PerCP/Cyanine5.5 anti-mouse CD49b (pan-NK cells) | BioLegend 108915 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP/Cyanine5.5 anti-mouse CD49b (pan-NK cells)

catalog :

108915

quantity :

25 μg

price :

141 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

DX5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 15

Reference
Rahman S, Aqdas M, Martin E, Tomassoni Ardori F, Songkiatisak P, Oh K, et al. Double knockin mice show NF-κB trajectories in immune signaling and aging. Cell Rep. 2022;41:111682 pubmed publisher
Tao X, Zhang R, Du R, Yu T, Yang H, Li J, et al. EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model. J Exp Med. 2022;219: pubmed publisher
Cai B, Liu Y, Chong Y, Zhang H, Matsunaga A, Fang X, et al. IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies. Mol Cancer. 2021;20:165 pubmed publisher
Wang C, Cui A, Bukenya M, Aung A, Pradhan D, Whittaker C, et al. Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade. Cell Rep. 2021;37:110021 pubmed publisher
Mah Som A, Keppel M, Tobin J, Kolicheski A, Saucier N, Sexl V, et al. Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion. Cell Rep. 2021;35:109209 pubmed publisher
Valdes Mora F, Salomon R, Gloss B, Law A, Venhuizen J, Castillo L, et al. Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype. Cell Rep. 2021;35:108945 pubmed publisher
Korangath P, Ivkov R. Magnet-assisted Flow Cytometry of in vivo Tumors to Quantitate Cell-specific Responses to Magnetic Iron Oxide Nanoparticles. Bio Protoc. 2020;10:e3822 pubmed publisher
Gong Y, Ji P, Yang Y, Xie S, Yu T, Xiao Y, et al. Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets. Cell Metab. 2021;33:51-64.e9 pubmed publisher
Li D, Bradley T, Cain D, Pedroza Pacheco I, Aggelakopoulou M, Parks R, et al. RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures. Immunohorizons. 2020;4:713-728 pubmed publisher
Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao Shen H, et al. Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms. J Clin Invest. 2019;130:1596-1611 pubmed publisher
Kooreman N, Kim Y, de Almeida P, Termglinchan V, Diecke S, Shao N, et al. Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. Cell Stem Cell. 2018;22:501-513.e7 pubmed publisher
Miteva K, Pappritz K, Sosnowski M, El Shafeey M, MÃ¼ller I, Dong F, et al. Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy. Sci Rep. 2018;8:2820 pubmed publisher
Periasamy S, Porter K, Atianand M, T Le H, Earley S, Duffy E, et al. Pyrin-only protein 2 limits inflammation but improves protection against bacteria. Nat Commun. 2017;8:15564 pubmed publisher
Lee L, Ji M, Sinha M, Dong M, Ren X, Wang Y, et al. Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9. PLoS ONE. 2016;11:e0167693 pubmed publisher
Kolawole A, Gonzalez Hernandez M, Turula H, Yu C, Elftman M, Wobus C. Oral Norovirus Infection Is Blocked in Mice Lacking Peyer's Patches and Mature M Cells. J Virol. 2016;90:1499-506 pubmed publisher

product information

Antigen :

CD49b

Apps. Abbrev. :

Cat # :

108915

Clone :

DX5

Item :

PerCP/Cyanine5.5 anti-mouse CD49b (pan-NK cells)

Isotype :

Rat IgM, κ

Other Names :

α2 integrin, VLA-2 α chain, DX5, Integrin α2 chain, ITGA2

Size :

25 μg

Price (USD) :

141 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PERCP_CYANINE5.5

Immunogen :

IL-2-propagated NK1.1 + cells from C57BL/6 mice

Application Notes :

The DX5 clone detects cells expressing relatively high levels of CD49b and may not be useful for the detection of cells expressing low levels of CD49b. DX5 does not block NK cell killing or binding to collagen in vitro. Additional reported applications (for the relevant formats) include: complement-mediated cytotoxicity^2 and immunohistochemical staining^5 of formalin-fixed and paraffin-embedded tissue sections as well as immunohistochemical staining of acetone-fixed frozen sections^10. The binding of DX5 antibody to splenic NK cells can be blocked by HMa2 antibody.;

more info or order :

BioLegend product webpage