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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse TCR β chain
catalog :
109207
quantity :
50 μg
price :
66 USD
clonality :
monoclonal
host :
hamsters
conjugate :
PE
clone name :
H57-597
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s5b
Wolf Y, Bartok O, Patkar S, Eli G, Cohen S, Litchfield K, et al. UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell. 2019;179:219-235.e21 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Qian L, Bajana S, Georgescu C, Peng V, Wang H, Adrianto I, et al. Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019;216:884-899 pubmed publisher
Wagner K, Mateyka L, Jarosch S, Grass V, Weber S, Schober K, et al. Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection. Cell Rep. 2022;38:110214 pubmed publisher
Paiva R, Sousa A, Ramos C, Avila M, Lilue J, Paixão T, et al. Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint. Cell Rep. 2021;35:108967 pubmed publisher
Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed publisher
Rustenhoven J, Drieu A, Mamuladze T, de Lima K, Dykstra T, Wall M, et al. Functional characterization of the dural sinuses as a neuroimmune interface. Cell. 2021;184:1000-1016.e27 pubmed publisher
Montel Hagen A, Sun V, Casero D, Tsai S, Zampieri A, Jackson N, et al. In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells. Cell Rep. 2020;33:108320 pubmed publisher
Kobia F, Preusse K, Dai Q, Weaver N, Hass M, Chaturvedi P, et al. Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation. PLoS Biol. 2020;18:e3000850 pubmed publisher
Perry J, Tian S, Sengottuvel N, Harrison E, Gorentla B, Kapadia C, et al. Pulmonary Delivery of Nanoparticle-Bound Toll-like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer. ACS Nano. 2020;14:7200-7215 pubmed publisher
Tanno H, McDaniel J, Stevens C, Voss W, Li J, Durrett R, et al. A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires. Sci Adv. 2020;6:eaay9093 pubmed publisher
Pereira J, Gerber J, Ghidinelli M, Gerber D, Tortola L, Ommer A, et al. Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy. Hum Mol Genet. 2020;29:1253-1273 pubmed publisher
Steinmann S, Schoedsack M, Heinrich F, Breda P, Ochel A, Tiegs G, et al. Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells. Sci Rep. 2020;10:1071 pubmed publisher
Schaffert A, Hanić M, Novokmet M, Zaytseva O, Krištić J, Lux A, et al. Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo. Front Immunol. 2019;10:3024 pubmed publisher
Ohigashi I, Tanaka Y, Kondo K, Fujimori S, Kondo H, Palin A, et al. Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells. Cell Rep. 2019;29:2901-2916.e6 pubmed publisher
Nagashima H, Mahlakõiv T, Shih H, Davis F, Meylan F, Huang Y, et al. Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation. Immunity. 2019;51:682-695.e6 pubmed publisher
Thilakasiri P, Huynh J, Poh A, Tan C, Nero T, Tran K, et al. Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth. EMBO Mol Med. 2019;11: pubmed publisher
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher
Porrello A, Leslie P, Harrison E, Gorentla B, Kattula S, Ghosh S, et al. Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Nat Commun. 2018;9:1988 pubmed publisher
Perry J, Russler Germain E, Zhou Y, Purtha W, Cooper M, Choi J, et al. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018;48:923-936.e4 pubmed publisher
Young A, Ngiow S, Madore J, Reinhardt J, Landsberg J, Chitsazan A, et al. Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis. Cancer Res. 2017;77:4684-4696 pubmed publisher
Poh A, Love C, Masson F, Preaudet A, Tsui C, Whitehead L, et al. Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer Cell. 2017;31:563-575.e5 pubmed publisher
Jaitin D, Weiner A, Yofe I, Lara Astiaso D, Keren Shaul H, David E, et al. Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq. Cell. 2016;167:1883-1896.e15 pubmed publisher
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schluter D, et al. Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice. PLoS ONE. 2016;11:e0162863 pubmed publisher
Beil Wagner J, Dössinger G, Schober K, Vom Berg J, Tresch A, Grandl M, et al. T cell-specific inactivation of mouse CD2 by CRISPR/Cas9. Sci Rep. 2016;6:21377 pubmed publisher
Wolf B, Tatituri R, Almeida C, Le Nours J, Bhowruth V, Johnson D, et al. Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells. J Immunol. 2015;195:2540-51 pubmed publisher
Tung J, Lee W, Pai M, Chen W, Yeh C, Yeh S. Glutamine modulates CD8??(+) TCR??(+) intestinal intraepithelial lymphocyte expression in mice with polymicrobial sepsis. Nutrition. 2013;29:911-7 pubmed publisher
Mahlios J, Zhuang Y. Contribution of IL-13 to early exocrinopathy in Id3-/- mice. Mol Immunol. 2011;49:227-33 pubmed publisher
Corbett K, Losina E, Nti A, Prokopetz J, Katz J. Population-based rates of revision of primary total hip arthroplasty: a systematic review. PLoS ONE. 2010;5:e13520 pubmed publisher
product information
Antigen :
TCR beta chain
Apps. Abbrev. :
Flow Cytometry
Cat # :
109207
Clone :
H57-597
Item :
PE anti-mouse TCR β chain
Isotype :
Armenian Hamster IgG
Other Names :
TCR-β chain, TCR-β, β-TCR
Size :
50 μg
Price (USD) :
66 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PE
Immunogen :
Affinity purified TCR from mouse DO-11.10 cells
Application Notes :
H57-597 is a hamster mAb directed to an epitope of the C region of TCR ß chain 12 . The H57-597 antibody does not cross-react with ?/d TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate a/ß TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation 2 , in vitro stimulation 2,3 , in vivo depletion 4-6 , and immunohistochemical staining of acetone-fixed frozen sections 7,8,9 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 109253-109258).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA