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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-mouse CD86
catalog :
105013
quantity :
25 μg
price :
80 USD
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
GL-1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s1c
McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
  • flow cytometry; mouse
Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
Han P, Hanlon D, Arshad N, Lee J, Tatsuno K, Robinson E, et al. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Sci Adv. 2020;6:eaaz1580 pubmed publisher
Zhang W, Xu L, Park H, Hwang J, Kwak M, Lee P, et al. Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy. Nat Commun. 2020;11:1187 pubmed publisher
Lee C, Jeong H, Lee H, Hong M, Park S, Bae H. Magnolol Attenuates Cisplatin-Induced Muscle Wasting by M2c Macrophage Activation. Front Immunol. 2020;11:77 pubmed publisher
Terashima Y, Toda E, Itakura M, Otsuji M, Yoshinaga S, Okumura K, et al. Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties. Nat Commun. 2020;11:609 pubmed publisher
Olson W, Jakic B, Labi V, Schoeler K, Kind M, Klepsch V, et al. Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21. Cell Rep. 2019;28:2878-2891.e5 pubmed publisher
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, et al. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019;286:3566-3581 pubmed publisher
Perper S, Westmoreland S, Karman J, Twomey R, Seagal J, Wang R, et al. Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus. J Immunol. 2019;: pubmed publisher
Kim C, Baccarella A, Bayat A, Pepper M, Fontana M. FCRL5+ Memory B Cells Exhibit Robust Recall Responses. Cell Rep. 2019;27:1446-1460.e4 pubmed publisher
Limon J, Tang J, Li D, Wolf A, Michelsen K, Funari V, et al. Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models. Cell Host Microbe. 2019;: pubmed publisher
Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, et al. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun. 2019;10:899 pubmed publisher
Chen S, Fang L, Guo W, Zhou Y, Yu G, Li W, et al. Control of Treg cell homeostasis and immune equilibrium by Lkb1 in dendritic cells. Nat Commun. 2018;9:5298 pubmed publisher
Zhang J, Burn C, Young K, Wilson M, Ly K, Budhwani M, et al. Microparticles produced by human papillomavirus type 16 E7-expressing cells impair antigen presenting cell function and the cytotoxic T cell response. Sci Rep. 2018;8:2373 pubmed publisher
Tavazoie M, Pollack I, Tanqueco R, Ostendorf B, Reis B, Gonsalves F, et al. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer. Cell. 2018;172:825-840.e18 pubmed publisher
Oyarce C, Cruz Gómez S, Gálvez Cancino F, Vargas P, Moreau H, Diaz Valdivia N, et al. Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8+ T Cell Responses. Front Immunol. 2017;8:1794 pubmed publisher
Cerina M, Narayanan V, Göbel K, Bittner S, Ruck T, Meuth P, et al. The quality of cortical network function recovery depends on localization and degree of axonal demyelination. Brain Behav Immun. 2017;59:103-117 pubmed publisher
Zamora Chimal J, Fernández Figueroa E, Ruiz Remigio A, Wilkins Rodríguez A, Delgado Domínguez J, Salaiza Suazo N, et al. NKT cell activation by Leishmania mexicana LPG: Description of a novel pathway. Immunobiology. 2017;222:454-462 pubmed publisher
Clement M, Marsden M, Stacey M, Abdul Karim J, Gimeno Brias S, Costa Bento D, et al. Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence. PLoS Pathog. 2016;12:e1006050 pubmed publisher
Fox C, Orr M, Van Hoeven N, Parker S, Mikasa T, Phan T, et al. Adsorption of a synthetic TLR7/8 ligand to aluminum oxyhydroxide for enhanced vaccine adjuvant activity: A formulation approach. J Control Release. 2016;244:98-107 pubmed publisher
Trabucco S, Gerstein R, Zhang H. YY1 Regulates the Germinal Center Reaction by Inhibiting Apoptosis. J Immunol. 2016;197:1699-707 pubmed publisher
Palm A, García Faroldi G, Lundberg M, Pejler G, Kleinau S. Activated mast cells promote differentiation of B cells into effector cells. Sci Rep. 2016;6:20531 pubmed publisher
Toki S, Omary R, Wilson K, Gore J, Peebles R, Pham W. A comprehensive analysis of transfection-assisted delivery of iron oxide nanoparticles to dendritic cells. Nanomedicine. 2013;9:1235-44 pubmed publisher
Lu H, Crawford R, Kaplan B, Kaminski N. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated disruption of the CD40 ligand-induced activation of primary human B cells. Toxicol Appl Pharmacol. 2011;255:251-60 pubmed publisher
Klinger M, Dattilio A, Vizzard M. Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol. 2007;293:R677-85 pubmed
product information
Antigen :
CD86
Apps. Abbrev. :
Flow Cytometry
Cat # :
105013
Clone :
GL-1
Item :
PE/Cyanine7 anti-mouse CD86
Isotype :
Rat IgG2a, κ
Other Names :
B7-2, B70, Ly-58
Size :
25 μg
Price (USD) :
80 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
LPS-activated CBA/Ca mouse splenic B cells
Application Notes :
The GL-1 antibody can block the mixed lymphocyte reaction in vitro and has been shown to inhibit the priming of cytotoxic T lymphocytes in vivo (along with antibodies against B7-1). Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemical staining of acetone-fixed frozen sections 2,6 , immunofluorescence microscopy, and in vivo and in vitro blocking of T cell responses 1-6 . GL-1 is not suitable for immunohistochemical staining of formalin-fixed paraffin sections. The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 105051-105056).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA