Purified anti-mouse CD252 (OX40 Ligand) | BioLegend 108802 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD252 (OX40 Ligand)

catalog :

108802

quantity :

500 μg

price :

136 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RM134L

reactivity :

mouse

application :

neutralization, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s15d	Sugiura D, Maruhashi T, Okazaki I, Shimizu K, Maeda T, Takemoto T, et al. Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses. Science. 2019;364:558-566 pubmed publisher
blocking or activating experiments; mouse; 10 ug/ml; loading ...; fig 5b	Choi I, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, et al. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proc Natl Acad Sci U S A. 2018;115:E686-E695 pubmed publisher
	Pariser D, Hilt Z, Ture S, Blick Nitko S, Looney M, Cleary S, et al. Lung megakaryocytes are immune modulatory cells. J Clin Invest. 2021;131: pubmed publisher
	Hegde S, Krisnawan V, Herzog B, Zuo C, Breden M, Knolhoff B, et al. Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 2020;37:289-307.e9 pubmed publisher
	Garg G, Nikolouli E, Hardtke Wolenski M, Toker A, Ohkura N, Beckstette M, et al. Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells. Oncotarget. 2017;8:35542-35557 pubmed publisher
	Jiang J, Liu C, Liu M, Shen Y, Hu X, Wang Q, et al. OX40 signaling is involved in the autoactivation of CD4+CD28- T cells and contributes to the pathogenesis of autoimmune arthritis. Arthritis Res Ther. 2017;19:67 pubmed publisher
	Zheng X, Ma P, de Paiva C, Cunningham M, Hwang C, Pflugfelder S, et al. TSLP and downstream molecules in experimental mouse allergic conjunctivitis. Invest Ophthalmol Vis Sci. 2010;51:3076-82 pubmed publisher

product information

Antigen :

CD252

Apps. Abbrev. :

Flow Cytometry, IHC-F, Block

Cat # :

108802

Clone :

RM134L

Item :

Purified anti-mouse CD252 (OX40 Ligand)

Isotype :

Rat IgG2b, κ

Other Names :

OX-40L, CD134L, CD252, TNFSF4

Size :

500 μg

Price (USD) :

136 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

Rat NRK-52E cell line transfected with mouse OX-40L

Application Notes :

The RM134L antibody can block the costimulatory activity of OX40L. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections 3 , and in vivo and in vitro blocking of OX-40L-OX-40 functional interaction 1,2,4 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 108808).

more info or order :

BioLegend product webpage