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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse TCR β chain
catalog :
109230
quantity :
50 μg
price :
253 USD
clonality :
monoclonal
host :
hamsters
conjugate :
BV421
clone name :
H57-597
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 34
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 1
Michelet X, Garg S, Wolf B, Tuli A, Ricciardi Castagnoli P, Brenner M. MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b. J Immunol. 2015;194:2079-88 pubmed publisher
Goh P, Wiede F, Zeissig M, Britt K, Liang S, Molloy T, et al. PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer. Sci Adv. 2022;8:eabk3338 pubmed publisher
Bajana S, Pankow A, Liu K, Michniowska M, Urban J, Chen W, et al. Correlation between circulating innate lymphoid cell precursors and thymic function. iScience. 2022;25:103732 pubmed publisher
Gómez Diaz C, Jönsson G, Schodl K, Deszcz L, Bestehorn A, Eislmayr K, et al. The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains. iScience. 2021;24:103241 pubmed publisher
Prosser A, Huang W, Liu L, Dart S, Watson M, De Boer B, et al. Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation. Cell Rep. 2021;35:109141 pubmed publisher
Kawakami R, Kitagawa Y, Chen K, Arai M, Ohara D, Nakamura Y, et al. Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells. Immunity. 2021;54:947-961.e8 pubmed publisher
Ito Y, Sasaki T, Li Y, Tanoue T, Sugiura Y, Skelly A, et al. Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation. Cell Rep. 2021;35:109052 pubmed publisher
Boulch M, Cazaux M, Loe Mie Y, Thibaut R, Corre B, Lemaitre F, et al. A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity. Sci Immunol. 2021;6: pubmed publisher
Levine L, Hiam Galvez K, Marquez D, Tenvooren I, Madden M, Contreras D, et al. Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response. Immunity. 2021;54:829-844.e5 pubmed publisher
Yu M, Pal S, Paterson C, Li J, Tyagi A, Adams J, et al. Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells. J Clin Invest. 2021;131: pubmed publisher
Tyagi A, Darby T, Hsu E, Yu M, Pal S, Dar H, et al. The gut microbiota is a transmissible determinant of skeletal maturation. elife. 2021;10: pubmed publisher
Watanabe M, Lu Y, Breen M, Hodes R. B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms. Nat Commun. 2020;11:6264 pubmed publisher
Harsha Krovi S, Zhang J, Michaels Foster M, Brunetti T, Loh L, Scott Browne J, et al. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020;11:6238 pubmed publisher
Fennell L, Gómez Diaz C, Deszcz L, Kavirayani A, Hoffmann D, Yanagitani K, et al. Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. EMBO J. 2020;:e103303 pubmed publisher
Trivedi S, Labuz D, Anderson C, Araújo C, Blair A, Middleton E, et al. Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis. elife. 2020;9: pubmed publisher
Soon M, Lee H, Engel J, Straube J, Thomas B, Pernold C, et al. Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. Nat Immunol. 2020;21:1597-1610 pubmed publisher
Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed publisher
Jandke A, Melandri D, Monin L, Ushakov D, Laing A, Vantourout P, et al. Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments. Nat Commun. 2020;11:3769 pubmed publisher
Xiao S, Bod L, Pochet N, KOTA S, Hu D, Madi A, et al. Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation. Cell Rep. 2020;32:107892 pubmed publisher
Iwanami N, Takeshita K, Lawir D, Suetake I, Tajima S, Sikora K, et al. Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience. 2020;23:101260 pubmed publisher
Jackson Jones L, Smith P, Portman J, Magalhaes M, Mylonas K, Vermeren M, et al. Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants. Immunity. 2020;52:700-715.e6 pubmed publisher
Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher
Muri J, Thut H, Bornkamm G, Kopf M. B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis. Cell Rep. 2019;29:2731-2744.e4 pubmed publisher
Tyagi A, Yu M, Darby T, Vaccaro C, Li J, Owens J, et al. The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression. Immunity. 2018;49:1116-1131.e7 pubmed publisher
Chen S, Luperchio T, Wong X, Doan E, Byrd A, Roy Choudhury K, et al. A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus. Cell Rep. 2018;25:1729-1740.e6 pubmed publisher
Guo X, Dash P, Crawford J, Allen E, Zamora A, Boyd D, et al. Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity. Immunity. 2018;49:531-544.e6 pubmed publisher
Nagatake T, Suzuki H, Hirata S, Matsumoto N, Wada Y, Morimoto S, et al. Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice. Int Immunol. 2018;30:471-481 pubmed publisher
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product information
Antigen :
TCR beta chain
Apps. Abbrev. :
Flow Cytometry, IHC-F
Cat # :
109230
Clone :
H57-597
Item :
Brilliant Violet 421™ anti-mouse TCR β chain
Isotype :
Armenian Hamster IgG
Other Names :
TCR-β chain, TCR-β, β-TCR
Size :
50 μg
Price (USD) :
253 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
BV421
Immunogen :
Affinity purified TCR from mouse DO-11.10 cells
Application Notes :
H57-597 is a hamster mAb directed to an epitope of the C region of TCR ß chain 12 . The H57-597 antibody does not cross-react with ?/d TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate a/ß TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation 2 , in vitro stimulation 2,3 , in vivo depletion 4-6 , and immunohistochemical staining of acetone-fixed frozen sections 7,8,9 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 109253-109258).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA