APC/Fire™ 750 anti-mouse CD49b (pan-NK cells) | BioLegend 108926 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Fire™ 750 anti-mouse CD49b (pan-NK cells)

catalog :

108926

quantity :

100 μg

price :

247 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

DX5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2b, 4c	Seung H, Wröbel J, Wadle C, B xfc hler T, Chiang D, Rettkowski J, et al. P2Y12-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction. Basic Res Cardiol. 2022;117:16 pubmed publisher
flow cytometry; mouse; 1:40; loading ...; fig 6e	Wolpaw A, Grossmann L, Dessau J, Dong M, Aaron B, Brafford P, et al. Epigenetic state determines inflammatory sensing in neuroblastoma. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
flow cytometry; mouse; loading ...	Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 5e	Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed publisher
flow cytometry; mouse	Bohannon C, Ende Z, Cao W, Mboko W, Ranjan P, Kumar A, et al. Influenza Virus Infects and Depletes Activated Adaptive Immune Responders. Adv Sci (Weinh). 2021;8:e2100693 pubmed publisher
flow cytometry; mouse	Chu A, Kok S, TSUI J, Lin M, Aguirre B, Wadehra M. Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface. J Reprod Immunol. 2021;145:103309 pubmed publisher
flow cytometry; mouse; loading ...; fig s4	Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
flow cytometry; mouse; loading ...	Yoon S, Song S, Shin J, Kang S, Kim H, You H. Protective Effects of Korean Herbal Remedy against Airway Inflammation in an Allergic Asthma by Suppressing Eosinophil Recruitment and Infiltration in Lung. Antioxidants (Basel). 2020;10: pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Mahr B, Pilat N, Granofszky N, Muckenhuber M, Unger L, Weijler A, et al. Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions. Am J Transplant. 2021;21:968-977 pubmed publisher
	Markov S, Caffrey T, O Connell K, Grunkemeyer J, Shin S, Hanson R, et al. IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer. Mol Cancer Ther. 2021;20:2457-2468 pubmed publisher
	Reed J, Preston Hurlburt P, Philbrick W, Betancur G, Korah M, LUCAS C, et al. The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. PLoS ONE. 2020;15:e0236921 pubmed publisher

product information

Antigen :

CD49b

Apps. Abbrev. :

Cat # :

108926

Clone :

DX5

Item :

APC/Fire™ 750 anti-mouse CD49b (pan-NK cells)

Isotype :

Rat IgM, κ

Other Names :

α2 integrin, VLA-2 α chain, DX5, Integrin α2 chain, ITGA2

Size :

100 μg

Price (USD) :

247 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC_F750

Immunogen :

IL-2-propagated NK1.1 + cells from C57BL/6 mice

Application Notes :

The DX5 clone detects cells expressing relatively high levels of CD49b and may not be useful for the detection of cells expressing low levels of CD49b. DX5 does not block NK cell killing or binding to collagen in vitro. Additional reported applications (for the relevant formats) include: complement-mediated cytotoxicity^2 and immunohistochemical staining^5 of formalin-fixed and paraffin-embedded tissue sections as well as immunohistochemical staining of acetone-fixed frozen sections^10. The binding of DX5 antibody to splenic NK cells can be blocked by HMa2 antibody.;

more info or order :

BioLegend product webpage