product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 700 anti-mouse CD45.1
catalog :
110723
quantity :
25 μg
price :
101 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF700
clone name :
A20
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 112
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2a, 3b
Koutn xed k J, Klepsch V, Pommermayr M, Thuille N, Baier G, Siegmund K. A MLR-Based Approach to Analyze Regulators of T Lymphocyte Activation In Vivo. Int J Mol Sci. 2022;23: pubmed publisher
  • flow cytometry; mouse; loading ...; fig e5h
Brown G, Ca xf1 ete P, Wang H, Medhavy A, Bones J, Roco J, et al. TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022;605:349-356 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Liu H, Pedros C, Kong K, Canonigo Balancio A, Xue W, Altman A. Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy. J Immunother Cancer. 2021;9: pubmed publisher
  • flow cytometry; mouse; 1:300; loading ...; fig s3f, s4c
Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed publisher
  • flow cytometry; mouse; loading ...
Winn N, Wolf E, Cottam M, Bhanot M, Hasty A. Myeloid-specific deletion of ferroportin impairs macrophage bioenergetics but is disconnected from systemic insulin action in adult mice. Am J Physiol Endocrinol Metab. 2021;321:E376-E391 pubmed publisher
  • flow cytometry; mouse; fig 4a
Forman R, Logunova L, Smith H, Wemyss K, Mair I, Boon L, et al. Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages. PLoS Pathog. 2021;17:e1009768 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
  • flow cytometry; mouse; 1:200; fig 2g
Zhang S, Li L, Xie D, Reddy S, Sleasman J, Ma L, et al. Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1. Front Immunol. 2021;12:620437 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5f
Yang C, Kwon D, Kim M, Im S, Lee Y. Commensal Microbiome Expands Tγδ17 Cells in the Lung and Promotes Particulate Matter-Induced Acute Neutrophilia. Front Immunol. 2021;12:645741 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Hamminger P, Marchetti L, Preglej T, Platzer R, Zhu C, Kamnev A, et al. Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases. J Autoimmun. 2021;119:102610 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Page N, Lemeille S, Vincenti I, Klimek B, Mariotte A, Wagner I, et al. Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling. Nat Commun. 2021;12:1009 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5a
Yao C, Lou G, Sun H, Zhu Z, Sun Y, Chen Z, et al. BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells. Nat Immunol. 2021;22:370-380 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Xu K, Yin N, Peng M, Stamatiades E, Shyu A, Li P, et al. Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity. Science. 2021;371:405-410 pubmed publisher
  • flow cytometry; mouse; fig 3d
Zhao L, Hu S, Davila M, Yang J, Lin Y, Albanese J, et al. Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation. Mucosal Immunol. 2021;14:420-430 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 4e
Fernandes R, Li C, Wang G, Yang X, Savvides C, Glassman C, et al. Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3b
Svensson M, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody K, et al. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020;6:eaba4353 pubmed publisher
  • flow cytometry; mouse; 1:200
Castiello M, Bosticardo M, Sacchetti N, Calzoni E, Fontana E, Yamazaki Y, et al. Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency. J Allergy Clin Immunol. 2021;147:309-320.e6 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 3a
Stebegg M, Bignon A, Hill D, Silva Cayetano A, Krueger C, Vanderleyden I, et al. Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 8a, 8b
Wuggenig P, Kaya B, Melhem H, Ayata C, Hruz P, Sayan A, et al. Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice. Commun Biol. 2020;3:130 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5g,
Sun D, Zhang M, Sun P, Liu G, Strickland A, Chen Y, et al. VCAM1/VLA4 interaction mediates Ly6Clow monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection. PLoS Pathog. 2020;16:e1008361 pubmed publisher
  • flow cytometry; mouse; 2 ug/ml; loading ...; fig s26a
Wang J, Li P, Yu Y, Fu Y, Jiang H, Lu M, et al. Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science. 2020;367: pubmed publisher
  • flow cytometry; mouse; 1:600; loading ...; fig 1s1a
Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1h
Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, et al. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice. Nat Commun. 2019;10:1492 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s10b
Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019;567:249-252 pubmed publisher
  • flow cytometry; mouse; 1:800; loading ...; fig s12a
Grootjans J, Krupka N, Hosomi S, Matute J, Hanley T, Saveljeva S, et al. Epithelial endoplasmic reticulum stress orchestrates a protective IgA response. Science. 2019;363:993-998 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
He S, Kahles F, Rattik S, Nairz M, McAlpine C, Anzai A, et al. Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease. Nature. 2019;566:115-119 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a, 3b
Maseda D, Banerjee A, Johnson E, Washington M, Kim H, Lau K, et al. mPGES-1-Mediated Production of PGE2 and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation. Front Immunol. 2018;9:2954 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e3d
Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Lund H, Pieber M, Parsa R, Han J, Grommisch D, Ewing E, et al. Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells. Nat Commun. 2018;9:4845 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Klement J, Paschall A, Redd P, Ibrahim M, Lu C, Yang D, et al. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. J Clin Invest. 2018;128:5549-5560 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Mahr B, Pilat N, Granofszky N, Wiletel M, Muckenhuber M, Maschke S, et al. Hybrid resistance to parental bone marrow grafts in nonlethally irradiated mice. Am J Transplant. 2019;19:591-596 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4c
Singh M, Ni M, Sullivan J, Hamerman J, Campbell D. B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation. J Exp Med. 2018;215:2429-2443 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e8a
Wan X, Zinselmeyer B, Zakharov P, Vomund A, Taniguchi R, Santambrogio L, et al. Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. Nature. 2018;560:107-111 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Polonsky M, Rimer J, Kern Perets A, Zaretsky I, Miller S, Bornstein C, et al. Induction of CD4 T cell memory by local cellular collectivity. Science. 2018;360: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Yao Y, Huang W, Li X, Li X, Qian J, Han H, et al. Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice. Front Immunol. 2018;9:965 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Shaw T, Houston S, Wemyss K, Bridgeman H, Barbera T, Zangerle Murray T, et al. Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression. J Exp Med. 2018;215:1507-1518 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Hsiao H, Fernandez R, Tanaka S, Li W, Spahn J, Chiu S, et al. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β. J Clin Invest. 2018;128:2833-2847 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1e
Tanaka S, Pfleger C, Lai J, Roan F, Sun S, Ziegler S. KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners. Cell Rep. 2018;23:796-807 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3c
  • flow cytometry; mouse; 1:200; loading ...; fig s4b
Yeh C, Nojima T, Kuraoka M, Kelsoe G. Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density. Nat Commun. 2018;9:928 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1e
Tinoco R, Carrette F, Henriquez M, Fujita Y, Bradley L. Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells. J Immunol. 2018;200:2690-2702 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Trapecar M, Khan S, Cohn B, Wu F, Sanjabi S. B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunol. 2018;11:1158-1167 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4f
Clarke A, Riffelmacher T, Braas D, Cornall R, Simon A. B1a B cells require autophagy for metabolic homeostasis and self-renewal. J Exp Med. 2018;215:399-413 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2d
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Ibrahim M, Scozzi D, Toth K, Ponti D, Kreisel D, Menna C, et al. Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion. J Immunol. 2018;200:847-856 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2b
Zhang S, Takaku M, Zou L, Gu A, Chou W, Zhang G, et al. Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation. Nature. 2017;551:105-109 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, et al. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017;214:1453-1469 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Inoue T, Shinnakasu R, Ise W, Kawai C, Egawa T, Kurosaki T. The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help. J Exp Med. 2017;214:1181-1198 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1h
Schneider C, Nobs S, Heer A, Hirsch E, Penninger J, Siggs O, et al. Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection. J Leukoc Biol. 2017;101:367-376 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6
Damle S, Martin R, Cross J, Conrad D. Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis. Mucosal Immunol. 2017;10:205-214 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Yabas M, Jing W, Shafik S, Bröer S, Enders A. ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes. PLoS ONE. 2016;11:e0146774 pubmed publisher
  • flow cytometry; mouse
Mise Omata S, Alles N, Fukazawa T, Aoki K, Ohya K, Jimi E, et al. NF-?B RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation. Int Immunol. 2014;26:607-18 pubmed publisher
  • flow cytometry; mouse
Breuer J, Schwab N, Schneider Hohendorf T, Marziniak M, Mohan H, Bhatia U, et al. Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity. Ann Neurol. 2014;75:739-58 pubmed publisher
  • flow cytometry; mouse
Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed publisher
van Elsas M, Labrie C, Etzerodt A, Charoentong P, van Stigt Thans J, van Hall T, et al. Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy. J Immunother Cancer. 2023;11: pubmed publisher
Scherer S, Oberle S, Kanev K, Gerullis A, Wu M, de Almeida G, et al. Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development. Nat Immunol. 2023;24:501-515 pubmed publisher
Horková V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, et al. Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nat Immunol. 2023;24:174-185 pubmed publisher
Paprckova D, Niederlova V, Moudra A, Drobek A, Pribikova M, Janusova S, et al. Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections. Front Immunol. 2022;13:1009198 pubmed publisher
Park J, Kim C, Kim H, Kim H, Lee J, Lee H. Protocol to analyze antitumor immunity of orthotopic injection and spontaneous murine high-grade glioma models using flow cytometry and single-cell RNA sequencing. STAR Protoc. 2022;3:101607 pubmed publisher
Tondini E, Reintjens N, Castello G, Arakelian T, Isendoorn M, Camps M, et al. Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control. NPJ Vaccines. 2022;7:64 pubmed publisher
Kerdidani D, Aerakis E, Verrou K, Angelidis I, Douka K, Maniou M, et al. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. J Exp Med. 2022;219: pubmed publisher
Li J, Xu B, He M, Zong X, Cunningham T, Sha C, et al. Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation. Cell Rep. 2021;37:110124 pubmed publisher
Castellanos C, Ren X, Gonzalez S, Li H, Schroeder A, Liang H, et al. Lymph node-resident dendritic cells drive TH2 cell development involving MARCH1. Sci Immunol. 2021;6:eabh0707 pubmed publisher
Chao J, Korzinkin M, Zhavoronkov A, Ozerov I, Walker M, Higgins K, et al. Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma. Cell Rep Med. 2021;2:100399 pubmed publisher
Li C, Wang G, Sivasami P, Ramirez R, Zhang Y, Benoist C, et al. Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metab. 2021;33:1610-1623.e5 pubmed publisher
Baasch S, Giansanti P, Kolter J, Riedl A, Forde A, Runge S, et al. Cytomegalovirus subverts macrophage identity. Cell. 2021;184:3774-3793.e25 pubmed publisher
Rodriguez L, Duchez P, Touya N, Debeissat C, Guitart A, Pasquet J, et al. α-Tocopherol Attenuates Oxidative Phosphorylation of CD34+ Cells, Enhances Their G0 Phase Fraction and Promotes Hematopoietic Stem and Primitive Progenitor Cell Maintenance. Biomolecules. 2021;11: pubmed publisher
Baldwin S, Reese V, Larsen S, Beebe E, Guderian J, Orr M, et al. Prophylactic efficacy against Mycobacterium tuberculosis using ID93 and lipid-based adjuvant formulations in the mouse model. PLoS ONE. 2021;16:e0247990 pubmed publisher
Chen Z, Arai E, Khan O, Zhang Z, Ngiow S, He Y, et al. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell. 2021;184:1262-1280.e22 pubmed publisher
Zhang J, Wu Q, Johnson C, Pham G, Kinder J, Olsson A, et al. In situ mapping identifies distinct vascular niches for myelopoiesis. Nature. 2021;590:457-462 pubmed publisher
Grigsby S, Friedman A, Chase J, Waas B, Ropa J, Serio J, et al. Elucidating the Importance of DOT1L Recruitment in MLL-AF9 Leukemia and Hematopoiesis. Cancers (Basel). 2021;13: pubmed publisher
Swarnalekha N, Schreiner D, Litzler L, Iftikhar S, Kirchmeier D, Künzli M, et al. T resident helper cells promote humoral responses in the lung. Sci Immunol. 2021;6: pubmed publisher
Rengarajan S, Knoop K, Rengarajan A, Chai J, Grajales Reyes J, Samineni V, et al. A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea. Cell Rep Med. 2020;1: pubmed publisher
Soon M, Lee H, Engel J, Straube J, Thomas B, Pernold C, et al. Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. Nat Immunol. 2020;21:1597-1610 pubmed publisher
Zeis P, Lian M, Fan X, Herman J, Hernandez D, Gentek R, et al. In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. Immunity. 2020;53:775-792.e9 pubmed publisher
Schuran F, Lommetz C, Steudter A, Ghallab A, Wieschendorf B, Schwinge D, et al. Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice. Cell Mol Gastroenterol Hepatol. 2021;11:371-388 pubmed publisher
Ng S, de Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, et al. The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nat Immunol. 2020;21:1205-1218 pubmed publisher
Behr F, Beumer Chuwonpad A, Kragten N, Wesselink T, Stark R, van Gisbergen K. Circulating memory CD8+ T cells are limited in forming CD103+ tissue-resident memory T cells at mucosal sites after reinfection. Eur J Immunol. 2021;51:151-166 pubmed publisher
Senatus L, López Díez R, Egaña Gorroño L, Liu J, Hu J, Daffu G, et al. RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism. JCI Insight. 2020;5: pubmed publisher
Zenke S, Palm M, Braun J, Gavrilov A, Meiser P, Böttcher J, et al. Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity. 2020;52:313-327.e7 pubmed publisher
Charpentier J, Chen D, Lapinski P, Turner J, Grigorova I, Swanson J, et al. Macropinocytosis drives T cell growth by sustaining the activation of mTORC1. Nat Commun. 2020;11:180 pubmed publisher
Hoyer F, Naxerova K, Schloss M, Hulsmans M, Nair A, Dutta P, et al. Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. 2019;51:899-914.e7 pubmed publisher
Chen Z, Ji Z, Ngiow S, Manne S, Cai Z, Huang A, et al. TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. Immunity. 2019;51:840-855.e5 pubmed publisher
Roco J, Mesin L, Binder S, Nefzger C, Gonzalez Figueroa P, Canete P, et al. Class-Switch Recombination Occurs Infrequently in Germinal Centers. Immunity. 2019;51:337-350.e7 pubmed publisher
Eftychi C, Schwarzer R, Vlantis K, Wachsmuth L, Basic M, Wagle P, et al. Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity. 2019;51:367-380.e4 pubmed publisher
Severe N, Karabacak N, Gustafsson K, Baryawno N, Courties G, Kfoury Y, et al. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25:570-583.e7 pubmed publisher
Kobayashi H, Morikawa T, Okinaga A, Hamano F, Hashidate Yoshida T, Watanuki S, et al. Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo. Cell Rep. 2019;28:145-158.e9 pubmed publisher
Delás M, Jackson B, Kovacević T, Vangelisti S, Munera Maravilla E, Wild S, et al. lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation. Cell Rep. 2019;27:719-729.e6 pubmed publisher
Chen J, Li N, Yin Y, Zheng N, Min M, Lin B, et al. Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells. Cell Rep. 2018;25:3393-3404.e6 pubmed publisher
Säwén P, Eldeeb M, Erlandsson E, Kristiansen T, Laterza C, Kokaia Z, et al. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging. elife. 2018;7: pubmed publisher
Nakamura Ishizu A, Matsumura T, Stumpf P, Umemoto T, Takizawa H, Takihara Y, et al. Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation. Cell Rep. 2018;25:1772-1785.e6 pubmed publisher
Turner J, Ke F, GRIGOROVA I. B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting. Cell Rep. 2018;25:1395-1403.e4 pubmed publisher
Li C, DiSpirito J, Zemmour D, Spallanzani R, Kuswanto W, Benoist C, et al. TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Cell. 2018;174:285-299.e12 pubmed publisher
Herndler Brandstetter D, Ishigame H, Shinnakasu R, Plajer V, Stecher C, Zhao J, et al. KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity. 2018;48:716-729.e8 pubmed publisher
Kleppe M, Koche R, Zou L, van Galen P, Hill C, Dong L, et al. Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. Cancer Cell. 2018;33:29-43.e7 pubmed publisher
Bowers E, Slaughter A, Frenette P, Kuick R, Pello O, Lucas D. Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow. Nat Med. 2018;24:95-102 pubmed publisher
Hayatsu N, Miyao T, Tachibana M, Murakami R, Kimura A, Kato T, et al. Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells. Immunity. 2017;47:268-283.e9 pubmed publisher
Sabouri Z, Perotti S, Spierings E, Humburg P, Yabas M, Bergmann H, et al. IgD attenuates the IgM-induced anergy response in transitional and mature B cells. Nat Commun. 2016;7:13381 pubmed publisher
Koyama M, Cheong M, Markey K, Gartlan K, Kuns R, Locke K, et al. Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease. J Exp Med. 2015;212:1303-21 pubmed publisher
Lucca L, Desbois S, Ramadan A, Ben Nun A, Eisenstein M, Carrié N, et al. Bispecificity for myelin and neuronal self-antigens is a common feature of CD4 T cells in C57BL/6 mice. J Immunol. 2014;193:3267-77 pubmed publisher
Huang W, Jeong A, Kannan A, Huang L, August A. IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function. J Immunol. 2014;193:2267-72 pubmed publisher
Huang W, Huang F, Kannan A, Hu J, August A. ITK tunes IL-4-induced development of innate memory CD8+ T cells in a ?? T and invariant NKT cell-independent manner. J Leukoc Biol. 2014;96:55-63 pubmed publisher
Garidou L, Heydari S, Gossa S, McGavern D. Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection. J Virol. 2012;86:7060-71 pubmed publisher
Semmrich M, Plantinga M, Svensson Frej M, Uronen Hansson H, Gustafsson T, Mowat A, et al. Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses. Mucosal Immunol. 2012;5:150-60 pubmed publisher
Yabas M, Godfrey D, Goodnow C, Hoyne G. Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells. PLoS ONE. 2011;6:e26440 pubmed publisher
Li L, Goetz C, Katerndahl C, Sakaguchi N, Farrar M. A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness. J Immunol. 2010;184:1728-36 pubmed publisher
Withers D, Jaensson E, Gaspal F, McConnell F, Eksteen B, Anderson G, et al. The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals. J Immunol. 2009;183:5079-84 pubmed publisher
Takada K, Jameson S. Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels. J Exp Med. 2009;206:2253-69 pubmed publisher
Lee S, Salek Ardakani S, Mittler R, Croft M. Hypercostimulation through 4-1BB distorts homeostasis of immune cells. J Immunol. 2009;182:6753-62 pubmed publisher
Hosoi A, Takeda Y, Furuichi Y, Kurachi M, Kimura K, Maekawa R, et al. Memory Th1 cells augment tumor-specific CTL following transcutaneous peptide immunization. Cancer Res. 2008;68:3941-9 pubmed publisher
Kenna T, Thomas R, Steptoe R. Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses. Blood. 2008;111:2091-100 pubmed
Beamer C, Holian A. Antigen-presenting cell population dynamics during murine silicosis. Am J Respir Cell Mol Biol. 2007;37:729-38 pubmed
Pascal V, Nathan N, Claudio E, Siebenlist U, Anderson S. NF-kappa B p50/p65 affects the frequency of Ly49 gene expression by NK cells. J Immunol. 2007;179:1751-9 pubmed
product information
Antigen :
CD45.1
Apps. Abbrev. :
FC
Cat # :
110723
Clone :
A20
Item :
Alexa Fluor® 700 anti-mouse CD45.1
Isotype :
Mouse (A.SW) IgG2a, κ
Other Names :
T200, Ly-5.1, LCA
Size :
25 μg
Price (USD) :
101 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A700
Immunogen :
SJL mouse thymocytes and splenocytes
Application Notes :
The A20 antibody does not react with leukocytes or mouse cells expressing the CD45.2 alloantigen. Additional reported applications (for relevant formats of this clone) include: immunoprecipitation^3, in vitro blocking of B cell responses^1,2, immunohistochemical staining of frozen sections: OCT embedded^7 and acetone-fixed^4-6 (direct immunofluorescence detection with fluorochrome conjugated A20 was used in (5) and (6)).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA