APC/Cyanine7 anti-mouse CD49b (pan-NK cells) | BioLegend 108919 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-mouse CD49b (pan-NK cells)

catalog :

108919

quantity :

25 μg

price :

90 USD

clonality :

monoclonal

host :

rat

conjugate :

APC/Cy7

clone name :

DX5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; tbl 1	Jackson Jones L, Duncan S, Magalhaes M, Campbell S, Maizels R, McSorley H, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651 pubmed publisher
	Medler T, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth A, et al. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 2018;34:561-578.e6 pubmed publisher
	Jenkins R, Aref A, Lizotte P, Ivanova E, Stinson S, Zhou C, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018;8:196-215 pubmed publisher
	Grayczyk J, Harvey C, Laczkovich I, Alonzo F. A Lipoylated Metabolic Protein Released by Staphylococcus aureus Suppresses Macrophage Activation. Cell Host Microbe. 2017;22:678-687.e9 pubmed publisher
	Smith A, Smith A. A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza. Sci Rep. 2016;6:38703 pubmed publisher
	Gough D, MariÃ© I, Lobry C, Aifantis I, Levy D. STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation. Blood. 2014;124:2252-61 pubmed publisher
	Honjo K, Kubagawa Y, Jones D, DIZON B, Zhu Z, Ohno H, et al. Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (Fc?R). Proc Natl Acad Sci U S A. 2012;109:15882-7 pubmed
	Younos I, Dafferner A, Gulen D, Britton H, Talmadge J. Tumor regulation of myeloid-derived suppressor cell proliferation and trafficking. Int Immunopharmacol. 2012;13:245-56 pubmed publisher
	Seyoum B, Yano M, Pirofski L. The innate immune response to Streptococcus pneumoniae in the lung depends on serotype and host response. Vaccine. 2011;29:8002-11 pubmed publisher
	Kim H, Lee M, Park A, Park E, Kim D, Ahn J, et al. Reduction of natural killer and natural killer T cells is not protective in cisplatin-induced acute renal failure in mice. Nephrology (Carlton). 2011;16:545-51 pubmed publisher
	Busche A, Schmitz S, Fleige H, Robbins S, Walzer T, Stewart C, et al. Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection. J Immunol. 2011;186:2918-25 pubmed publisher
	Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
	Qiu Q, Ravens I, Seth S, Rathinasamy A, Maier M, Davalos Misslitz A, et al. CD155 is involved in negative selection and is required to retain terminally maturing CD8 T cells in thymus. J Immunol. 2010;184:1681-9 pubmed publisher
	Oertelt S, Lian Z, Cheng C, Chuang Y, Padgett K, He X, et al. Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice. J Immunol. 2006;177:1655-60 pubmed

product information

Antigen :

CD49b

Apps. Abbrev. :

Flow Cytometry

Cat # :

108919

Clone :

DX5

Item :

APC/Cyanine7 anti-mouse CD49b (pan-NK cells)

Isotype :

Rat IgM, κ

Other Names :

α2 integrin, VLA-2 α chain, DX5, Integrin α2 chain, ITGA2

Size :

25 μg

Price (USD) :

90 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC_CYANINE7

Immunogen :

IL-2-propagated NK1.1 + cells from C57BL/6 mice

Application Notes :

The DX5 clone detects cells expressing relatively high levels of CD49b and may not be useful for the detection of cells expressing low levels of CD49b. DX5 does not block NK cell killing or binding to collagen in vitro. Additional reported applications (for the relevant formats) include: complement-mediated cytotoxicity 2 and immunohistochemical staining 5 of formalin-fixed and paraffin-embedded tissue sections as well as immunohistochemical staining of acetone-fixed frozen sections 10 . The binding of DX5 antibody to splenic NK cells can be blocked by HMα2 antibody.

more info or order :

BioLegend product webpage