Pacific Blue™ anti-mouse CD150 (SLAM) | BioLegend 115923 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-mouse CD150 (SLAM)

catalog :

115923

quantity :

25 μg

price :

147 USD

clonality :

monoclonal

host :

rat

conjugate :

Pacific Blue

clone name :

TC15-12F12.2

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Kerenyi M, Shao Z, Hsu Y, Guo G, Luc S, O Brien K, et al. Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation. elife. 2013;2:e00633 pubmed publisher
flow cytometry; mouse	Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed publisher
flow cytometry; mouse	Yvan Charvet L, Pagler T, Gautier E, Avagyan S, Siry R, Han S, et al. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science. 2010;328:1689-93 pubmed publisher
	Riether C, Radpour R, Kallen N, Bürgin D, Bachmann C, Schürch C, et al. Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells. Cell Rep. 2021;34:108663 pubmed publisher
	Rodriguez A, Yang C, Furutani E, García de Teresa B, Velázquez M, Filiatrault J, et al. Inhibition of TGFβ1 and TGFβ3 promotes hematopoiesis in Fanconi anemia. Exp Hematol. 2021;93:70-84.e4 pubmed publisher
	Rodriguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, et al. MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia. Cell Stem Cell. 2021;28:33-47.e8 pubmed publisher
	Naka K, Ochiai R, Matsubara E, Kondo C, Yang K, Hoshii T, et al. The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells. Nat Commun. 2020;11:4681 pubmed publisher
	Cabal Hierro L, van Galen P, Prado M, Higby K, Togami K, Mowery C, et al. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020;11:1406 pubmed publisher
	George B, Kao K, Kwon H, Velasco B, Poyser J, Chen A, et al. Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. Cell Stem Cell. 2019;: pubmed publisher
	Mooney C, Cunningham A, Tsapogas P, Toellner K, Brown G. Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment. Int J Mol Sci. 2017;18: pubmed publisher
	Naka K, Jomen Y, Ishihara K, Kim J, Ishimoto T, Bae E, et al. Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells. Nat Commun. 2015;6:8039 pubmed publisher
	Louria Hayon I, Frelin C, Ruston J, Gish G, Jin J, Kofler M, et al. Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling. Proc Natl Acad Sci U S A. 2013;110:20599-604 pubmed publisher
	Morita Y, Ema H, Nakauchi H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exp Med. 2010;207:1173-82 pubmed publisher
	Song J, Kiel M, Wang Z, Wang J, Taichman R, Morrison S, et al. An in vivo model to study and manipulate the hematopoietic stem cell niche. Blood. 2010;115:2592-600 pubmed publisher
	Cridland S, Keys J, Papathanasiou P, Perkins A. Indian hedgehog supports definitive erythropoiesis. Blood Cells Mol Dis. 2009;43:149-55 pubmed publisher
	Jung Y, Song J, Shiozawa Y, Wang J, Wang Z, Williams B, et al. Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche. Stem Cells. 2008;26:2042-51 pubmed publisher
	Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, et al. Adult mouse hematopoietic stem cells: purification and single-cell assays. Nat Protoc. 2006;1:2979-87 pubmed
	Jung Y, Wang J, Song J, Shiozawa Y, Wang J, Havens A, et al. Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation. Blood. 2007;110:82-90 pubmed
	Jordan M, Fletcher J, Pellicci D, Baxter A. Slamf1, the NKT cell control gene Nkt1. J Immunol. 2007;178:1618-27 pubmed
	Fraser S, Isern J, Baron M. Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression. Blood. 2007;109:343-52 pubmed
	Kim I, He S, Yilmaz O, Kiel M, Morrison S. Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood. 2006;108:737-44 pubmed

product information

Antigen :

CD150

Apps. Abbrev. :

Cat # :

115923

Clone :

TC15-12F12.2

Item :

Pacific Blue™ anti-mouse CD150 (SLAM)

Isotype :

Rat IgG2a, λ

Other Names :

Signaling Lymphocyte Activation Molecule (SLAM), IPO-3

Size :

25 μg

Price (USD) :

147 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

Mouse SLAM-human IgG1 fusion protein

Application Notes :

The TC15-12F12.2 antibody has been reported to enhance the production of IFN-? by Th1 cells stimulated through TCR. Additional reported applications (for the relevant formats) include: immunoprecipitaion^17, enhancing IFN-? production by Th1 cells when stimulated with CD3^1, and inhibiting CD3 induced T cell proliferation^6. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 115949 & 115950).;

more info or order :

BioLegend product webpage