product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD279 (PD-1)
catalog :
109112
quantity :
100 μg
price :
303 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
RMP1-30
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 22
Reference
Jin S, Yoo Y, Shin H, Kim S, Lee S, Lee C, et al. A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion. Nat Nanotechnol. 2023;18:390-402 pubmed publisher
Zhong M, Gao R, Zhao R, Huang Y, Chen C, Li K, et al. BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia. Cell Death Dis. 2022;13:671 pubmed publisher
Tatsuguchi T, Uruno T, Sugiura Y, Sakata D, Izumi Y, Sakurai T, et al. Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells. Int Immunol. 2022;34:277-289 pubmed publisher
Xing Y, Guo W, Wu M, Xie J, Huang D, Hu P, et al. An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo. Cancer Lett. 2022;529:100-111 pubmed publisher
Shen Y, Li Y, Zhu Q, Wang J, Huang Y, Liang J, et al. The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway. CNS Neurosci Ther. 2022;28:46-63 pubmed publisher
Markov S, Caffrey T, O Connell K, Grunkemeyer J, Shin S, Hanson R, et al. IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer. Mol Cancer Ther. 2021;20:2457-2468 pubmed publisher
Chauveau L, Bridgeman A, Tan T, Beveridge R, Frost J, Rijal P, et al. Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity. EMBO Rep. 2021;22:e52447 pubmed publisher
Cousin N, Cap S, Dihr M, Tacconi C, Detmar M, Dieterich L. Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses. Cancer Res. 2021;81:4133-4144 pubmed publisher
Manukian G, Kivolowitz C, deAngelis T, Shastri A, Savage J, Camphausen K, et al. Caloric Restriction Impairs Regulatory T cells Within the Tumor Microenvironment After Radiation and Primes Effector T cells. Int J Radiat Oncol Biol Phys. 2021;110:1341-1349 pubmed publisher
Wang X, Mao J, Zhou T, Chen X, Tu H, Ma J, et al. Hypoxia-induced myeloid derived growth factor promotes hepatocellular carcinoma progression through remodeling tumor microenvironment. Theranostics. 2021;11:209-221 pubmed publisher
Zhang Y, Dong X, Bai L, Shang X, Zeng Y. MUC1-induced immunosuppression in colon cancer can be reversed by blocking the PD1/PDL1 signaling pathway. Oncol Lett. 2020;20:317 pubmed publisher
Laczkó D, Hogan M, Toulmin S, Hicks P, Lederer K, Gaudette B, et al. A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity. 2020;53:724-732.e7 pubmed publisher
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, et al. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. Cell Rep. 2020;31:107628 pubmed publisher
Valencia Hernandez A, Ng W, Ghazanfari N, Ghilas S, de Menezes M, Holz L, et al. A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice. Cell Host Microbe. 2020;27:950-962.e7 pubmed publisher
Lv Z, Zhang P, Li D, Qin M, Nie L, Wang X, et al. CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models. Oncoimmunology. 2020;9:1747688 pubmed publisher
Perruzza L, Strati F, Gargari G, D Erchia A, Fosso B, Pesole G, et al. Enrichment of intestinal Lactobacillus by enhanced secretory IgA coating alters glucose homeostasis in P2rx7-/- mice. Sci Rep. 2019;9:9315 pubmed publisher
Zhao Y, Harrison D, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep. 2018;24:379-390.e6 pubmed publisher
Lewis K, Selby M, Masters G, Valle J, Dito G, Curtis W, et al. Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models. Oncoimmunology. 2017;7:e1377873 pubmed publisher
Carlsson J, Wold A, Sandberg A, Östman S. The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. PLoS ONE. 2015;10:e0143741 pubmed publisher
Sekiya T, Kondo T, Shichita T, Morita R, Ichinose H, Yoshimura A. Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells. J Exp Med. 2015;212:1623-40 pubmed publisher
Kato Y, Zaid A, Davey G, Mueller S, Nutt S, Zotos D, et al. Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall. J Immunol. 2015;195:1006-14 pubmed publisher
Cedeno Laurent F, Barthel S, Opperman M, Lee D, Clark R, Dimitroff C. Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation. J Immunol. 2010;185:4659-72 pubmed publisher
product information
Antigen :
CD279
Apps. Abbrev. :
FC
Cat # :
109112
Clone :
RMP1-30
Item :
APC anti-mouse CD279 (PD-1)
Isotype :
Rat IgG2b, κ
Other Names :
Programmed Death-1, CD279, PDCD1
Size :
100 μg
Price (USD) :
303 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
Mouse PD-1 transfected BHK cells
Application Notes :
The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC^1.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA