Purified anti-mouse CD279 (PD-1) | BioLegend 114102 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD279 (PD-1)

catalog :

114102

quantity :

500 μg

price :

127 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RMP1-14

reactivity :

mouse

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 15

Reference
Wei W, Li J, Shen X, Lyu J, Yan C, Tang B, et al. Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation. mSystems. 2022;7:e0046922 pubmed publisher
Arana Y, G xe1 lvez R, Jacobs T. Role of the PD-1/PD-L1 Pathway in Experimental Trypanosoma cruzi Infection and Potential Therapeutic Options. Front Immunol. 2022;13:866120 pubmed publisher
Jang S, Economides K, Moniz R, Sia C, Lewis N, McCoy C, et al. ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance. Commun Biol. 2021;4:497 pubmed publisher
León Letelier R, Castro Medina D, Badillo Godinez O, Tepale Segura A, Huanosta Murillo E, Aguilar Flores C, et al. Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation. Front Immunol. 2020;11:583382 pubmed publisher
Chen L, Zheng H, Yu X, Liu L, Li H, Zhu H, et al. Tumor-Secreted GRP78 Promotes the Establishment of a Pre-metastatic Niche in the Liver Microenvironment. Front Immunol. 2020;11:584458 pubmed publisher
Wang G, Kang X, Chen K, Jehng T, Jones L, Chen J, et al. An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses. Nat Commun. 2020;11:1395 pubmed publisher
Jiao S, Subudhi S, Aparicio A, Ge Z, Guan B, Miura Y, et al. Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy. Cell. 2019;179:1177-1190.e13 pubmed publisher
Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
Zhang H, Chen C, He J, Zhang J, Liu Z, Sun T. Anti-PD-1 Antibody Administration following Hip Fracture Surgery Reverses Immune Dysfunction and Decreases Susceptibility to Infection. Mediators Inflamm. 2019;2019:8492090 pubmed publisher
Chen Y, Li Q, Li X, Ma D, Fang J, Luo L, et al. Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa. Oncoimmunology. 2018;7:e1388484 pubmed publisher
Xu Y, Wang S, Lin Y, Li D, Du M. Tim-3 and PD-1 regulate CD8+ T cell function to maintain early pregnancy in mice. J Reprod Dev. 2017;63:289-294 pubmed publisher
Julian M, Strange H, Ballinger M, Hotchkiss R, Papenfuss T, Crouser E. Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes. PLoS ONE. 2015;10:e0132921 pubmed publisher
LÃ³pez Medina M, Carrillo MartÃn I, Leyva Rangel J, Alpuche Aranda C, Ortiz Navarrete V. Salmonella impairs CD8 T cell response through PD-1: PD-L axis. Immunobiology. 2015;220:1369-80 pubmed publisher
Tsang J, Li D, Ho D, Peng J, Xu A, Lamb J, et al. Novel immunomodulatory effects of adiponectin on dendritic cell functions. Int Immunopharmacol. 2011;11:604-9 pubmed publisher
Meng Q, Yang P, Li B, Zhou H, Huang X, Zhu L, et al. CD4+PD-1+ T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci. 2006;47:4444-52 pubmed

product information

Antigen :

CD279

Apps. Abbrev. :

FC, IHC, WB, FA

Cat # :

114102

Clone :

RMP1-14

Item :

Purified anti-mouse CD279 (PD-1)

Isotype :

Rat IgG2a, κ

Other Names :

Programmed Death-1, CD279, PD 1, PDCD1

Size :

500 μg

Price (USD) :

127 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

Mouse PD-1 transfected BHK cells

Application Notes :

Additional reported applications (for relevant formats of this clone) include: immunohistochemical staining of acetone-fixed frozen sections^1, Western blotting^2,6, inhibition of macrophages (but not B cells and dendritic cells) costimulated T cell proliferation^3,5, and blocking the binding of PD-1 to B7-H1 or B7-DC^3,4,8. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 114108). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 114110) with a lower endotoxin limit than standard LEAF™ purified antibodies.;

more info or order :

BioLegend product webpage