product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse Ly-6A/E (Sca-1)
catalog :
108112
quantity :
100 μg
price :
267 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
D7
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 59
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s3a
Philpott J, Kazimierczyk S, Korgaonkar P, Bordt E, Zois J, Vasudevan C, et al. RXRα Regulates the Development of Resident Tissue Macrophages. Immunohorizons. 2022;6:366-372 pubmed publisher
  • flow cytometry; mouse; fig s4b
Wolock S, Krishnan I, Tenen D, Matkins V, Camacho V, Patel S, et al. Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths. Cell Rep. 2019;28:302-311.e5 pubmed publisher
  • flow cytometry; mouse; fig s6
Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed publisher
  • flow cytometry; mouse; fig s2
Wiesner D, Specht C, Lee C, Smith K, Mukaremera L, Lee S, et al. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015;11:e1004701 pubmed publisher
Feng X, Wang L, Zhou R, Zhou R, Chen L, Peng H, et al. Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging. Nat Commun. 2023;14:3208 pubmed publisher
Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, et al. Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration. Nature. 2023;613:169-178 pubmed publisher
Ding P, Tan Q, Wei Z, Chen Q, Wang C, Qi L, et al. Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation. Bone Res. 2022;10:42 pubmed publisher
Ferreirinha P, Pinheiro R, Landry J, Alves N. Identification of fibroblast progenitors in the developing mouse thymus. Development. 2022;149: pubmed publisher
Leinroth A, Mirando A, Rouse D, Kobayahsi Y, Tata P, Rueckert H, et al. Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations. Cell Rep. 2022;39:110785 pubmed publisher
Li D, Jawale C, Zhou C, Lin L, Trevejo Nunez G, Rahman S, et al. Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity. Cell Host Microbe. 2022;30:530-544.e6 pubmed publisher
Luo H, Zhu G, Eshelman M, Fung T, Lai Q, Wang F, et al. HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia. Mol Cell. 2022;82:833-851.e11 pubmed publisher
Tang Y, Zhu L, Cho J, Li X, Weiss S. Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate. Dev Cell. 2022;57:480-495.e6 pubmed publisher
Alam A, Levanduski E, Denz P, Villavicencio H, Bhatta M, Alhorebi L, et al. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer. Cancer Cell. 2022;40:153-167.e11 pubmed publisher
Nguyen N, Gudmundsson K, Soltis A, Oakley K, Roy K, Han Y, et al. Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation. iScience. 2022;25:103679 pubmed publisher
Tavakol D, Bonini F, Tratwal J, Genta M, Brefie Guth J, Braschler T, et al. Cryogel-based Injectable 3D Microcarrier Co-culture for Support of Hematopoietic Progenitor Niches. Curr Protoc. 2021;1:e275 pubmed publisher
Hinterbrandner M, Rubino V, Stoll C, Forster S, Schnüriger N, Radpour R, et al. Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells. JCI Insight. 2021;6: pubmed publisher
Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, et al. A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Cell Rep. 2021;36:109576 pubmed publisher
Larouche J, Mohiuddin M, Choi J, Ulintz P, Fraczek P, Sabin K, et al. Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging. elife. 2021;10: pubmed publisher
Keerthivasan S, Senbabaoglu Y, Martinez Martin N, Husain B, Verschueren E, Wong A, et al. Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1. Immunity. 2021;54:1511-1526.e8 pubmed publisher
Liu X, Yu J, Xu L, Umphred Wilson K, Peng F, Ding Y, et al. Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β-selection. elife. 2021;10: pubmed publisher
Vogiatzi A, Baltsavia I, Dialynas E, Theodorou V, Zhou Y, Deligianni E, et al. Erf Affects Commitment and Differentiation of Osteoprogenitor Cells in Cranial Sutures via the Retinoic Acid Pathway. Mol Cell Biol. 2021;41:e0014921 pubmed publisher
Rodriguez L, Duchez P, Touya N, Debeissat C, Guitart A, Pasquet J, et al. α-Tocopherol Attenuates Oxidative Phosphorylation of CD34+ Cells, Enhances Their G0 Phase Fraction and Promotes Hematopoietic Stem and Primitive Progenitor Cell Maintenance. Biomolecules. 2021;11: pubmed publisher
Morimoto A, Kikuta J, Nishikawa K, Sudo T, Uenaka M, Furuya M, et al. SLPI is a critical mediator that controls PTH-induced bone formation. Nat Commun. 2021;12:2136 pubmed publisher
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher
Mikami Y, Philips R, Sciumè G, Petermann F, Meylan F, Nagashima H, et al. MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23. Immunity. 2021;54:514-525.e6 pubmed publisher
Endo Y, Baldino K, Li B, Zhang Y, Sakthivel D, MacArthur M, et al. Loss of ARNT in skeletal muscle limits muscle regeneration in aging. FASEB J. 2020;34:16086-16104 pubmed publisher
Ju W, Lu W, Ding L, Bao Y, Hong F, Chen Y, et al. PEDF promotes the repair of bone marrow endothelial cell injury and accelerates hematopoietic reconstruction after bone marrow transplantation. J Biomed Sci. 2020;27:91 pubmed publisher
Markworth J, Brown L, Lim E, Floyd C, Larouche J, Castor Macias J, et al. Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells. JCI Insight. 2020;5: pubmed publisher
Shcherbina A, Larouche J, Fraczek P, Yang B, Brown L, Markworth J, et al. Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis. Cell Rep. 2020;32:107964 pubmed publisher
Shi Y, Kang X, Wang Y, Bian X, He G, Zhou M, et al. Exosomes Derived from Bone Marrow Stromal Cells (BMSCs) Enhance Tendon-Bone Healing by Regulating Macrophage Polarization. Med Sci Monit. 2020;26:e923328 pubmed publisher
Derecka M, Herman J, Cauchy P, Ramamoorthy S, Lupar E, Grün D, et al. EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nat Immunol. 2020;21:261-273 pubmed publisher
Hou M, Han J, Li G, Kwon M, Jiang J, Emani S, et al. Multipotency of mouse trophoblast stem cells. Stem Cell Res Ther. 2020;11:55 pubmed publisher
Hillel Karniel C, Rosen C, Milman Krentsis I, Orgad R, Bachar Lustig E, Shezen E, et al. Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers. Cell Rep. 2020;30:807-819.e4 pubmed publisher
Fukushima T, Tanaka Y, Hamey F, Chang C, Oki T, Asada S, et al. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019;29:4144-4158.e7 pubmed publisher
Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, et al. HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Cancer Cell. 2019;36:645-659.e8 pubmed publisher
Viny A, Bowman R, Liu Y, Lavallée V, Eisman S, Xiao W, et al. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019;25:682-696.e8 pubmed publisher
Yin N, Liu Y, Khoor A, Wang X, Thompson E, Leitges M, et al. Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma. Cancer Cell. 2019;36:156-167.e7 pubmed publisher
Goldstein J, Tabebordbar M, Zhu K, Wang L, Messemer K, Peacker B, et al. In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep. 2019;27:1254-1264.e7 pubmed publisher
Vannini N, Campos V, Girotra M, Trachsel V, Rojas Sutterlin S, Tratwal J, et al. The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance. Cell Stem Cell. 2019;24:405-418.e7 pubmed publisher
Mann M, Mehta A, de Boer C, Kowalczyk M, Lee K, Haldeman P, et al. Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. Cell Rep. 2018;25:2992-3005.e5 pubmed publisher
Karatepe K, Zhu H, Zhang X, Guo R, Kambara H, Loison F, et al. Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow. Stem Cell Reports. 2018;11:1092-1105 pubmed publisher
Hepler C, Shan B, Zhang Q, Henry G, Shao M, Vishvanath L, et al. Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. elife. 2018;7: pubmed publisher
Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, et al. PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Cell Stem Cell. 2018;23:193-209.e5 pubmed publisher
De S, Van Deren D, Peden E, Hockin M, Boulet A, Titen S, et al. Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development. 2018;145: pubmed publisher
Gentek R, Ghigo C, Hoeffel G, Bulle M, Msallam R, Gautier G, et al. Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells. Immunity. 2018;48:1160-1171.e5 pubmed publisher
Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
Cohen I, Zhao D, Bar C, Valdes V, Dauber Decker K, Nguyen M, et al. PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification. Cell Stem Cell. 2018;22:726-739.e7 pubmed publisher
Jungwirth N, Salinas Tejedor L, Jin W, Gudi V, Skripuletz T, Stein V, et al. Mesenchymal Stem Cells Form 3D Clusters Following Intraventricular Transplantation. J Mol Neurosci. 2018;65:60-73 pubmed publisher
Ikram M, Lim Y, Baek S, Jin S, Jeong Y, Kwak J, et al. Co-targeting of Tiam1/Rac1 and Notch ameliorates chemoresistance against doxorubicin in a biomimetic 3D lymphoma model. Oncotarget. 2018;9:2058-2075 pubmed publisher
Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, et al. Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity. Cancer Cell. 2018;33:44-59.e8 pubmed publisher
Wong J, Krueger K, Costa M, Aggarwal A, Du H, McLaughlin T, et al. A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo. Sci Signal. 2016;9:ra103 pubmed
Vannini N, Girotra M, Naveiras O, Nikitin G, Campos V, Giger S, et al. Specification of haematopoietic stem cell fate via modulation of mitochondrial activity. Nat Commun. 2016;7:13125 pubmed publisher
Mizbani A, Luca E, Rushing E, Krutzfeldt J. MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration. Development. 2016;143:4137-4148 pubmed
Liu Q, Chen L, Atkinson J, Claxton D, Wang H. Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model. Cell Death Dis. 2016;7:e2361 pubmed publisher
Singhal P, Sassi S, Lan L, Au P, Halvorsen S, Fukumura D, et al. Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proc Natl Acad Sci U S A. 2016;113:122-7 pubmed publisher
Glotzbach J, Januszyk M, Vial I, Wong V, Gelbard A, Kalisky T, et al. An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells. PLoS ONE. 2011;6:e21211 pubmed publisher
Zhang Y, Kwon S, Yamaguchi T, Cubizolles F, Rousseaux S, Kneissel M, et al. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol. 2008;28:1688-701 pubmed publisher
Bastianutto C, Mian A, Symes J, Mocanu J, Alajez N, Sleep G, et al. Local radiotherapy induces homing of hematopoietic stem cells to the irradiated bone marrow. Cancer Res. 2007;67:10112-6 pubmed
Umland O, Mwangi W, Anderson B, Walker J, Petrie H. The blood contains multiple distinct progenitor populations with clonogenic B and T lineage potential. J Immunol. 2007;178:4147-52 pubmed
product information
Antigen :
Ly-6A/E
Apps. Abbrev. :
FC
Cat # :
108112
Clone :
D7
Item :
APC anti-mouse Ly-6A/E (Sca-1)
Isotype :
Rat IgG2a, κ
Other Names :
Sca-1
Size :
100 μg
Price (USD) :
267 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
IL-2-dependent mouse T-cell line (CTL-L)
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA