product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse Ly-51
catalog :
108308
quantity :
200 μg
price :
292 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
6C3
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1a
Montero Herradón S, García Ceca J, Zapata A. Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation. Front Immunol. 2018;9:1020 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Herzig Y, Nevo S, Bornstein C, Brezis M, Ben Hur S, Shkedy A, et al. Transcriptional programs that control expression of the autoimmune regulator gene Aire. Nat Immunol. 2017;18:161-172 pubmed publisher
  • flow cytometry; mouse; fig 3
Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol. 2015;16:737-45 pubmed publisher
  • flow cytometry; mouse; fig 3.26.3
Jain R, Gray D. Isolation of thymic epithelial cells and analysis by flow cytometry. Curr Protoc Immunol. 2014;107:3.26.1-15 pubmed publisher
  • flow cytometry; mouse
Cowan J, McCarthy N, Parnell S, White A, Bacon A, Serge A, et al. Differential requirement for CCR4 and CCR7 during the development of innate and adaptive ??T cells in the adult thymus. J Immunol. 2014;193:1204-12 pubmed publisher
Paiva R, Sousa A, Ramos C, Avila M, Lilue J, Paixão T, et al. Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint. Cell Rep. 2021;35:108967 pubmed publisher
Chen J, Sivan U, Tan S, Lippo L, De Angelis J, Labella R, et al. High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging. Sci Adv. 2021;7: pubmed publisher
Guyon C, Jmari N, Padonou F, Li Y, Ucar O, Fujikado N, et al. Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus. elife. 2020;9: pubmed publisher
Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher
Jing Y, Kang D, Liu L, Huang H, Chen A, Yang L, et al. Dedicator of cytokinesis protein 2 couples with lymphoid enhancer-binding factor 1 to regulate expression of CD21 and B-cell differentiation. J Allergy Clin Immunol. 2019;: pubmed publisher
Yin S, Gambe R, Sun J, Martinez A, Cartun Z, Regis F, et al. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer Cell. 2019;35:283-296.e5 pubmed publisher
Yoshida H, Lareau C, Ramirez R, Rose S, Maier B, Wroblewska A, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019;176:897-912.e20 pubmed publisher
Ghezraoui H, Oliveira C, Becker J, Bilham K, Moralli D, Anzilotti C, et al. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ. Nature. 2018;560:122-127 pubmed publisher
Li C, Irrazabal T, So C, Berru M, Du L, Lam E, et al. The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining. Nat Commun. 2018;9:1006 pubmed publisher
Koh A, Miller E, Buenrostro J, Moskowitz D, Wang J, Greenleaf W, et al. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol. 2018;19:162-172 pubmed publisher
Bansal K, Yoshida H, Benoist C, Mathis D. The transcriptional regulator Aire binds to and activates super-enhancers. Nat Immunol. 2017;18:263-273 pubmed publisher
Dumont Lagacé M, Brochu S, St Pierre C, Perreault C. Adult thymic epithelium contains nonsenescent label-retaining cells. J Immunol. 2014;192:2219-26 pubmed publisher
Giraud M, Jmari N, Du L, Carallis F, Nieland T, Perez Campo F, et al. An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription. Proc Natl Acad Sci U S A. 2014;111:1491-6 pubmed publisher
product information
Antigen :
Ly-51
Apps. Abbrev. :
Flow Cytometry
Cat # :
108308
Clone :
6C3
Item :
PE anti-mouse Ly-51
Isotype :
Rat IgG2a, κ
Other Names :
6C3/BP-1
Size :
200 μg
Price (USD) :
292 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
C57BL/6 mouse Pre-B lymphoma cell line (L1-2) plus Abelson murine leukemia virus-specific cytotoxic T-cell clones
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 1,2 and immunohistochemical staining 3-5, 7-8 of acetone-fixed frozen sections.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA