LEAF™ Purified anti-mouse CD210 (IL-10 R) | BioLegend 112708 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-mouse CD210 (IL-10 R)

catalog :

112708

quantity :

500 μg

price :

280 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

1B1.3a

reactivity :

mouse

application :

neutralization, flow cytometry

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4c	Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, et al. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proc Natl Acad Sci U S A. 2017;114:10443-10448 pubmed publisher
	Bhutiani N, Li Q, Anderson C, Gallagher H, De Jesus M, Singh R, et al. Enhanced gut barrier integrity sensitizes colon cancer to immune therapy. Oncoimmunology. 2018;7:e1498438 pubmed publisher
	Teitz Tennenbaum S, Viglianti S, Roussey J, Levitz S, Olszewski M, Osterholzer J. Autocrine IL-10 Signaling Promotes Dendritic Cell Type-2 Activation and Persistence of Murine Cryptococcal Lung Infection. J Immunol. 2018;201:2004-2015 pubmed publisher
	Tanaka S, Jiang Y, Martinez G, Tanaka K, Yan X, Kurosaki T, et al. Trim33 mediates the proinflammatory function of Th17 cells. J Exp Med. 2018;215:1853-1868 pubmed publisher
	Alhakeem S, McKenna M, Oben K, Noothi S, Rivas J, Hildebrandt G, et al. Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity. J Immunol. 2018;200:4180-4189 pubmed publisher
	Bian Z, Abdelaal A, Shi L, Liang H, Xiong L, Kidder K, et al. Arginase-1 is neither constitutively expressed in nor required for myeloid-derived suppressor cell-mediated inhibition of T-cell proliferation. Eur J Immunol. 2018;48:1046-1058 pubmed publisher
	He L, Zhou S, Qi Q, Chi Y, Zhu J, Xu Z, et al. The regulation of regulation: interleukin-10 increases CD4+ CD25+ regulatory T cells but impairs their immunosuppressive activity in murine models with schistosomiasis japonica or asthma. Immunology. 2018;153:84-96 pubmed publisher
	Clua P, Kanmani P, Zelaya H, Tada A, Kober A, Salva S, et al. Peptidoglycan from Immunobiotic Lactobacillus rhamnosus Improves Resistance of Infant Mice to Respiratory Syncytial Viral Infection and Secondary Pneumococcal Pneumonia. Front Immunol. 2017;8:948 pubmed publisher
	Yue Y, Huang W, Liang J, Guo J, Ji J, Yao Y, et al. IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T Cell Activation via L-Tryptophan and Arginine Depletion and IL-10 Production. PLoS ONE. 2015;10:e0142979 pubmed publisher
	Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, et al. PPAR-?/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis. J Immunol. 2014;192:2357-65 pubmed publisher

product information

Antigen :

CD210

Apps. Abbrev. :

Flow Cytometry, Block

Cat # :

112708

Clone :

1B1.3a

Item :

LEAF™ Purified anti-mouse CD210 (IL-10 R)

Isotype :

Rat IgG1, κ

Other Names :

IL-10R, Interleukin-10 Receptor

Size :

500 μg

Price (USD) :

280 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

LEAF

Immunogen :

Soluble mIL-10R-FLAG-His

Application Notes :

Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of ligand binding 1-5 . For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 112706) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 112704) or biotinylated anti-rat IgG (Cat. No. 405402) second step, followed by SAv-PE (Cat. No. 405204)). The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 112708). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 112710) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).