Brilliant Violet 510™ anti-mouse Ly-6A/E (Sca-1) | BioLegend 108129 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 510™ anti-mouse Ly-6A/E (Sca-1)

catalog :

108129

quantity :

125 μL

price :

193 USD

clonality :

monoclonal

host :

rat

conjugate :

BV510

clone name :

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s7a, s7b, s7c	Kaur S, Sehgal A, Wu A, Millard S, Batoon L, Sandrock C, et al. Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. J Hematol Oncol. 2021;14:3 pubmed publisher
	Young K, Eudy E, Bell R, Loberg M, Stearns T, Sharma D, et al. Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging. Cell Stem Cell. 2021;28:1473-1482.e7 pubmed publisher
	Ritter M, Klimiankou M, Klimenkova O, Schambach A, Hoffmann D, Schmidt A, et al. Cooperating, congenital neutropenia-associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs. Ann Hematol. 2020;99:2329-2338 pubmed publisher
	van Gastel N, Spinelli J, Sharda A, Schajnovitz A, Baryawno N, Rhee C, et al. Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance. Cell Metab. 2020;32:391-403.e6 pubmed publisher
	Tyrkalska S, Pérez Oliva A, Rodríguez Ruiz L, Martínez Morcillo F, Alcaraz Pérez F, Martínez Navarro F, et al. Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. Immunity. 2019;: pubmed publisher
	Nowlan B, Williams E, Doran M, Levesque J. CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains. Haematologica. 2019;: pubmed publisher
	Loberg M, Bell R, Goodwin L, Eudy E, Miles L, SanMiguel J, et al. Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis. Leukemia. 2019;: pubmed publisher
	Li Z, Liu S, Xu J, Zhang X, Han D, Liu J, et al. Adult Connective Tissue-Resident Mast Cells Originate from Late Erythro-Myeloid Progenitors. Immunity. 2018;49:640-653.e5 pubmed publisher
	Yamamoto R, Wilkinson A, Ooehara J, Lan X, Lai C, Nakauchi Y, et al. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. Cell Stem Cell. 2018;22:600-607.e4 pubmed publisher
	Collette N, Yee C, Hum N, Murugesh D, Christiansen B, Xie L, et al. Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells. Bone. 2016;88:20-30 pubmed publisher
	Baerenwaldt A, von Burg N, Kreuzaler M, Sitte S, Horvath E, Peter A, et al. Flt3 Ligand Regulates the Development of Innate Lymphoid Cells in Fetal and Adult Mice. J Immunol. 2016;196:2561-71 pubmed publisher
	Singhal P, Sassi S, Lan L, Au P, Halvorsen S, Fukumura D, et al. Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proc Natl Acad Sci U S A. 2016;113:122-7 pubmed publisher

product information

Antigen :

Ly-6A/E

Apps. Abbrev. :

Flow Cytometry

Cat # :

108129

Clone :

Item :

Brilliant Violet 510™ anti-mouse Ly-6A/E (Sca-1)

Isotype :

Rat IgG2a, κ

Other Names :

Sca-1

Size :

125 μL

Price (USD) :

193 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV510

Immunogen :

IL-2-dependent mouse T-cell line (CTL-L)

Application Notes :

The D7 antibody has been reported to induce T cell activation and inhibit TCR-induced IL-2 production. Additional reported applications (for the relevant formats) include: Western blotting 1,2 , immunoprecipitation 1 , in vitro lymphocyte activation 3-6 , induction of redirected lysis 7 , induction of T cell inhibitory signalling 8 , immunofluorescence 9 , and immunohistochemical staining of acetone-fixed frozen sections 13 and Bouin-fixed, paraffin-embedded samples 9 . The two Sca-1 recognizing clones D7 and E13-161.7 have been shown to bind distinct epitopes due to the inability of D7 to block the binding of E13-161.7. 14

more info or order :

BioLegend product webpage