PerCP anti-mouse CD86 | BioLegend 105025 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP anti-mouse CD86

catalog :

105025

quantity :

25 μg

price :

99 USD

clonality :

monoclonal

host :

rat

conjugate :

PerCP

clone name :

GL-1

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
	Manivasagam S, Williams J, Vollmer L, Bollman B, Bartleson J, Ai S, et al. Targeting IFN-λ Signaling Promotes Recovery from Central Nervous System Autoimmunity. J Immunol. 2022;208:1341-1351 pubmed publisher
	Jiang L, Wang Y, Zhao J, Uehara M, Hou Q, Kasinath V, et al. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020;183:1219-1233.e18 pubmed publisher
	Kawabe T, Yi J, Kawajiri A, Hilligan K, Fang D, Ishii N, et al. Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state. Nat Commun. 2020;11:3366 pubmed publisher
	Xue R, Guo M, Guo L, Liu C, Li S, Luo J, et al. Synthetic Lipopeptide Enhances Protective Immunity Against Helicobacter pylori Infection. Front Immunol. 2019;10:1372 pubmed publisher
	Zwick M, Ulas T, Cho Y, Ried C, Grosse L, Simon C, et al. Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells. Front Immunol. 2019;10:222 pubmed publisher
	Cullis J, Siolas D, Avanzi A, Barui S, Maitra A, Bar Sagi D. Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer. Cancer Immunol Res. 2017;5:182-190 pubmed publisher
	Scheenstra M, De Cuyper I, Branco Madeira F, De Bleser P, Kool M, Meinders M, et al. GATA1-Deficient Dendritic Cells Display Impaired CCL21-Dependent Migration toward Lymph Nodes Due to Reduced Levels of Polysialic Acid. J Immunol. 2016;197:4312-4324 pubmed
	Farkas A, Marvel D, Finn O. Antigen choice determines vaccine-induced generation of immunogenic versus tolerogenic dendritic cells that are marked by differential expression of pancreatic enzymes. J Immunol. 2013;190:3319-27 pubmed publisher
	Vaknin I, Kunis G, Miller O, Butovsky O, Bukshpan S, Beers D, et al. Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. PLoS ONE. 2011;6:e26921 pubmed publisher
	Klinger M, Dattilio A, Vizzard M. Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol. 2007;293:R677-85 pubmed

product information

Antigen :

CD86

Apps. Abbrev. :

Flow Cytometry

Cat # :

105025

Clone :

GL-1

Item :

PerCP anti-mouse CD86

Isotype :

Rat IgG2a, κ

Other Names :

B7-2, B70, Ly-58

Size :

25 μg

Price (USD) :

99 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PERCP

Immunogen :

LPS-activated CBA/Ca mouse splenic B cells

Application Notes :

The GL-1 antibody can block the mixed lymphocyte reaction in vitro and has been shown to inhibit the priming of cytotoxic T lymphocytes in vivo (along with antibodies against B7-1). Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemical staining of acetone-fixed frozen sections 2,6 , immunofluorescence microscopy, and in vivo and in vitro blocking of T cell responses 1-6 . GL-1 is not suitable for immunohistochemical staining of formalin-fixed paraffin sections. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 105051-105056).

more info or order :

BioLegend product webpage