PE/Cyanine5 anti-mouse CD86 | BioLegend 105016 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine5 anti-mouse CD86

catalog :

105016

quantity :

100 μg

price :

240 USD

clonality :

monoclonal

host :

rat

conjugate :

PE-Cy5

clone name :

GL-1

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
	Mellal K, Omri S, Mulumba M, Tahiri H, Fortin C, Dorion M, et al. Immunometabolic modulation of retinal inflammation by CD36 ligand. Sci Rep. 2019;9:12903 pubmed publisher
	Kubli S, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, et al. Fcmr regulates mononuclear phagocyte control of anti-tumor immunity. Nat Commun. 2019;10:2678 pubmed publisher
	Chhatbar C, Detje C, Grabski E, Borst K, Spanier J, Ghita L, et al. Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis. Cell Rep. 2018;25:118-129.e4 pubmed publisher
	Zhu Y, Lyapichev K, Lee D, Motti D, Ferraro N, Zhang Y, et al. Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury. J Neurosci. 2017;37:2362-2376 pubmed publisher
	Lim S, Lee J, Koo J, Kang T, Ha S, Choi J. Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells. PLoS ONE. 2016;11:e0155689 pubmed publisher
	Domeier P, Chodisetti S, Soni C, Schell S, Elias M, Wong E, et al. IFN-Î³ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity. J Exp Med. 2016;213:715-32 pubmed publisher
	Wong E, Soni C, Chan A, Domeier P, Shwetank -, Abraham T, et al. B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance. J Immunol. 2015;194:4130-43 pubmed publisher
	Soni C, Wong E, Domeier P, Khan T, Satoh T, Akira S, et al. B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers. J Immunol. 2014;193:4400-14 pubmed publisher
	Shanks K, Nkyimbeng Takwi E, Smith E, Lipsky M, Detolla L, Scott D, et al. Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation. Mol Immunol. 2013;56:480-7 pubmed publisher
	Dane K, Nembrini C, Tomei A, Eby J, O Neil C, Velluto D, et al. Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival. J Control Release. 2011;156:154-60 pubmed publisher
	Klinger M, Dattilio A, Vizzard M. Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol. 2007;293:R677-85 pubmed

product information

Antigen :

CD86

Apps. Abbrev. :

Flow Cytometry

Cat # :

105016

Clone :

GL-1

Item :

PE/Cyanine5 anti-mouse CD86

Isotype :

Rat IgG2a, κ

Other Names :

B7-2, B70, Ly-58

Size :

100 μg

Price (USD) :

240 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PE_CYANINE5

Immunogen :

LPS-activated CBA/Ca mouse splenic B cells

Application Notes :

The GL-1 antibody can block the mixed lymphocyte reaction in vitro and has been shown to inhibit the priming of cytotoxic T lymphocytes in vivo (along with antibodies against B7-1). Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemical staining of acetone-fixed frozen sections 2,6 , immunofluorescence microscopy, and in vivo and in vitro blocking of T cell responses 1-6 . GL-1 is not suitable for immunohistochemical staining of formalin-fixed paraffin sections. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 105051-105056).

more info or order :

BioLegend product webpage