APC anti-mouse CD126 (IL-6Rα chain) | BioLegend 115812 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-mouse CD126 (IL-6Rα chain)

catalog :

115812

quantity :

100 μg

price :

296 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

D7715A7

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Reference
Yousif A, Ronsard L, Shah P, Omatsu T, Sangesland M, Bracamonte Moreno T, et al. The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells. Immunity. 2021;54:235-246.e5 pubmed publisher
Figueiredo M, Figueiredo Neto M, Salameh J, Decker R, Letteri R, Chan Seng D, et al. Ligand-Mediated Targeting of Cytokine Interleukin-27 Enhances Its Bioactivity In Vivo. Mol Ther Methods Clin Dev. 2020;17:739-751 pubmed publisher
Lee C, Kwon H, Kang H, Kim Y, Nam J, Won Y, et al. Ets1 suppresses atopic dermatitis by suppressing pathogenic T cell responses. JCI Insight. 2019;4: pubmed publisher
Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, et al. Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation. Cell Rep. 2019;26:1854-1868.e5 pubmed publisher

product information

Antigen :

CD126

Apps. Abbrev. :

Cat # :

115812

Clone :

D7715A7

Item :

APC anti-mouse CD126 (IL-6Rα chain)

Isotype :

Rat IgG2b, κ

Other Names :

IL-6 Receptor α chain, IL-6R

Size :

100 μg

Price (USD) :

296 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

OKT4 hybridoma cells

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation^1,2,5, in vivo receptor blocking^1-2,4-6,8, and in vitro neutralization^7. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 115806) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 115804) or biotinylated anti-rat IgG second step (Cat. No. 405402), followed by SAv-PE (Cat. No. 405204)). The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 115808).Please note, this clone had previously reported reactivity to rat, however upon further testing it has been determined to not react with rat.;

more info or order :

BioLegend product webpage