product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Ultra-LEAF™ Purified anti-mouse CD279 (PD-1)
catalog :
114110
quantity :
1 mg
price :
149 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RMP1-14
reactivity :
mouse
application :
western blot, immunohistochemistry, flow cytometry
more info or order :
citations: 3
Reference
Dheilly E, Battistello E, Katanayeva N, Sungalee S, Michaux J, Duns G, et al. Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma. Cancer Cell. 2020;37:674-689.e12 pubmed publisher
Godoy Calderón M, González Marcano E, Carballo J, Convit A. Evaluation of a ConvitVax/anti-PD-1 combined immunotherapy for breast cancer treatment. Oncotarget. 2019;10:6546-6560 pubmed publisher
Hardcastle J, Mills L, Malo C, Jin F, Kurokawa C, Geekiyanage H, et al. Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment. Neuro Oncol. 2017;19:493-502 pubmed publisher
product information
Antigen :
CD279
Apps. Abbrev. :
FC, IHC, WB, FA
Cat # :
114110
Clone :
RMP1-14
Item :
Ultra-LEAF™ Purified anti-mouse CD279 (PD-1)
Isotype :
Rat IgG2a, κ
Other Names :
Programmed Death-1, CD279, PD 1, PDCD1
Size :
1 mg
Price (USD) :
149 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
ULEAF
Immunogen :
Mouse PD-1 transfected BHK cells
Application Notes :
Additional reported applications (for relevant formats of this clone) include: immunohistochemical staining of acetone-fixed frozen sections^1, Western blotting^2,6, inhibition of macrophages (but not B cells and dendritic cells) costimulated T cell proliferation^3,5, and blocking the binding of PD-1 to B7-H1 or B7-DC^3,4,8. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 114108). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 114110) with a lower endotoxin limit than standard LEAF™ purified antibodies.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA