APC/Fire™ 750 anti-mouse TCR β chain | BioLegend 109246 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Fire™ 750 anti-mouse TCR β chain

catalog :

109246

quantity :

100 μg

price :

237 USD

clonality :

monoclonal

host :

hamsters

conjugate :

APC

clone name :

H57-597

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1d	Poncette L, Chen X, Lorenz F, Blankenstein T. Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression. J Clin Invest. 2019;129:324-335 pubmed publisher
flow cytometry; mouse; loading ...; fig 5d	Vuckovic S, Minnie S, Smith D, Gartlan K, Watkins T, Markey K, et al. Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019;129:106-121 pubmed publisher
	Mudd P, Minervina A, Pogorelyy M, Turner J, Kim W, Kalaidina E, et al. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans. Cell. 2022;185:603-613.e15 pubmed publisher
	Müller T, Jarosch S, Hammel M, Leube J, Grassmann S, Bernard B, et al. Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy. Cell Rep Med. 2021;2:100374 pubmed publisher
	Jaeger N, McDonough R, Rosen A, Hernandez Leyva A, Wilson N, Lint M, et al. Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation. Cell Rep. 2020;33:108331 pubmed publisher
	Juillerat A, Tkach D, Yang M, Boyne A, Valton J, Poirot L, et al. Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells. Front Bioeng Biotechnol. 2020;8:678 pubmed publisher
	Chappaz S, Flueck L, Farr A, Rolink A, Finke D. Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice. Blood. 2007;110:3862-70 pubmed
	Tsukumo S, Hirose K, Maekawa Y, Kishihara K, Yasutomo K. Lunatic fringe controls T cell differentiation through modulating notch signaling. J Immunol. 2006;177:8365-71 pubmed

product information

Antigen :

TCR beta chain

Apps. Abbrev. :

Flow Cytometry

Cat # :

109246

Clone :

H57-597

Item :

APC/Fire™ 750 anti-mouse TCR β chain

Isotype :

Armenian Hamster IgG

Other Names :

TCR-β chain, TCR-β, β-TCR

Size :

100 μg

Price (USD) :

237 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

APC_F750

Immunogen :

Affinity purified TCR from mouse DO-11.10 cells

Application Notes :

H57-597 is a hamster mAb directed to an epitope of the C region of TCR ß chain 12 . The H57-597 antibody does not cross-react with ?/d TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate a/ß TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation 2 , in vitro stimulation 2,3 , in vivo depletion 4-6 , and immunohistochemical staining of acetone-fixed frozen sections 7,8,9 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 109253-109258).

more info or order :

BioLegend product webpage