Alexa Fluor® 488 anti-mouse CD195 (CCR5) | BioLegend 107008 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 488 anti-mouse CD195 (CCR5)

catalog :

107008

quantity :

100 μg

price :

248 USD

clonality :

monoclonal

host :

hamsters

conjugate :

AF488

clone name :

HM-CCR5

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1g	Kastenschmidt J, Coulis G, Farahat P, Pham P, Rios R, Cristal T, et al. A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Rep. 2021;35:108997 pubmed publisher
flow cytometry; mouse; fig s8	Williford J, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell T, et al. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019;5:eaay1357 pubmed publisher
flow cytometry; mouse; fig 3d	Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, et al. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proc Natl Acad Sci U S A. 2017;114:10443-10448 pubmed publisher
flow cytometry; mouse	Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
	Zhang T, Wang Y, Li Q, Lin L, Xu C, Xue Y, et al. Mesenchymal stromal cells equipped by IFNα empower T cells with potent anti-tumor immunity. Oncogene. 2022;41:1866-1881 pubmed publisher
	Katsuyama E, Suárez Fueyo A, Bradley S, Mizui M, Marin A, Mulki L, et al. The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections. Cell Rep. 2020;30:112-123.e4 pubmed publisher
	Rowe R, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W, et al. The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia. J Exp Med. 2019;216:527-538 pubmed publisher
	Lopes N, Charaix J, Cedile O, Serge A, Irla M. Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells. Nat Commun. 2018;9:1262 pubmed publisher
	Kitamura T, Doughty Shenton D, Cassetta L, Fragkogianni S, Brownlie D, Kato Y, et al. Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer. Front Immunol. 2017;8:2004 pubmed publisher
	Tuero I, Venzon D, Robert Guroff M. Mucosal and Systemic Î³Î´+ T Cells Associated with Control of Simian Immunodeficiency Virus Infection. J Immunol. 2016;197:4686-4695 pubmed
	Rabacal W, Pabbisetty S, Hoek K, Cendron D, Guo Y, Maseda D, et al. Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival. Proc Natl Acad Sci U S A. 2016;113:5370-5 pubmed publisher
	Sharma R, Deshmukh U, Zheng L, Fu S, Ju S. X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms. J Immunol. 2009;183:3212-8 pubmed publisher
	Zeiser R, Leveson Gower D, Zambricki E, Kambham N, Beilhack A, Loh J, et al. Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. Blood. 2008;111:453-62 pubmed
	Ishida Y, Kimura A, Kondo T, Hayashi T, Ueno M, Takakura N, et al. Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte infiltration. Am J Pathol. 2007;170:843-54 pubmed
	Mao A, Paharkova Vatchkova V, Hardy J, Miller M, Kovats S. Estrogen selectively promotes the differentiation of dendritic cells with characteristics of Langerhans cells. J Immunol. 2005;175:5146-51 pubmed

product information

Antigen :

CD195

Apps. Abbrev. :

Flow Cytometry

Cat # :

107008

Clone :

HM-CCR5

Item :

Alexa Fluor® 488 anti-mouse CD195 (CCR5)

Isotype :

Armenian Hamster IgG

Other Names :

CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor

Size :

100 μg

Price (USD) :

248 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

A488

Application Notes :

CCR5 is expressed at low density on activated cells. For successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 107006) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 107004) or biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)).

more info or order :

BioLegend product webpage