Pacific Blue™ anti-mouse CD86 | BioLegend 105021 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-mouse CD86

catalog :

105021

quantity :

25 μg

price :

85 USD

clonality :

monoclonal

host :

rat

conjugate :

Pacific Blue

clone name :

GL-1

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 2c	Christ A, Günther P, Lauterbach M, Duewell P, Biswas D, Pelka K, et al. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. 2018;172:162-175.e14 pubmed publisher
flow cytometry; mouse	Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
	Ciecko A, Foda B, Barr J, Ramanathan S, Atkinson M, Serreze D, et al. Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation. Cell Rep. 2019;29:3073-3086.e5 pubmed publisher
	Kurup S, Anthony S, Hancox L, Vijay R, Pewe L, Moioffer S, et al. Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria. Cell Host Microbe. 2019;: pubmed publisher
	Ding L, Kim H, Wang Q, Kearns M, Jiang T, Ohlson C, et al. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Rep. 2018;25:2972-2980.e5 pubmed publisher
	Xiao Y, de Paiva C, Yu Z, de Souza R, Li D, Pflugfelder S. Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol. 2018;30:457-470 pubmed publisher
	Noviski M, Mueller J, SATTERTHWAITE A, Garrett Sinha L, Brombacher F, Zikherman J. IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate. elife. 2018;7: pubmed publisher
	Thwe P, Pelgrom L, Cooper R, Beauchamp S, Reisz J, D Alessandro A, et al. Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses. Cell Metab. 2017;26:558-567.e5 pubmed publisher
	Rosendahl Huber S, Luimstra J, van Beek J, Hoppes R, Jacobi R, Hendriks M, et al. Chemical Modification of Influenza CD8+ T-Cell Epitopes Enhances Their Immunogenicity Regardless of Immunodominance. PLoS ONE. 2016;11:e0156462 pubmed publisher
	Rosenheinrich M, Heine W, SchmÃ¼hl C, Pisano F, Dersch P. Natural Killer Cells Mediate Protection against Yersinia pseudotuberculosis in the Mesenteric Lymph Nodes. PLoS ONE. 2015;10:e0136290 pubmed publisher
	Uhlig K, SchÃ¼lke S, Scheuplein V, Malczyk A, Reusch J, Kugelmann S, et al. Lentiviral Protein Transfer Vectors Are an Efficient Vaccine Platform and Induce a Strong Antigen-Specific Cytotoxic T Cell Response. J Virol. 2015;89:9044-60 pubmed publisher
	Joly M, Martin R, Mitra Kaushik S, Phillips L, D Angona A, Richards S, et al. Transient low-dose methotrexate generates B regulatory cells that mediate antigen-specific tolerance to alglucosidase alfa. J Immunol. 2014;193:3947-58 pubmed publisher
	Simones T, Shepherd D. Consequences of AhR activation in steady-state dendritic cells. Toxicol Sci. 2011;119:293-307 pubmed publisher
	Klinger M, Dattilio A, Vizzard M. Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol. 2007;293:R677-85 pubmed

product information

Antigen :

CD86

Apps. Abbrev. :

Flow Cytometry

Cat # :

105021

Clone :

GL-1

Item :

Pacific Blue™ anti-mouse CD86

Isotype :

Rat IgG2a, κ

Other Names :

B7-2, B70, Ly-58

Size :

25 μg

Price (USD) :

85 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

LPS-activated CBA/Ca mouse splenic B cells

Application Notes :

The GL-1 antibody can block the mixed lymphocyte reaction in vitro and has been shown to inhibit the priming of cytotoxic T lymphocytes in vivo (along with antibodies against B7-1). Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemical staining of acetone-fixed frozen sections 2,6 , immunofluorescence microscopy, and in vivo and in vitro blocking of T cell responses 1-6 . GL-1 is not suitable for immunohistochemical staining of formalin-fixed paraffin sections. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 105051-105056).

more info or order :

BioLegend product webpage