product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse NK-1.1
catalog :
108741
quantity :
50 μg
price :
237 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
PK136
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:300; loading ...
Bielecki P, Riesenfeld S, Hütter J, Torlai Triglia E, Kowalczyk M, Ricardo Gonzalez R, et al. Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature. 2021;592:128-132 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Schanoski A, Le T, Kaiserman D, Rowe C, Prow N, Barboza D, et al. Granzyme A in Chikungunya and Other Arboviral Infections. Front Immunol. 2019;10:3083 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
Duan H, Jing L, Jiang X, Ma Y, Wang D, Xiang J, et al. CD146 bound to LCK promotes T cell receptor signaling and antitumor immune responses in mice. J Clin Invest. 2021;131: pubmed publisher
Hakim R, Zachariadis V, Sankavaram S, Han J, Harris R, Brundin L, et al. Spinal Cord Injury Induces Permanent Reprogramming of Microglia into a Disease-Associated State Which Contributes to Functional Recovery. J Neurosci. 2021;41:8441-8459 pubmed publisher
Garcia L, Tenev T, Newman R, Haich R, Liccardi G, John S, et al. Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance. Nat Commun. 2021;12:3364 pubmed publisher
Boulch M, Cazaux M, Loe Mie Y, Thibaut R, Corre B, Lemaitre F, et al. A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity. Sci Immunol. 2021;6: pubmed publisher
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, et al. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. Cell. 2020;183:1867-1883.e26 pubmed publisher
Bayık D, Zhou Y, Park C, Hong C, Vail D, Silver D, et al. Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner. Cancer Discov. 2020;10:1210-1225 pubmed publisher
Raşid O, Chevalier C, Camarasa T, Fitting C, Cavaillon J, Hamon M. H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammation. Cell Rep. 2019;29:3933-3945.e3 pubmed publisher
Bhattacherjee A, Rodrigues E, Jung J, Luzentales Simpson M, Enterina J, Galleguillos D, et al. Repression of phagocytosis by human CD33 is not conserved with mouse CD33. Commun Biol. 2019;2:450 pubmed publisher
Adams R, Smith C. Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny. Mediators Inflamm. 2019;2019:9160941 pubmed publisher
Renner K, Bruss C, Schnell A, Koehl G, Becker H, Fante M, et al. Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. Cell Rep. 2019;29:135-150.e9 pubmed publisher
Garber C, Soung A, Vollmer L, Kanmogne M, Last A, Brown J, et al. T cells promote microglia-mediated synaptic elimination and cognitive dysfunction during recovery from neuropathogenic flaviviruses. Nat Neurosci. 2019;: pubmed publisher
Santecchia I, Vernel Pauillac F, Raşid O, Quintin J, Gomes Solecki M, Boneca I, et al. Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection. PLoS Pathog. 2019;15:e1007811 pubmed publisher
Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, et al. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019;50:1232-1248.e14 pubmed publisher
LaFleur M, Nguyen T, Coxe M, Yates K, Trombley J, Weiss S, et al. A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system. Nat Commun. 2019;10:1668 pubmed publisher
Dyer D, Medina Ruiz L, Bartolini R, Schuette F, Hughes C, Pallas K, et al. Chemokine Receptor Redundancy and Specificity Are Context Dependent. Immunity. 2019;50:378-389.e5 pubmed publisher
Minutti C, Modak R, MacDonald F, Li F, Smyth D, Dorward D, et al. A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation. Immunity. 2019;50:645-654.e6 pubmed publisher
Wang B, Lim J, Kajikawa T, Li X, Vallance B, Moutsopoulos N, et al. Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis. Cell Rep. 2019;26:1614-1626.e5 pubmed publisher
Collins P, Cella M, Porter S, Li S, Gurewitz G, Hong H, et al. Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells. Cell. 2019;176:348-360.e12 pubmed publisher
Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
Liu H, Archer N, Dillen C, Wang Y, Ashbaugh A, Ortines R, et al. Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses. Cell Host Microbe. 2017;22:653-666.e5 pubmed publisher
Mildner A, Schönheit J, Giladi A, David E, Lara Astiaso D, Lorenzo Vivas E, et al. Genomic Characterization of Murine Monocytes Reveals C/EBP? Transcription Factor Dependence of Ly6C- Cells. Immunity. 2017;46:849-862.e7 pubmed publisher
Lin J, Sodenkamp J, Cunningham D, Deroost K, Tshitenge T, McLaughlin S, et al. Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria. Sci Rep. 2017;7:41722 pubmed publisher
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher
Gordon E, Hart G, Tran T, Waisberg M, Akkaya M, Kim A, et al. Targeting glutamine metabolism rescues mice from late-stage cerebral malaria. Proc Natl Acad Sci U S A. 2015;112:13075-80 pubmed publisher
Lee H, Schlereth S, Park E, Emami Naeini P, Chauhan S, Dana R. A novel pro-angiogenic function for interferon-?-secreting natural killer cells. Invest Ophthalmol Vis Sci. 2014;55:2885-92 pubmed publisher
Bankoti J, Burnett A, Navarro S, Miller A, Rase B, Shepherd D. Effects of TCDD on the fate of naive dendritic cells. Toxicol Sci. 2010;115:422-34 pubmed publisher
Kim J, Huh K, Lee K, Yang J, Kim T. Nickel induces secretion of IFN-gamma by splenic natural killer cells. Exp Mol Med. 2009;41:288-95 pubmed publisher
Kroemer A, Xiao X, Degauque N, Edtinger K, Wei H, Demirci G, et al. The innate NK cells, allograft rejection, and a key role for IL-15. J Immunol. 2008;180:7818-26 pubmed
product information
Antigen :
NK-1.1
Apps. Abbrev. :
Flow Cytometry
Cat # :
108741
Clone :
PK136
Item :
Brilliant Violet 421™ anti-mouse NK-1.1
Isotype :
Mouse IgG2a, κ
Other Names :
NKR-P1C, NKR-P1B, Ly-55, CD161, CD161b, CD161c
Size :
50 μg
Price (USD) :
237 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
NK-1 + cells from mouse spleen and bone marrow
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 1,2 , complement-dependent cytotoxicity 3 , in vivo depletion 4,5,9,10 , mediation of in vitro redirected lysis 6 , blocking of NK cell function 7 , induction of proliferation 8 , immunohistochemical staining of frozen sections 11 , immunofluorescence microscopy 11 , and spatial biology (IBEX) 16,17 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 108712).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA