product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-mouse CD86
catalog :
105029
quantity :
25 μg
price :
85 USD
clonality :
monoclonal
host :
rat
conjugate :
APC/Cy7
clone name :
GL-1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4c
Takai A, Kikuchi K, Ichimura M, Tsuneyama K, Moritoki Y, Matsumoto K, et al. Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis. BMC Gastroenterol. 2020;20:46 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 4h
Sang A, Danhorn T, Peterson J, Rankin A, O Connor B, Leach S, et al. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun. 2018;9:3973 pubmed publisher
  • flow cytometry; mouse
Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
Chou Y, Lin C, Dzhagalov I, Chen N, Lin C, Lin C, et al. Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy. Sci Rep. 2020;10:8422 pubmed publisher
Farsakoglu Y, Palomino Segura M, Latino I, Zanaga S, Chatziandreou N, Pizzagalli D, et al. Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner. Cell Rep. 2019;26:2307-2315.e5 pubmed publisher
Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, et al. Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018;49:490-503.e4 pubmed publisher
Wang F, Zhang S, Jeon R, Vuckovic I, Jiang X, Lerman A, et al. Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity. EBioMedicine. 2018;30:303-316 pubmed publisher
Nabet B, Qiu Y, Shabason J, Wu T, Yoon T, Kim B, et al. Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer. Cell. 2017;170:352-366.e13 pubmed publisher
Collinson Pautz M, Slawin K, Levitt J, Spencer D. MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity. PLoS ONE. 2016;11:e0164547 pubmed publisher
Chng S, Kundu P, Dominguez Brauer C, Teo W, Kawajiri K, Fujii Kuriyama Y, et al. Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity. Sci Rep. 2016;6:23820 pubmed publisher
Seki T, Yamamoto M, Taguchi Y, Miyauchi M, Akiyama N, Yamaguchi N, et al. Visualization of RelB expression and activation at the single-cell level during dendritic cell maturation in Relb-Venus knock-in mice. J Biochem. 2015;158:485-95 pubmed publisher
White C, Villarino N, Sloan S, Ganusov V, Schmidt N. Plasmodium suppresses expansion of T cell responses to heterologous infections. J Immunol. 2015;194:697-708 pubmed publisher
Chávez Santoscoy A, Huntimer L, Ramer Tait A, Wannemuehler M, Narasimhan B. Harvesting murine alveolar macrophages and evaluating cellular activation induced by polyanhydride nanoparticles. J Vis Exp. 2012;:e3883 pubmed publisher
Klinger M, Dattilio A, Vizzard M. Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol. 2007;293:R677-85 pubmed
product information
Antigen :
CD86
Apps. Abbrev. :
Flow Cytometry
Cat # :
105029
Clone :
GL-1
Item :
APC/Cyanine7 anti-mouse CD86
Isotype :
Rat IgG2a, κ
Other Names :
B7-2, B70, Ly-58
Size :
25 μg
Price (USD) :
85 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC_CYANINE7
Immunogen :
LPS-activated CBA/Ca mouse splenic B cells
Application Notes :
The GL-1 antibody can block the mixed lymphocyte reaction in vitro and has been shown to inhibit the priming of cytotoxic T lymphocytes in vivo (along with antibodies against B7-1). Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemical staining of acetone-fixed frozen sections 2,6 , immunofluorescence microscopy, and in vivo and in vitro blocking of T cell responses 1-6 . GL-1 is not suitable for immunohistochemical staining of formalin-fixed paraffin sections. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 105051-105056).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA