Purified anti-mouse CD210 (IL-10 R) | BioLegend 112702 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD210 (IL-10 R)

catalog :

112702

quantity :

500 μg

price :

138 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

1B1.3a

reactivity :

mouse

application :

neutralization, flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4c	Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, et al. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proc Natl Acad Sci U S A. 2017;114:10443-10448 pubmed publisher
blocking or activating experiments; mouse; loading ...; fig s2a	Ip W, Hoshi N, Shouval D, Snapper S, Medzhitov R. Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. Science. 2017;356:513-519 pubmed publisher
	Minshawi F, Lanvermann S, McKenzie E, Jeffery R, Couper K, Papoutsopoulou S, et al. The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function. Front Immunol. 2020;11:1794 pubmed publisher
	Khan K, Ponce de León J, Benguigui M, Xu P, Chow A, Cruz Munoz W, et al. Immunostimulatory and anti-tumor metronomic cyclophosphamide regimens assessed in primary orthotopic and metastatic murine breast cancer. NPJ Breast Cancer. 2020;6:29 pubmed publisher
	Bhutiani N, Li Q, Anderson C, Gallagher H, De Jesus M, Singh R, et al. Enhanced gut barrier integrity sensitizes colon cancer to immune therapy. Oncoimmunology. 2018;7:e1498438 pubmed publisher
	Sanctuary M, Huang R, Jones A, Luck M, Aherne C, Jedlicka P, et al. miR-106a deficiency attenuates inflammation in murine IBD models. Mucosal Immunol. 2019;12:200-211 pubmed publisher
	Teitz Tennenbaum S, Viglianti S, Roussey J, Levitz S, Olszewski M, Osterholzer J. Autocrine IL-10 Signaling Promotes Dendritic Cell Type-2 Activation and Persistence of Murine Cryptococcal Lung Infection. J Immunol. 2018;201:2004-2015 pubmed publisher
	Tanaka S, Jiang Y, Martinez G, Tanaka K, Yan X, Kurosaki T, et al. Trim33 mediates the proinflammatory function of Th17 cells. J Exp Med. 2018;215:1853-1868 pubmed publisher
	Alhakeem S, McKenna M, Oben K, Noothi S, Rivas J, Hildebrandt G, et al. Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity. J Immunol. 2018;200:4180-4189 pubmed publisher
	Bian Z, Abdelaal A, Shi L, Liang H, Xiong L, Kidder K, et al. Arginase-1 is neither constitutively expressed in nor required for myeloid-derived suppressor cell-mediated inhibition of T-cell proliferation. Eur J Immunol. 2018;48:1046-1058 pubmed publisher
	He L, Zhou S, Qi Q, Chi Y, Zhu J, Xu Z, et al. The regulation of regulation: interleukin-10 increases CD4+ CD25+ regulatory T cells but impairs their immunosuppressive activity in murine models with schistosomiasis japonica or asthma. Immunology. 2018;153:84-96 pubmed publisher

product information

Antigen :

CD210

Apps. Abbrev. :

FC, Block

Cat # :

112702

Clone :

1B1.3a

Item :

Purified anti-mouse CD210 (IL-10 R)

Isotype :

Rat IgG1, κ

Other Names :

IL-10R, Interleukin-10 Receptor

Size :

500 μg

Price (USD) :

138 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

Soluble mIL-10R-FLAG-His

Application Notes :

Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of ligand binding^1-5. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 112706) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 112704) or biotinylated anti-rat IgG (Cat. No. 405402) second step, followed by SAv-PE (Cat. No. 405204)). The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 112710) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin < 0.01 EU/µg).;

more info or order :

BioLegend product webpage