Brilliant Violet 605™ anti-mouse CD152 | BioLegend 106323 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 605™ anti-mouse CD152

catalog :

106323

quantity :

50 μg

price :

292 USD

clonality :

monoclonal

host :

hamsters

conjugate :

BV605

clone name :

UC10-4B9

The same clone is also sold as:

Miltenyi Biotec: 130-102-570, 130-101-924, 130-097-503, 130-102-518
Invitrogen: 14-1522-37, 25-1522-82, 13-1522-85, 25-1522-80, 17-1522-82, 13-1522-82, 61-1522-82, 14-1522-95, 12-1522-81, 12-1522-82, 14-1522-82, 17-1522-80, 12-1522-83

reactivity :

mouse

application :

flow cytometry

citations: 5

Reference
Hinterbrandner M, Rubino V, Stoll C, Forster S, Schnüriger N, Radpour R, et al. Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells. JCI Insight. 2021;6: pubmed publisher
Shi L, Sun Z, Su W, Xu F, Xie D, Zhang Q, et al. Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke. Immunity. 2021;54:1527-1542.e8 pubmed publisher
Li J, Byrne K, Yan F, Yamazoe T, Chen Z, Baslan T, et al. Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy. Immunity. 2018;49:178-193.e7 pubmed publisher
Arce Vargas F, Furness A, Litchfield K, Joshi K, Rosenthal R, Ghorani E, et al. Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies. Cancer Cell. 2018;33:649-663.e4 pubmed publisher
Sugita S, Horie S, Yamada Y, Mochizuki M. Inhibition of B-cell activation by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010;51:5783-8 pubmed publisher

product information

Antigen :

CD152

Apps. Abbrev. :

Flow Cytometry

Cat # :

106323

Clone :

UC10-4B9

Item :

Brilliant Violet 605™ anti-mouse CD152

Isotype :

Armenian Hamster IgG

Other Names :

Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4), Ly-56

Size :

50 μg

Price (USD) :

292 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

BV605

Immunogen :

Mouse CTLA-4-mouse IgG2a fusion protein

Application Notes :

The UC10-4B9 antibody can enhance T cell co-stimulation by blocking CTLA-4 interactions with the B7 co-receptors, favoring CD28 interactions. Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , in vitro stimulation, in vitro and in vivo blocking 1-4 of ligand binding, and as ELISA capture antibody 5 . To reduce non-specific binding to cells bearing Fc-receptors, pre-incubation of cells with anti-mouse CD16/CD32, clone 93 (Cat. No. 101301/101302), is recommended prior to immunofluorescent staining. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 106306) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)). The Ultra LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 106327).