PE anti-mouse 4-1BB Ligand (CD137L) | BioLegend 107105 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse 4-1BB Ligand (CD137L)

catalog :

107105

quantity :

50 μg

price :

90 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

TKS-1

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s15d	Sugiura D, Maruhashi T, Okazaki I, Shimizu K, Maeda T, Takemoto T, et al. Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses. Science. 2019;364:558-566 pubmed publisher
flow cytometry; mouse; fig 1	Lee Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196:3385-97 pubmed publisher
	Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, et al. Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. Sci Rep. 2019;9:6136 pubmed publisher
	Clement M, Marsden M, Stacey M, Abdul Karim J, Gimeno Brias S, Costa Bento D, et al. Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence. PLoS Pathog. 2016;12:e1006050 pubmed publisher
	Martin S, Brown S, Wick D, Nielsen J, Kroeger D, Twumasi Boateng K, et al. Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines. PLoS ONE. 2016;11:e0155189 pubmed publisher
	Nishimoto H, Lee S, Hong H, Potter K, Maeda Yamamoto M, Kinoshita T, et al. Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood. 2005;106:4241-8 pubmed

product information

Antigen :

CD137L

Apps. Abbrev. :

Flow Cytometry

Cat # :

107105

Clone :

TKS-1

Item :

PE anti-mouse 4-1BB Ligand (CD137L)

Isotype :

Rat IgG2a, κ

Other Names :

4-1BBL, CD137L, TNFSF9, 4-1BB Ligand

Size :

50 μg

Price (USD) :

90 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

BALB/c mouse B lymphoma line 2PK-3

Application Notes :

The TKS-1 antibody inhibits binding of soluble 4-1BB to 4-1BBL in vitro . Additional reported applications (for the relevant formats) include: in vitro blocking the binding of 4-1BB to 4-1BBL 1 . For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 107106) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 107104) or biotinylated anti-rat IgG second step (Cat. No. 405402), followed by SAv-PE (Cat. No. 405204)). The LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 107108).

more info or order :

BioLegend product webpage