product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD178 (FasL)
catalog :
106602
quantity :
500 μg
price :
215 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
MFL3
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 5b
Xiao F, Ai G, Yan W, Wan X, Luo X, Ning Q. Intrahepatic recruitment of cytotoxic NK cells contributes to autoimmune hepatitis progression. Cell Immunol. 2018;327:13-20 pubmed publisher
  • flow cytometry; mouse; fig 3a
Cao G, Wang Q, Li G, Meng Z, Liu H, Tong J, et al. mTOR inhibition potentiates cytotoxicity of V?4 ?? T cells via up-regulating NKG2D and TNF-?. J Leukoc Biol. 2016;100:1181-1189 pubmed
Yuan Y, Zhang Y, Zhao S, Chen J, Yang J, Wang T, et al. Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway. Sci Rep. 2018;8:8837 pubmed publisher
Oura R, Arakaki R, Yamada A, Kudo Y, Tanaka E, Hayashi Y, et al. Induction of rapid T cell death and phagocytic activity by Fas-deficient lpr macrophages. J Immunol. 2013;190:578-85 pubmed publisher
Oida T, Weiner H. Murine CD4 T cells produce a new form of TGF-? as measured by a newly developed TGF-? bioassay. PLoS ONE. 2011;6:e18365 pubmed publisher
Oida T, Weiner H. Depletion of TGF-? from fetal bovine serum. J Immunol Methods. 2010;362:195-8 pubmed publisher
Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R. Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells. Blood. 2009;113:6120-7 pubmed publisher
product information
Antigen :
CD178
Apps. Abbrev. :
Flow Cytometry, Immunofluorescence Microscopy
Cat # :
106602
Clone :
MFL3
Item :
Purified anti-mouse CD178 (FasL)
Isotype :
Armenian Hamster IgG
Other Names :
Fas Ligand, FasL, Apo-1 Ligand, CD95 Ligand, TNFSF6
Size :
500 μg
Price (USD) :
215 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PURE
Immunogen :
B6 mouse FasL cDNA-transfected baby hamster kidney (B6 FasL/BHK) cells
Application Notes :
Additional reported applications (for the relevant formats) include: inhibition of the cytotoxicity 1-3 and immunofluorescence microscopy 4 . Fas Ligand is expressed at low density on activated cells. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 106606) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 106604) or biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)). The Ultra-LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. Nos. 106612).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA