product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-mouse H-2Kb
catalog :
116513
quantity :
25 μg
price :
112 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
AF6-88.5
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 8
Reference
Dong L, Chen C, Zhang Y, Guo P, Wang Z, Li J, et al. The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth. Cancer Cell. 2021;39:945-957.e10 pubmed publisher
Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, et al. Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance. Cell Metab. 2021;33:1221-1233.e11 pubmed publisher
Harsha Krovi S, Zhang J, Michaels Foster M, Brunetti T, Loh L, Scott Browne J, et al. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020;11:6238 pubmed publisher
Gurusamy D, Henning A, Yamamoto T, Yu Z, Zacharakis N, Krishna S, et al. Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies. Cancer Cell. 2020;37:818-833.e9 pubmed publisher
O Reilly L, Putoczki T, Mielke L, Low J, Lin A, Preaudet A, et al. Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner. Immunity. 2018;48:570-583.e8 pubmed publisher
Capuccini B, Lin J, Talavera López C, Khan S, Sodenkamp J, Spaccapelo R, et al. Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria. Sci Rep. 2016;6:39258 pubmed publisher
Chávez Santoscoy A, Roychoudhury R, Pohl N, Wannemuehler M, Narasimhan B, Ramer Tait A. Tailoring the immune response by targeting C-type lectin receptors on alveolar macrophages using "pathogen-like" amphiphilic polyanhydride nanoparticles. Biomaterials. 2012;33:4762-72 pubmed publisher
Norian L, Allen P. No intrinsic deficiencies in CD8+ T cell-mediated antitumor immunity with aging. J Immunol. 2004;173:835-44 pubmed
product information
Antigen :
H-2Kb
Apps. Abbrev. :
FC
Cat # :
116513
Clone :
AF6-88.5
Item :
Pacific Blue™ anti-mouse H-2Kb
Isotype :
Mouse (BALB/c) IgG2a, κ
Other Names :
MHC class I
Size :
25 μg
Price (USD) :
112 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Immunogen :
C57BL mouse splenocytes
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^2 and immunohistochemical staining of acetone-fixed frozen sections^3. Clone AF6-88.5 is not suitable for immunohistochemical staining of formalin-fixed paraffin embedded sections.Does not cross-react with other haplotypes (e.g., d, f, j, k, p, q, r, s, u, v).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA