2a
Carpentier K, Davenport B, HAIST K, McCarthy M, May N, Robison A, et al. Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3b
Simmons S, Sasaki N, Umemoto E, Uchida Y, Fukuhara S, Kitazawa Y, et al. High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig e10
Majer O, Liu B, Kreuk L, Krogan N, Barton G. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature. 2019;575:366-370 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e6b
Solis A, Bielecki P, Steach H, Sharma L, Harman C, Yun S, et al. Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity. Nature. 2019;573:69-74 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2b
Ma L, Dichwalkar T, Chang J, Cossette B, Garafola D, Zhang A, et al. Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science. 2019;365:162-168 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4c
Wirsching H, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino P, et al. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019;4: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1f
Loh J, Xu S, Huo J, Kim S, Wang Y, Lam K. Dok3-protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity. J Clin Invest. 2019;129:2717-2729 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5b
Palacio L, Goyer M, Maggiorani D, Espinosa A, Villeneuve N, Bourbonnais S, et al. Restored immune cell functions upon clearance of senescence in the irradiated splenic environment. Aging Cell. 2019;18:e12971 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Di Pilato M, Kim E, Cadilha B, Prüßmann J, Nasrallah M, Seruggia D, et al. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. 2019;570:112-116 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5g
Sugiura D, Maruhashi T, Okazaki I, Shimizu K, Maeda T, Takemoto T, et al. Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses. Science. 2019;364:558-566 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1h
  • flow cytometry; mouse; 1:400; loading ...; fig ex1c
Hammerich L, Marron T, Upadhyay R, Svensson Arvelund J, Dhainaut M, Hussein S, et al. Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination. Nat Med. 2019;25:814-824 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s8b
Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, et al. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice. Nat Commun. 2019;10:1492 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4b
Kubli S, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, et al. AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. Proc Natl Acad Sci U S A. 2019;116:3604-3613 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 6s2
Lavoie S, Conway K, Lassen K, Jijon H, Pan H, Chun E, et al. The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Shishido T, Kohyama M, Nakai W, Matsumoto M, Miyata H, Suenaga T, et al. Invariant chain p41 mediates production of soluble MHC class II molecules. Biochem Biophys Res Commun. 2018;: pubmed publisher
  • flow cytometry; mouse; fig 3b
Ishizuka J, Manguso R, Cheruiyot C, Bi K, Panda A, Iracheta Vellve A, et al. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature. 2019;565:43-48 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; fig 4a, 5c, 6b
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s8a
Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5d
Hayashi T, Momota M, Kuroda E, Kusakabe T, Kobari S, Makisaka K, et al. DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination. Front Immunol. 2018;9:2619 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Wiedemann G, Aithal C, Kraechan A, Heise C, Cadilha B, Zhang J, et al. Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma. Transl Oncol. 2019;12:350-360 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1
Choi H, Suwanpradid J, Kim I, Staats H, Haniffa M, Macleod A, et al. Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles. Science. 2018;362: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5
Nicol M, Campbell G, Shaw D, Dransfield I, Ligertwood Y, Beard P, et al. Lack of IFNγ signaling attenuates spread of influenza A virus in vivo and leads to reduced pathogenesis. Virology. 2019;526:155-164 pubmed publisher
  • flow cytometry; mouse; fig 2e
Cabron A, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, et al. Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells. J Immunol. 2018;201:3106-3118 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Meyer I, Goetzke C, Kespohl M, Sauter M, Heuser A, Eckstein V, et al. Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis. Front Immunol. 2018;9:2303 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e7c
Wan X, Zinselmeyer B, Zakharov P, Vomund A, Taniguchi R, Santambrogio L, et al. Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. Nature. 2018;560:107-111 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed publisher
  • flow cytometry; mouse; fig s3b
Napolitano A, van der Veen A, Bunyan M, Borg A, Frith D, Howell S, et al. Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection. J Immunol. 2018;201:604-614 pubmed publisher
  • flow cytometry; mouse; fig s13b
Lau A, Chung H, Komada T, Platnich J, Sandall C, Choudhury S, et al. Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury. J Clin Invest. 2018;128:2894-2913 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3g
Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, et al. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med. 2018;24:814-822 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s5c
Huynh J, Lin C, Kimmey J, Jarjour N, Schwarzkopf E, Bradstreet T, et al. Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. J Exp Med. 2018;215:1823-1838 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Kyung D, Sung H, Kim Y, Kim K, Cho S, Choi J, et al. Global transcriptome analysis identifies weight regain-induced activation of adaptive immune responses in white adipose tissue of mice. Int J Obes (Lond). 2018;42:755-764 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
  • flow cytometry; mouse; 1:400; fig s1a
Chen W, Yang J, Wu Y, Li L, Li R, Chang Y, et al. IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury. Exp Mol Med. 2018;50:36 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s11
Foerster F, Boegel S, Heck R, Pickert G, R ssel N, Rosigkeit S, et al. Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells. Oncoimmunology. 2018;7:e1409929 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2c
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1d
Mencarelli A, Khameneh H, Fric J, Vacca M, El Daker S, Janela B, et al. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. Nat Commun. 2018;9:1102 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 1c
Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, et al. Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment. Oncotarget. 2018;9:11209-11226 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig s5b
Sun H, Lagarrigue F, Gingras A, Fan Z, Ley K, Ginsberg M. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018;217:1453-1465 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Sadana P, Geyer R, Pezoldt J, Helmsing S, Huehn J, Hust M, et al. The invasin D protein from Yersinia pseudotuberculosis selectively binds the Fab region of host antibodies and affects colonization of the intestine. J Biol Chem. 2018;293:8672-8690 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s8a
Chu L, Indramohan M, Ratsimandresy R, Gangopadhyay A, Morris E, Monack D, et al. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nat Commun. 2018;9:996 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s4a
Shakyawar D, Muralikrishna B, Radha V. C3G dynamically associates with nuclear speckles and regulates mRNA splicing. Mol Biol Cell. 2018;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Yang J, Cornelissen F, Papazian N, Reijmers R, Llorian M, Cupedo T, et al. IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes. J Exp Med. 2018;215:1069-1077 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Trapecar M, Khan S, Cohn B, Wu F, Sanjabi S. B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunol. 2018;11:1158-1167 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s4a
Zhu Y, Zhou J, Feng Y, Chen L, Zhang L, Yang F, et al. Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2. Front Immunol. 2018;9:87 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3b
King E, Mazor R, Cuburu N, Pastan I. Low-Dose Methotrexate Prevents Primary and Secondary Humoral Immune Responses and Induces Immune Tolerance to a Recombinant Immunotoxin. J Immunol. 2018;200:2038-2045 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5c
Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, et al. Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation. J Exp Med. 2018;215:481-500 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5a
Mazor R, King E, Onda M, Cuburu N, Addissie S, Crown D, et al. Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity. Proc Natl Acad Sci U S A. 2018;115:E733-E742 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Steiner D, Furuya Y, Metzger D. Detrimental Influence of Alveolar Macrophages on Protective Humoral Immunity during Francisella tularensis SchuS4 Pulmonary Infection. Infect Immun. 2018;86: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 9b
Lynch J, Werder R, Loh Z, Sikder M, Curren B, Zhang V, et al. Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. J Exp Med. 2018;215:537-557 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3a
Zhang Y, Khairallah C, Sheridan B, van der Velden A, Bliska J. CCR2+ Inflammatory Monocytes Are Recruited to Yersinia pseudotuberculosis Pyogranulomas and Dictate Adaptive Responses at the Expense of Innate Immunity during Oral Infection. Infect Immun. 2018;86: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Purvis H, Clarke F, Jordan C, Blanco C, Cornish G, Dai X, et al. Protein tyrosine phosphatase PTPN22 regulates IL-1β dependent Th17 responses by modulating dectin-1 signaling in mice. Eur J Immunol. 2018;48:306-315 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6a
Akiel M, Guo C, Li X, Rajasekaran D, Mendoza R, Robertson C, et al. IGFBP7 Deletion Promotes Hepatocellular Carcinoma. Cancer Res. 2017;77:4014-4025 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 8a
Lupfer C, Stokes K, Kuriakose T, Kanneganti T. Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance. J Virol. 2017;91: pubmed publisher
  • flow cytometry; mouse; fig 1d
Jinnohara T, Kanaya T, Hase K, Sakakibara S, Kato T, Tachibana N, et al. IL-22BP dictates characteristics of Peyer's patch follicle-associated epithelium for antigen uptake. J Exp Med. 2017;214:1607-1618 pubmed publisher
  • flow cytometry; mouse; fig 1a
Taylor S, Huang Y, Mallett G, Stathopoulou C, Felizardo T, Sun M, et al. PD-1 regulates KLRG1+ group 2 innate lymphoid cells. J Exp Med. 2017;214:1663-1678 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Kwan B, Zhu E, Tzeng A, Sugito H, Eltahir A, Ma B, et al. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. J Exp Med. 2017;214:1679-1690 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Kogo H, Shimizu M, Negishi Y, Uchida E, Takahashi H. Suppression of murine tumour growth through CD8+ cytotoxic T lymphocytes via activated DEC-205+ dendritic cells by sequential administration of ?-galactosylceramide in vivo. Immunology. 2017;151:324-339 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1b
Roufaiel M, Gracey E, Siu A, Zhu S, Lau A, Ibrahim H, et al. CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima. Nat Immunol. 2016;17:1263-1272 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1g
Schneider C, Nobs S, Heer A, Hirsch E, Penninger J, Siggs O, et al. Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection. J Leukoc Biol. 2017;101:367-376 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6e
  • flow cytometry; mouse; loading ...; fig 2b
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  • flow cytometry; mouse; loading ...; fig 3c
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product information
Antigen :
CD11c
Apps. Abbrev. :
Flow Cytometry, IHC, ICC, 3D IHC
Cat # :
117312
Clone :
N418
Item :
Alexa Fluor® 647 anti-mouse CD11c
Isotype :
Armenian Hamster IgG
Other Names :
αX integrin, integrin αX chain, CR4, p150, ITGAX
Size :
100 μg
Price (USD) :
215 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
A647
Immunogen :
Mouse spleen dendritic cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 3 , immunohistochemical staining of acetone-fixed frozen sections 3 , immunofluorescence microscopy 5, 9 (Alexa Fluor 488 conjugated N418 was used for IHC in frozen sections 10 ), and spatial biology (IBEX) 22,23 .
more info or order :
company information
BioLegend
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San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA