product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 785™ anti-mouse CD150 (SLAM)
catalog :
115937
quantity :
50 μg
price :
275 USD
clonality :
monoclonal
host :
rat
conjugate :
Brilliant Violet 785
clone name :
TC15-12F12.2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4a
Kurkewich J, Bikorimana E, Nguyen T, Klopfenstein N, Zhang H, Hallas W, et al. The mirn23a microRNA cluster antagonizes B cell development. J Leukoc Biol. 2016;100:665-677 pubmed
  • flow cytometry; mouse; 1:100; fig 7
Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
  • flow cytometry; mouse; fig 2
Choi Y, Gullicksrud J, Xing S, Zeng Z, Shan Q, Li F, et al. LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nat Immunol. 2015;16:980-90 pubmed publisher
  • flow cytometry; mouse; fig 1
Rao T, Marks Bluth J, Sullivan J, Gupta M, Chandrakanthan V, Fitch S, et al. High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. Stem Cell Res. 2015;14:307-22 pubmed publisher
  • flow cytometry; mouse; fig 1
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed publisher
  • flow cytometry; mouse
CismaÅŸiu V, Popescu L. Telocytes transfer extracellular vesicles loaded with microRNAs to stem cells. J Cell Mol Med. 2015;19:351-8 pubmed publisher
  • flow cytometry; mouse; fig 2
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed publisher
  • flow cytometry; mouse; fig 3
Karamitros D, Patmanidi A, Kotantaki P, Potocnik A, Bähr Ivacevic T, Benes V, et al. Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 2015;142:70-81 pubmed publisher
  • flow cytometry; mouse; fig 2
Sakamoto H, Takeda N, Arai F, Hosokawa K, García P, Suda T, et al. Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Stem Cells. 2015;33:479-90 pubmed publisher
  • flow cytometry; mouse
Xu Y, Swartz K, Siu K, Bhattacharyya M, Minella A. Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism. Oncogene. 2014;33:3161-71 pubmed publisher
Chavez J, Rabe J, Hernandez G, Mills T, Niño K, Davizon Castillo P, et al. PU.1 Expression Defines Distinct Functional Activities in the Phenotypic HSC Compartment of a Murine Inflammatory Stress Model. Cells. 2022;11: pubmed publisher
Young K, Eudy E, Bell R, Loberg M, Stearns T, Sharma D, et al. Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging. Cell Stem Cell. 2021;28:1473-1482.e7 pubmed publisher
Jassinskaja M, Pimková K, Arh N, Johansson E, Davoudi M, Pereira C, et al. Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells. Cell Rep. 2021;34:108894 pubmed publisher
Siamishi I, Iwanami N, Clapes T, Trompouki E, O Meara C, Boehm T. Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Rep. 2020;31:107756 pubmed publisher
Chen X, Deng H, Churchill M, Luchsinger L, Du X, Chu T, et al. Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop. Cell Stem Cell. 2017;21:747-760.e7 pubmed publisher
Morita Y, Ema H, Nakauchi H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exp Med. 2010;207:1173-82 pubmed publisher
Song J, Kiel M, Wang Z, Wang J, Taichman R, Morrison S, et al. An in vivo model to study and manipulate the hematopoietic stem cell niche. Blood. 2010;115:2592-600 pubmed publisher
Cridland S, Keys J, Papathanasiou P, Perkins A. Indian hedgehog supports definitive erythropoiesis. Blood Cells Mol Dis. 2009;43:149-55 pubmed publisher
Jung Y, Song J, Shiozawa Y, Wang J, Wang Z, Williams B, et al. Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche. Stem Cells. 2008;26:2042-51 pubmed publisher
Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, et al. Adult mouse hematopoietic stem cells: purification and single-cell assays. Nat Protoc. 2006;1:2979-87 pubmed
Jung Y, Wang J, Song J, Shiozawa Y, Wang J, Havens A, et al. Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation. Blood. 2007;110:82-90 pubmed
Jordan M, Fletcher J, Pellicci D, Baxter A. Slamf1, the NKT cell control gene Nkt1. J Immunol. 2007;178:1618-27 pubmed
Fraser S, Isern J, Baron M. Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression. Blood. 2007;109:343-52 pubmed
Kim I, He S, Yilmaz O, Kiel M, Morrison S. Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood. 2006;108:737-44 pubmed
product information
Antigen :
CD150
Apps. Abbrev. :
FC
Cat # :
115937
Clone :
TC15-12F12.2
Item :
Brilliant Violet 785™ anti-mouse CD150 (SLAM)
Isotype :
Rat IgG2a, λ
Other Names :
Signaling Lymphocyte Activation Molecule (SLAM), IPO-3
Size :
50 μg
Price (USD) :
275 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV785
Immunogen :
Mouse SLAM-human IgG1 fusion protein
Application Notes :
The TC15-12F12.2 antibody has been reported to enhance the production of IFN-? by Th1 cells stimulated through TCR. Additional reported applications (for the relevant formats) include: immunoprecipitaion^17, enhancing IFN-? production by Th1 cells when stimulated with CD3^1, and inhibiting CD3 induced T cell proliferation^6. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 115949 & 115950).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA