PE/Cyanine7 anti-mouse H-2Kb | BioLegend 116519 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-mouse H-2Kb

catalog :

116519

quantity :

25 μg

price :

141 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AF6-88.5

reactivity :

mouse

application :

flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s6b	Laffey K, Stiles R, Ludescher M, Davis T, Khwaja S, Bram R, et al. Early expression of mature αβ TCR in CD4-CD8- T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. Proc Natl Acad Sci U S A. 2022;119:e2118529119 pubmed publisher
blocking or activating experiments; mouse; fig 2d flow cytometry; mouse; loading ...; fig 2c	Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
	Aghayev T, Mazitova A, Fang J, Peshkova I, Rausch M, Hung M, et al. IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma. Cancer Discov. 2022;12:1960-1983 pubmed publisher
	Aggarwal N, Deerhake M, DiPalma D, Shahi S, Gaggioli M, Mangalam A, et al. Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease. Cell Rep. 2021;37:110170 pubmed publisher
	Boulch M, Cazaux M, Loe Mie Y, Thibaut R, Corre B, Lemaitre F, et al. A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity. Sci Immunol. 2021;6: pubmed publisher
	Williams J, Li S, Higgs E, Cabanov A, Wang X, Huang H, et al. Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells. Nat Commun. 2020;11:602 pubmed publisher
	Hafstrand I, Sayitoglu E, Apavaloaei A, Josey B, Sun R, Han X, et al. Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin. Proc Natl Acad Sci U S A. 2019;116:5055-5060 pubmed publisher
	Chaganty B, Qiu S, Gest A, Lu Y, Ivan C, Calin G, et al. Trastuzumab upregulates PD-L1 as a potential mechanism of trastuzumab resistance through engagement of immune effector cells and stimulation of IFN? secretion. Cancer Lett. 2018;430:47-56 pubmed publisher

product information

Antigen :

H-2Kb

Apps. Abbrev. :

Cat # :

116519

Clone :

AF6-88.5

Item :

PE/Cyanine7 anti-mouse H-2Kb

Isotype :

Mouse (BALB/c) IgG2a, κ

Other Names :

MHC class I

Size :

25 μg

Price (USD) :

141 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE7

Immunogen :

C57BL mouse splenocytes

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation^2 and immunohistochemical staining of acetone-fixed frozen sections^3. Clone AF6-88.5 is not suitable for immunohistochemical staining of formalin-fixed paraffin embedded sections.Does not cross-react with other haplotypes (e.g., d, f, j, k, p, q, r, s, u, v).;

more info or order :

BioLegend product webpage