PE anti-mouse CD178 (FasL) | BioLegend 106605 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse CD178 (FasL)

catalog :

106605

quantity :

50 μg

price :

99 USD

clonality :

monoclonal

host :

hamsters

conjugate :

clone name :

MFL3

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 5b	Xiao F, Ai G, Yan W, Wan X, Luo X, Ning Q. Intrahepatic recruitment of cytotoxic NK cells contributes to autoimmune hepatitis progression. Cell Immunol. 2018;327:13-20 pubmed publisher
	Cannons J, Villarino A, Kapnick S, Preite S, Shih H, Gomez Rodriguez J, et al. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory. Cell Rep. 2021;37:109804 pubmed publisher
	Daneshmandi S, Cassel T, Lin P, Higashi R, Wulf G, Boussiotis V, et al. Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function. Cell Rep. 2021;34:108831 pubmed publisher
	Wallace J, Alosaimi M, Khayat C, Jaber F, Almutairi A, Beaussant Cohen S, et al. ITK deficiency presenting as autoimmune lymphoproliferative syndrome. J Allergy Clin Immunol. 2021;147:743-745.e1 pubmed publisher
	Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher
	Jain A, Irizarry Caro R, McDaniel M, Chawla A, Carroll K, Overcast G, et al. T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity. Nat Immunol. 2020;21:65-74 pubmed publisher
	Castillo Dela Cruz P, Wanek A, Kumar P, An X, Elsegeiny W, Horne W, et al. Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products. Cell Rep. 2019;29:2270-2283.e7 pubmed publisher
	Daglas M, Draxler D, Ho H, McCutcheon F, Galle A, Au A, et al. Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice. Cell Rep. 2019;29:1178-1191.e6 pubmed publisher
	Timilshina M, You Z, Lacher S, Acharya S, Jiang L, Kang Y, et al. Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells. Cell Rep. 2019;27:2948-2961.e7 pubmed publisher
	Schleicher R, Reichenbach F, Kraft P, Kumar A, Lescan M, Todt F, et al. Platelets induce apoptosis via membrane-bound FasL. Blood. 2015;126:1483-93 pubmed publisher
	Huang J, Tsai Y, Chang Y, Wu J, Hung J, Lin K, et al. α-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3. J Immunol. 2014;192:1972-81 pubmed publisher
	Oura R, Arakaki R, Yamada A, Kudo Y, Tanaka E, Hayashi Y, et al. Induction of rapid T cell death and phagocytic activity by Fas-deficient lpr macrophages. J Immunol. 2013;190:578-85 pubmed publisher
	Oida T, Weiner H. Depletion of TGF-? from fetal bovine serum. J Immunol Methods. 2010;362:195-8 pubmed publisher
	Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R. Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells. Blood. 2009;113:6120-7 pubmed publisher

product information

Antigen :

CD178

Apps. Abbrev. :

Flow Cytometry

Cat # :

106605

Clone :

MFL3

Item :

PE anti-mouse CD178 (FasL)

Isotype :

Armenian Hamster IgG

Other Names :

Fas Ligand, FasL, Apo-1 Ligand, CD95 Ligand, TNFSF6

Size :

50 μg

Price (USD) :

99 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

Immunogen :

B6 mouse FasL cDNA-transfected baby hamster kidney (B6 FasL/BHK) cells

Application Notes :

Additional reported applications (for the relevant formats) include: inhibition of the cytotoxicity 1-3 and immunofluorescence microscopy 4 . Fas Ligand is expressed at low density on activated cells. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 106606) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 106604) or biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204). The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 106612).

more info or order :

BioLegend product webpage