PE anti-mouse CD126 (IL-6Rα chain) | BioLegend 115806 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse CD126 (IL-6Rα chain)

catalog :

115806

quantity :

200 μg

price :

232 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

D7715A7

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...	Tran N, Ferreira L, Alvarez Moya B, Buttiglione V, Ferrini B, Zordan P, et al. Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier. elife. 2022;11: pubmed publisher
	Chen Z, Amro E, Becker F, Holzer M, Rasa S, Njeru S, et al. Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation. J Exp Med. 2019;216:152-175 pubmed publisher
	Wunderlich C, Ackermann P, Ostermann A, Adams Quack P, Vogt M, Tran M, et al. Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nat Commun. 2018;9:1646 pubmed publisher
	Sintes J, Romero X, de Salort J, Terhorst C, Engel P. Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages. J Leukoc Biol. 2010;88:687-97 pubmed publisher

product information

Antigen :

CD126

Apps. Abbrev. :

Cat # :

115806

Clone :

D7715A7

Item :

PE anti-mouse CD126 (IL-6Rα chain)

Isotype :

Rat IgG2b, κ

Other Names :

IL-6 Receptor α chain, IL-6R

Size :

200 μg

Price (USD) :

232 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

OKT4 hybridoma cells

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation^1,2,5, in vivo receptor blocking^1-2,4-6,8, and in vitro neutralization^7. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 115806) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 115804) or biotinylated anti-rat IgG second step (Cat. No. 405402), followed by SAv-PE (Cat. No. 405204)). The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 115808).Please note, this clone had previously reported reactivity to rat, however upon further testing it has been determined to not react with rat.;

more info or order :

BioLegend product webpage