PE/Cyanine7 anti-mouse CD126 (IL-6Rα chain) | BioLegend 115813 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-mouse CD126 (IL-6Rα chain)

catalog :

115813

quantity :

25 μg

price :

159 USD

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

D7715A7

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 5b	Yan D, Wang J, Sun H, Zamani A, Zhang H, Chen W, et al. TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. J Exp Med. 2020;217: pubmed publisher
	Harb H, Benamar M, Lai P, Contini P, Griffith J, Crestani E, et al. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021;54:1186-1199.e7 pubmed publisher
	Brandt S, Ballhause T, Bernhardt A, Becker A, Salaru D, Le Deffge H, et al. Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression. J Am Soc Nephrol. 2020;31:2589-2608 pubmed publisher
	Carneiro M, Lopes M, Hohman L, Romano A, David B, Kratofil R, et al. Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir. Cell Host Microbe. 2020;27:752-768.e7 pubmed publisher
	Pham T, Brewer S, Thurston T, Massis L, Honeycutt J, Lugo K, et al. Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection. Cell Host Microbe. 2020;27:54-67.e5 pubmed publisher
	Hoge J, Yan I, Jänner N, Schumacher V, Chalaris A, Steinmetz O, et al. IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling. J Immunol. 2013;190:703-11 pubmed publisher
	Sintes J, Romero X, de Salort J, Terhorst C, Engel P. Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages. J Leukoc Biol. 2010;88:687-97 pubmed publisher
	Yadav M, Rosenbaum J, Goetzl E. Cutting edge: vasoactive intestinal peptide (VIP) induces differentiation of Th17 cells with a distinctive cytokine profile. J Immunol. 2008;180:2772-6 pubmed
	Walker F, Zhang H, Matthews V, Weinstock J, Nice E, Ernst M, et al. IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice. Blood. 2008;111:3978-85 pubmed

product information

Antigen :

CD126

Apps. Abbrev. :

Cat # :

115813

Clone :

D7715A7

Item :

PE/Cyanine7 anti-mouse CD126 (IL-6Rα chain)

Isotype :

Rat IgG2b, κ

Other Names :

IL-6 Receptor α chain, IL-6R

Size :

25 μg

Price (USD) :

159 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PE_CYANINE7

Immunogen :

OKT4 hybridoma cells

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation^1,2,5, in vivo receptor blocking^1-2,4-6,8, and in vitro neutralization^7. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 115806) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 115804) or biotinylated anti-rat IgG second step (Cat. No. 405402), followed by SAv-PE (Cat. No. 405204)). The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 115808).Please note, this clone had previously reported reactivity to rat, however upon further testing it has been determined to not react with rat.;

more info or order :

BioLegend product webpage