Purified anti-mouse CD279 (PD-1) | BioLegend 114101 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD279 (PD-1)

catalog :

114101

quantity :

50 μg

price :

83 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RMP1-14

reactivity :

mouse

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Reference
León Letelier R, Castro Medina D, Badillo Godinez O, Tepale Segura A, Huanosta Murillo E, Aguilar Flores C, et al. Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation. Front Immunol. 2020;11:583382 pubmed publisher
Wang G, Kang X, Chen K, Jehng T, Jones L, Chen J, et al. An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses. Nat Commun. 2020;11:1395 pubmed publisher
Jiao S, Subudhi S, Aparicio A, Ge Z, Guan B, Miura Y, et al. Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy. Cell. 2019;179:1177-1190.e13 pubmed publisher
Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
Zhang H, Chen C, He J, Zhang J, Liu Z, Sun T. Anti-PD-1 Antibody Administration following Hip Fracture Surgery Reverses Immune Dysfunction and Decreases Susceptibility to Infection. Mediators Inflamm. 2019;2019:8492090 pubmed publisher
Chen Y, Li Q, Li X, Ma D, Fang J, Luo L, et al. Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa. Oncoimmunology. 2018;7:e1388484 pubmed publisher
Xu Y, Wang S, Lin Y, Li D, Du M. Tim-3 and PD-1 regulate CD8+ T cell function to maintain early pregnancy in mice. J Reprod Dev. 2017;63:289-294 pubmed publisher
Julian M, Strange H, Ballinger M, Hotchkiss R, Papenfuss T, Crouser E. Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes. PLoS ONE. 2015;10:e0132921 pubmed publisher
LÃ³pez Medina M, Carrillo MartÃn I, Leyva Rangel J, Alpuche Aranda C, Ortiz Navarrete V. Salmonella impairs CD8 T cell response through PD-1: PD-L axis. Immunobiology. 2015;220:1369-80 pubmed publisher
Tsang J, Li D, Ho D, Peng J, Xu A, Lamb J, et al. Novel immunomodulatory effects of adiponectin on dendritic cell functions. Int Immunopharmacol. 2011;11:604-9 pubmed publisher
Meng Q, Yang P, Li B, Zhou H, Huang X, Zhu L, et al. CD4+PD-1+ T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci. 2006;47:4444-52 pubmed

product information

Antigen :

CD279

Apps. Abbrev. :

FC, IHC, WB, FA

Cat # :

114101

Clone :

RMP1-14

Item :

Purified anti-mouse CD279 (PD-1)

Isotype :

Rat IgG2a, κ

Other Names :

Programmed Death-1, CD279, PD 1, PDCD1

Size :

50 μg

Price (USD) :

83 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

Mouse PD-1 transfected BHK cells

Application Notes :

Additional reported applications (for relevant formats of this clone) include: immunohistochemical staining of acetone-fixed frozen sections^1, Western blotting^2,6, inhibition of macrophages (but not B cells and dendritic cells) costimulated T cell proliferation^3,5, and blocking the binding of PD-1 to B7-H1 or B7-DC^3,4,8. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 114108). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 114110) with a lower endotoxin limit than standard LEAF™ purified antibodies.;

more info or order :

BioLegend product webpage