FITC anti-mouse TCR γ/δ | BioLegend 107504 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-mouse TCR γ/δ

catalog :

107504

quantity :

500 μg

price :

275 USD

clonality :

monoclonal

host :

hamsters

conjugate :

FITC

clone name :

UC7-13D5

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s6g	Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. 2019;176:998-1013.e16 pubmed publisher
flow cytometry; mouse; loading ...; fig s2a	Tang A, Choi J, Kotzin J, Yang Y, Hong C, Hobson N, et al. Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature. 2017;545:305-310 pubmed publisher
	Köchl R, Vanes L, Llorian Sopena M, Chakravarty P, Hartweger H, Fountain K, et al. Critical role of WNK1 in MYC-dependent early mouse thymocyte development. elife. 2020;9: pubmed publisher
	Dmitrieva Posocco O, Dzutsev A, Posocco D, Hou V, Yuan W, Thovarai V, et al. Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer. Immunity. 2019;50:166-180.e7 pubmed publisher
	Khosravi N, Caetano M, Cumpian A, Unver N, De la Garza Ramos C, Noble O, et al. IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties. Cancer Immunol Res. 2018;6:788-797 pubmed publisher
	Burton O, Tamayo J, Stranks A, Miller S, Koleoglou K, Weinberg E, et al. IgE promotes type 2 innate lymphoid cells in murine food allergy. Clin Exp Allergy. 2017;: pubmed publisher
	Wu J, Xu L, Han X, Hu H, Qi F, Bai S, et al. Role of γδ T cells in exacerbated airway inflammation during reinfection of neonatally primed mice in adulthood. J Med Virol. 2017;89:2108-2115 pubmed publisher
	Pöllinger B, Junt T, Metzler B, Walker U, Tyndall A, Allard C, et al. Th17 cells, not IL-17+ ?? T cells, drive arthritic bone destruction in mice and humans. J Immunol. 2011;186:2602-12 pubmed publisher
	Frommer F, Waisman A. B cells participate in thymic negative selection of murine auto-reactive CD4+ T cells. PLoS ONE. 2010;5:e15372 pubmed publisher

product information

Antigen :

TCR gamma/delta

Apps. Abbrev. :

Flow Cytometry

Cat # :

107504

Clone :

UC7-13D5

Item :

FITC anti-mouse TCR γ/δ

Isotype :

Armenian Hamster IgG

Other Names :

TCR-γ/δ, γ/δ TCR

Size :

500 μg

Price (USD) :

275 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

FITC

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , in vitro stimulation 1,2,4 . Although several papers have reported in vivo depletion 3, 5,6 , another study found that the effect of the antibody could be the functional blocking of the TCR signaling, rather than cell depletion 7 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 107515 - 107520 ). Though clone UC7-13D5 has been used for the depletion of TCR ?/d T cells in vivo 3-5 , there is a report suggesting that binding of clone UC7-13D5 to the ?/d TCR leads to downregulation of the ?/d TCR, making the ?/d T cells undetectable although they are still present 7 .

more info or order :

BioLegend product webpage