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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse NK-1.1
catalog :
108707
quantity :
50 μg
price :
50 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
PK136
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 66
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 2 ug/ml; loading ...; fig s3a
Wang J, Li P, Yu Y, Fu Y, Jiang H, Lu M, et al. Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science. 2020;367: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s19c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Martins J, Andoniou C, Fleming P, Kuns R, Schuster I, Voigt V, et al. Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation. Science. 2019;363:288-293 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Cornelissen L, Blanas A, van der Horst J, Kruijssen L, Zaal A, O Toole T, et al. Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis. Int J Cancer. 2019;144:2290-2302 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, et al. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. Cell. 2018;173:634-648.e12 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2e
Mathew N, Baumgartner F, Braun L, O Sullivan D, Thomas S, Waterhouse M, et al. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med. 2018;24:282-291 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Kogo H, Shimizu M, Negishi Y, Uchida E, Takahashi H. Suppression of murine tumour growth through CD8+ cytotoxic T lymphocytes via activated DEC-205+ dendritic cells by sequential administration of ?-galactosylceramide in vivo. Immunology. 2017;151:324-339 pubmed publisher
Zhang R, Earnest J, Kim A, Winkler E, Desai P, Adams L, et al. Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila. Cell Rep. 2019;28:2647-2658.e5 pubmed publisher
Niemann J, Woller N, Brooks J, Fleischmann Mundt B, Martin N, Kloos A, et al. Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy. Nat Commun. 2019;10:3236 pubmed publisher
Nowlan B, Williams E, Doran M, Levesque J. CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains. Haematologica. 2019;: pubmed publisher
LaFleur M, Nguyen T, Coxe M, Yates K, Trombley J, Weiss S, et al. A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system. Nat Commun. 2019;10:1668 pubmed publisher
Isvoranu G, Surcel M, Huică R, Munteanu A, Pirvu I, Ciotaru D, et al. Natural killer cell monitoring in cutaneous melanoma - new dynamic biomarker. Oncol Lett. 2019;17:4197-4206 pubmed publisher
Li J, Wada S, Weaver L, Biswas C, Behrens E, Arany Z. Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis. JCI Insight. 2019;5: pubmed publisher
Salazar V, Jagger B, Mongkolsapaya J, Burgomaster K, Dejnirattisai W, Winkler E, et al. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Rep. 2019;26:1585-1597.e4 pubmed publisher
Hendrikx S, Coso S, Prat Luri B, Wetterwald L, Sabine A, Franco C, et al. Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2. Cell Rep. 2019;26:1227-1241.e6 pubmed publisher
Orr M, Khandhar A, Seydoux E, Liang H, Gage E, Mikasa T, et al. Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology. NPJ Vaccines. 2019;4:1 pubmed publisher
Bachu M, Tamura T, Chen C, Narain A, Nehru V, Sarai N, et al. A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics. J Biol Chem. 2019;294:1904-1914 pubmed publisher
Ovadya Y, Landsberger T, Leins H, Vadai E, Gal H, Biran A, et al. Impaired immune surveillance accelerates accumulation of senescent cells and aging. Nat Commun. 2018;9:5435 pubmed publisher
Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, et al. Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression. Cell Metab. 2018;28:243-255.e5 pubmed publisher
Sartorius R, D Apice L, Barba P, Cipria D, Grauso L, Cutignano A, et al. Vectorized Delivery of Alpha-GalactosylCeramide and Tumor Antigen on Filamentous Bacteriophage fd Induces Protective Immunity by Enhancing Tumor-Specific T Cell Response. Front Immunol. 2018;9:1496 pubmed publisher
Vasamsetti S, Florentin J, Coppin E, Stiekema L, Zheng K, Nisar M, et al. Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation. Immunity. 2018;49:93-106.e7 pubmed publisher
Barry K, Hsu J, Broz M, Cueto F, Binnewies M, Combes A, et al. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018;24:1178-1191 pubmed publisher
Iwamoto H, Abe M, Yang Y, Cui D, Seki T, Nakamura M, et al. Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance. Cell Metab. 2018;28:104-117.e5 pubmed publisher
Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, et al. Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia. PLoS Pathog. 2018;14:e1006955 pubmed publisher
Hiramoto T, Li L, Funk S, Hirata R, Russell D. Nuclease-free Adeno-Associated Virus-Mediated Il2rg Gene Editing in X-SCID Mice. Mol Ther. 2018;26:1255-1265 pubmed publisher
Wu C, He S, Liu J, Wang B, Lin J, Duan Y, et al. Type 1 innate lymphoid cell aggravation of atherosclerosis is mediated through TLR4. Scand J Immunol. 2018;87:e12661 pubmed publisher
Nakamura K, Kassem S, Cleynen A, Chrétien M, Guillerey C, Putz E, et al. Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment. Cancer Cell. 2018;33:634-648.e5 pubmed publisher
Li Z, Gothard E, Coles M, Ambler C. Quantitative Methods for Measuring Repair Rates and Innate-Immune Cell Responses in Wounded Mouse Skin. Front Immunol. 2018;9:347 pubmed publisher
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed publisher
Kim D, Park H, Lim S, Koo J, Lee H, Choi J, et al. Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis. Nat Commun. 2018;9:503 pubmed publisher
Reismann D, Stefanowski J, Gunther R, Rakhymzhan A, Matthys R, Nützi R, et al. Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature. Nat Commun. 2017;8:2153 pubmed publisher
Nakagawa S, Matsumoto M, Katayama Y, Oguma R, Wakabayashi S, Nygaard T, et al. Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation. Cell Host Microbe. 2017;22:667-677.e5 pubmed publisher
Sade Feldman M, Jiao Y, Chen J, Rooney M, Barzily Rokni M, Eliane J, et al. Resistance to checkpoint blockade therapy through inactivation of antigen presentation. Nat Commun. 2017;8:1136 pubmed publisher
Glasner A, Isaacson B, Viukov S, Neuman T, Friedman N, Mandelboim M, et al. Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression. Sci Rep. 2017;7:13090 pubmed publisher
Periasamy S, Porter K, Atianand M, T Le H, Earley S, Duffy E, et al. Pyrin-only protein 2 limits inflammation but improves protection against bacteria. Nat Commun. 2017;8:15564 pubmed publisher
Hulsmans M, Clauss S, Xiao L, Aguirre A, King K, Hanley A, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169:510-522.e20 pubmed publisher
Yang C, Ding P, Wang Q, Zhang L, Zhang X, Zhao J, et al. Inhibition of Complement Retards Ankylosing Spondylitis Progression. Sci Rep. 2016;6:34643 pubmed publisher
Qiu Z, Cervantes J, Cicek B, Mukherjee S, Venkatesh M, Maher L, et al. Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4. Sci Rep. 2016;6:31936 pubmed publisher
Wang Y, Jiang X, Zhu J, Dan Yue -, Zhang X, Wang X, et al. IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice. Sci Rep. 2016;6:31881 pubmed publisher
Zheng M, Qu D, Wang H, Sun Z, Liu X, Chen J, et al. Intranasal Administration of Chitosan Against Influenza A (H7N9) Virus Infection in a Mouse Model. Sci Rep. 2016;6:28729 pubmed publisher
Baglaenko Y, Manion K, Chang N, Gracey E, Loh C, Wither J. IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice. PLoS ONE. 2016;11:e0150515 pubmed publisher
Marsh S, Abud E, Lakatos A, Karimzadeh A, Yeung S, Davtyan H, et al. The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function. Proc Natl Acad Sci U S A. 2016;113:E1316-25 pubmed publisher
Poczobutt J, Nguyen T, Hanson D, Li H, Sippel T, Weiser Evans M, et al. Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment. J Immunol. 2016;196:891-901 pubmed publisher
Han J, Chen X, Chu J, Xu B, Meisen W, Chen L, et al. TGFβ Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response. Cancer Res. 2015;75:5273-82 pubmed publisher
Engel O, Akyüz L, da Costa Goncalves A, Winek K, Dames C, Thielke M, et al. Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke. Stroke. 2015;46:3232-40 pubmed publisher
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Lokken K, Mooney J, Butler B, Xavier M, Chau J, Schaltenberg N, et al. Malaria parasite infection compromises control of concurrent systemic non-typhoidal Salmonella infection via IL-10-mediated alteration of myeloid cell function. PLoS Pathog. 2014;10:e1004049 pubmed publisher
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Huang J, Tsai Y, Chang Y, Wu J, Hung J, Lin K, et al. α-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3. J Immunol. 2014;192:1972-81 pubmed publisher
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Bankoti J, Burnett A, Navarro S, Miller A, Rase B, Shepherd D. Effects of TCDD on the fate of naive dendritic cells. Toxicol Sci. 2010;115:422-34 pubmed publisher
Astrakhan A, Ochs H, Rawlings D. Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells. J Immunol. 2009;182:7370-80 pubmed publisher
Kim J, Huh K, Lee K, Yang J, Kim T. Nickel induces secretion of IFN-gamma by splenic natural killer cells. Exp Mol Med. 2009;41:288-95 pubmed publisher
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Kroemer A, Xiao X, Degauque N, Edtinger K, Wei H, Demirci G, et al. The innate NK cells, allograft rejection, and a key role for IL-15. J Immunol. 2008;180:7818-26 pubmed
Hsieh M, Lai S, Chen J, Sung J, Lin Y, Wu Hsieh B, et al. Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. J Immunol. 2006;177:1855-63 pubmed
product information
Antigen :
NK-1.1
Apps. Abbrev. :
Flow Cytometry
Cat # :
108707
Clone :
PK136
Item :
PE anti-mouse NK-1.1
Isotype :
Mouse IgG2a, κ
Other Names :
NKR-P1C, NKR-P1B, Ly-55, CD161, CD161b, CD161c
Size :
50 μg
Price (USD) :
50 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
NK-1 + cells from mouse spleen and bone marrow
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 1,2 , complement-dependent cytotoxicity 3 , in vivo depletion 4,5,9,10 , mediation of in vitro redirected lysis 6 , blocking of NK cell function 7 , induction of proliferation 8 , immunohistochemical staining of frozen sections 11 , and immunofluorescence microscopy 11 . The LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 108712).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA