Spark YG™ 581 anti-mouse I-A/I-E | BioLegend 107665 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Spark YG™ 581 anti-mouse I-A/I-E

catalog :

107665

quantity :

25 μg

price :

132 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

M5/114.15.2

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...; fig s3b	Yang C, Lei L, Collins J, Briones M, Ma L, Sturdevant G, et al. Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor. Nat Commun. 2021;12:5454 pubmed publisher
flow cytometry; human; loading ...; fig 3b	Clemen R, Freund E, Mrochen D, Miebach L, Schmidt A, Rauch B, et al. Gas Plasma Technology Augments Ovalbumin Immunogenicity and OT-II T Cell Activation Conferring Tumor Protection in Mice. Adv Sci (Weinh). 2021;8:2003395 pubmed publisher
	Williams G, Marmion D, Schonhoff A, Jurkuvenaite A, Won W, Standaert D, et al. T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease. Acta Neuropathol. 2020;139:855-874 pubmed publisher

product information

Antigen :

I-A/I-E

Apps. Abbrev. :

Flow Cytometry

Cat # :

107665

Clone :

M5/114.15.2

Item :

Spark YG™ 581 anti-mouse I-A/I-E

Isotype :

Rat IgG2b, κ

Other Names :

MHC class II

Size :

25 μg

Price (USD) :

132 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

SPKYG_581

Immunogen :

Activated C57BL/6 mouse spleen cells

Application Notes :

The M5/114.15.2 antibody reacts with a polymorphic determinant shared by the I-A b , I-A d , I-A q , I-E d , and I-E k MHC class II alloantigens from mice carrying H-2 p,r,q,b,d,u haplotypes. Clone M5/114.15.2 however does not react wtih I-A f , I-A k , or I-A s MHC class II alloantigens. 1 Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemistry of frozen sections 2,3,6 , in vitro and in vivo blocking of antigen presentation or ligand binding 4-7 , and spatial biology (IBEX) 17,18 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 107655 107656).

more info or order :

BioLegend product webpage