product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse CD45.1
catalog :
110705
quantity :
50 μg
price :
59 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
A20
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 121
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s1h
Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, et al. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice. Nat Commun. 2019;10:1492 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Hsiao H, Fernandez R, Tanaka S, Li W, Spahn J, Chiu S, et al. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β. J Clin Invest. 2018;128:2833-2847 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2i
  • flow cytometry; mouse; loading ...; fig s5f
Degn S, van der Poel C, Firl D, Ayoglu B, Al Qureshah F, Bajic G, et al. Clonal Evolution of Autoreactive Germinal Centers. Cell. 2017;170:913-926.e19 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Shi Y, Wu W, Chai Q, Li Q, Hou Y, Xia H, et al. LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration. Nat Commun. 2016;7:12369 pubmed publisher
  • flow cytometry; mouse
Friedman R, Lindsay R, Lilly J, Nguyen V, Sorensen C, Jacobelli J, et al. An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function. Proc Natl Acad Sci U S A. 2014;111:9223-8 pubmed publisher
  • flow cytometry; mouse
Lee P, Puppi M, Schluns K, Yu Lee L, Dong C, Lacorazza H. The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage. J Immunol. 2014;192:178-88 pubmed publisher
  • flow cytometry; mouse
Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed publisher
Buckley M, Sun E, George B, Liu L, Schaum N, Xu L, et al. Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain. Nat Aging. 2023;3:121-137 pubmed publisher
Patton T, Zhao Z, Lim X, Eddy E, Wang H, Nelson A, et al. RIPK3 controls MAIT cell accumulation during development but not during infection. Cell Death Dis. 2023;14:111 pubmed publisher
Ernst M, Pronk E, van Dijk C, van Strien P, van Tienhoven T, Wevers M, et al. Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of RUNX1-FPD. Hemasphere. 2023;7:e824 pubmed publisher
Kasuya T, Tanaka S, Tamura J, Etori K, Shoda J, Hattori K, et al. Epithelial cell-derived cytokine TSLP activates regulatory T cells by enhancing fatty acid uptake. Sci Rep. 2023;13:1653 pubmed publisher
Ali L, Garrido Castro A, Lenehan P, Bollenrucher N, Stump C, Dougan M, et al. PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. J Exp Med. 2023;220: pubmed publisher
Oh S, Mao X, Manfredo Vieira S, Lee J, Patel D, Choi E, et al. Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells. Nat Biotechnol. 2023;41:1229-1238 pubmed publisher
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Parga Vidal L, Taggenbrock R, Beumer Chuwonpad A, Aglmous H, Kragten N, Behr F, et al. Hobit and Blimp-1 regulate TRM abundance after LCMV infection by suppressing tissue exit pathways of TRM precursors. Eur J Immunol. 2022;52:1095-1111 pubmed publisher
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Schönberger K, Obier N, Romero Mulero M, Cauchy P, Mess J, Pavlovich P, et al. Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity. Cell Stem Cell. 2022;29:131-148.e10 pubmed publisher
Yang X, Ge L, Wang J. BECN1 modulates hematopoietic stem cells by targeting Caspase-3-GSDME-mediated pyroptosis. Blood Sci. 2020;2:89-99 pubmed publisher
Wu G, Xu Y, Schultz R, Chen H, Xie J, Deng M, et al. LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2-cFLIP-NF-κB signaling axis. Nat Cancer. 2021;2:1170-1184 pubmed publisher
Okubo A, Uchida Y, Higashi Y, Sato T, Ogawa Y, Ryuge A, et al. CD147 Is Essential for the Development of Psoriasis via the Induction of Th17 Cell Differentiation. Int J Mol Sci. 2021;23: pubmed publisher
Duan Q, Ding J, Li F, Liu X, Zhao Y, Yu H, et al. Sirtuin 5 is Dispensable for CD8+ T Cell Effector and Memory Differentiation. Front Cell Dev Biol. 2021;9:761193 pubmed publisher
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Bonnet C, Gou P, Girel S, Bansaye V, Lacout C, Bailly K, et al. Multistage hematopoietic stem cell regulation in the mouse: A combined biological and mathematical approach. iScience. 2021;24:103399 pubmed publisher
Liu Y, Debo B, Li M, Shi Z, Sheng W, Shi Y. LSD1 inhibition sustains T cell invigoration with a durable response to PD-1 blockade. Nat Commun. 2021;12:6831 pubmed publisher
Chen X, MacNabb B, Flood B, Blazar B, Kline J. Divergent fates of antigen-specific CD8+ T cell clones in mice with acute leukemia. Cell Rep. 2021;37:109991 pubmed publisher
Stephens W, Kubinak J, Ghazaryan A, Bauer K, Bell R, Buhrke K, et al. Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep. 2021;37:109916 pubmed publisher
Lawson H, van de Lagemaat L, Barile M, Tavosanis A, Durko J, Villacreces A, et al. CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation. Stem Cell Reports. 2021;16:2784-2797 pubmed publisher
Chang M, Levescot A, Nelson Maney N, Blaustein R, Winden K, Morris A, et al. Arthritis flares mediated by tissue-resident memory T cells in the joint. Cell Rep. 2021;37:109902 pubmed publisher
Sharma G, Frei A, Narayanan J, Gasperetti T, Veley D, Amjad A, et al. Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells. PLoS ONE. 2021;16:e0259042 pubmed publisher
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Guo H, Cooper S, Friedman A. In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis. PLoS ONE. 2016;11:e0150809 pubmed publisher
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product information
Antigen :
CD45.1
Apps. Abbrev. :
FC
Cat # :
110705
Clone :
A20
Item :
FITC anti-mouse CD45.1
Isotype :
Mouse (A.SW) IgG2a, κ
Other Names :
T200, Ly-5.1, LCA
Size :
50 μg
Price (USD) :
59 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Immunogen :
SJL mouse thymocytes and splenocytes
Application Notes :
The A20 antibody does not react with leukocytes or mouse cells expressing the CD45.2 alloantigen. Additional reported applications (for relevant formats of this clone) include: immunoprecipitation^3, in vitro blocking of B cell responses^1,2, immunohistochemical staining of frozen sections: OCT embedded^7 and acetone-fixed^4-6 (direct immunofluorescence detection with fluorochrome conjugated A20 was used in (5) and (6)).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA