Purified anti-mouse CD123 | BioLegend 106002 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse CD123

catalog :

106002

quantity :

500 μg

price :

229 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

5B11

reactivity :

mouse

application :

flow cytometry, mass cytometry

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
mass cytometry; mouse; loading ...	Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed publisher
flow cytometry; mouse; 1:200	Nishikado H, Fujimura T, Taka H, Mineki R, Ogawa H, Okumura K, et al. Cysteine protease antigens cleave CD123, the Î± subunit of murine IL-3 receptor, on basophils and suppress IL-3-mediated basophil expansion. Biochem Biophys Res Commun. 2015;460:261-6 pubmed publisher
	Khan K, Ponce de León J, Benguigui M, Xu P, Chow A, Cruz Munoz W, et al. Immunostimulatory and anti-tumor metronomic cyclophosphamide regimens assessed in primary orthotopic and metastatic murine breast cancer. NPJ Breast Cancer. 2020;6:29 pubmed publisher
	Huang Z, Zhang W, Yang J, Sun F, Zhou H. Interleukin-3 plays a vital role in hyperoxic acute lung injury in mice via mediating inflammation. BMC Pulm Med. 2018;18:164 pubmed publisher
	Singh K, Piprode V, Mhaske S, Barhanpurkar Naik A, Wani M. IL-3 Differentially Regulates Membrane and Soluble RANKL in Osteoblasts through Metalloproteases and the JAK2/STAT5 Pathway and Improves the RANKL/OPG Ratio in Adult Mice. J Immunol. 2018;200:595-606 pubmed publisher
	Matsuba S, Yabe Wada T, Takeda K, Sato T, Suyama M, Takai T, et al. Identification of Secretory Leukoprotease Inhibitor As an Endogenous Negative Regulator in Allergic Effector Cells. Front Immunol. 2017;8:1538 pubmed publisher

product information

Antigen :

CD123

Apps. Abbrev. :

Cat # :

106002

Clone :

5B11

Item :

Purified anti-mouse CD123

Isotype :

Rat IgG2a, κ

Other Names :

IL-3 Receptor α chain, IL-3Rα

Size :

500 μg

Price (USD) :

229 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

CTLL cells transfected with the mouse IL-3Rα chain

Application Notes :

For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 106006) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 106004) or biotinylated anti-rat IgG second step (Cat. No. 405402), followed by SAv-PE (Cat. No. 405204)). To reduce non-specific binding to cells bearing Fc-receptors, pre-incubation of cells with anti-mouse CD16/CD32, clone 93 (Cat. No. 101301/101302), is recommended prior to immunofluorescent staining.;

more info or order :

BioLegend product webpage