product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD80
catalog :
104707
quantity :
50 μg
price :
99 USD
clonality :
monoclonal
host :
hamsters
conjugate :
PE
clone name :
16-10A1
reactivity :
mouse, dogs
application :
flow cytometry
more info or order :
citations: 69
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 3a
Zhang X, Chang A, Zou Y, Xu H, Cui J, Chen Z, et al. Aspirin Attenuates Cardiac Allograft Rejection by Inhibiting the Maturation of Dendritic Cells via the NF-κB Signaling Pathway. Front Pharmacol. 2021;12:706748 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Guo L, Xie H, Zhang Z, Wang Z, Peng S, Niu Y, et al. Fusion Protein Vaccine Based on Ag85B and STEAP1 Induces a Protective Immune Response against Prostate Cancer. Vaccines (Basel). 2021;9: pubmed publisher
  • flow cytometry; mouse; 1:300; loading ...; fig 1a
Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; fig 3b
Humeniuk P, Geiselhart S, Battin C, Webb T, Steinberger P, Paster W, et al. Generation of a Jurkat-based fluorescent reporter cell line to evaluate lipid antigen interaction with the human iNKT cell receptor. Sci Rep. 2019;9:7426 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4g
Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, et al. Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. Sci Rep. 2019;9:6136 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Yao Y, Huang W, Li X, Li X, Qian J, Han H, et al. Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice. Front Immunol. 2018;9:965 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 9b
Papp S, Moderzynski K, Rauch J, Heine L, Kuehl S, Richardt U, et al. Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells. PLoS Negl Trop Dis. 2016;10:e0004935 pubmed publisher
  • flow cytometry; mouse; fig 2j
Sun L, Sun C, Liang Z, Li H, Chen L, Luo H, et al. FSP1(+) fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells. Sci Rep. 2015;5:14871 pubmed publisher
  • flow cytometry; mouse; fig 1
Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed publisher
  • flow cytometry; mouse
White C, Villarino N, Sloan S, Ganusov V, Schmidt N. Plasmodium suppresses expansion of T cell responses to heterologous infections. J Immunol. 2015;194:697-708 pubmed publisher
Piñón Zarate G, Reyes Riquelme F, Sánchez Monroy M, Velasco Torrez M, Martínez Vázquez M, Cárdenas Monroy C, et al. Immunomodulatory Properties of Masticadienonic Acid and 3α-Hydroxy Masticadienoic Acid in Dendritic Cells. Molecules. 2022;27: pubmed publisher
Vogel A, Martin K, Soukup K, Halfmann A, Kerndl M, Brunner J, et al. JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction. Cell Rep. 2022;38:110420 pubmed publisher
Wu G, Murugesan G, Nagala M, McCraw A, Haslam S, Dell A, et al. Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses. Wellcome Open Res. 2021;6:134 pubmed publisher
Izumi G, Nakano H, Nakano K, Whitehead G, Grimm S, Fessler M, et al. CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation. Nat Commun. 2021;12:5029 pubmed publisher
Qi J, Jin F, You Y, Du Y, Liu D, Xu X, et al. Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles. Nat Commun. 2021;12:4755 pubmed publisher
Matundan H, Wang S, Jaggi U, Yu J, Ghiasi H. Suppression of CD80 Expression by ICP22 Affects Herpes Simplex Virus Type 1 Replication and CD8+IFN-γ+ Infiltrates in the Eyes of Infected Mice but Not Latency Reactivation. J Virol. 2021;95:e0103621 pubmed publisher
Schiller M, Azulay Debby H, Boshnak N, Elyahu Y, Korin B, Ben Shaanan T, et al. Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation. Immunity. 2021;54:1022-1036.e8 pubmed publisher
Xu Q, Zhan G, Zhang Z, Yong T, Yang X, Gan L. Manganese porphyrin-based metal-organic framework for synergistic sonodynamic therapy and ferroptosis in hypoxic tumors. Theranostics. 2021;11:1937-1952 pubmed publisher
Wu J, Zhao R, Dai J, Lai G, Khan A, Yu X, et al. Analysis of differential expression of long non‑coding RNAs in exosomes derived from mature and immature dendritic cells. Mol Med Rep. 2021;23: pubmed publisher
Wilhelm J, Quiñones Pérez M, Wang J, Wang X, Basava V, Gao J. Antigen folding improves loading efficiency and antitumor efficacy of PC7A nanoparticle vaccine. J Control Release. 2021;329:353-360 pubmed publisher
Wang X, Ray R, Kratochvil S, Melzi E, Lin Y, Giguere S, et al. Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors. EMBO J. 2021;40:e105926 pubmed publisher
Feng S, Ding H, Liu L, Peng C, Huang Y, Zhong F, et al. Astragalus polysaccharide enhances the immune function of RAW264.7 macrophages via the NF-κB p65/MAPK signaling pathway. Exp Ther Med. 2021;21:20 pubmed publisher
Taddio M, Castro Jaramillo C, Runge P, Blanc A, Keller C, Talip Z, et al. In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET. Mol Imaging Biol. 2021;23:196-207 pubmed publisher
Kadir N, Acosta A, Sarmiento M, Norazmi M. Immunomodulatory Effects of Recombinant Mycobacterium smegmatis Expressing Antigen-85B Epitopes in Infected J774A.1 Murine Macrophages. Pathogens. 2020;9: pubmed publisher
Lin Y, Yang C, Lin C, Hsia T, Chao W, Lin C. Atractylodin ameliorates ovalbumin‑induced asthma in a mouse model and exerts immunomodulatory effects on Th2 immunity and dendritic cell function. Mol Med Rep. 2020;22:4909-4918 pubmed publisher
Ganesan R, Henkels K, Shah K, de la Rosa X, Libreros S, Cheemarla N, et al. D-series Resolvins activate Phospholipase D in phagocytes during inflammation and resolution. FASEB J. 2020;34:15888-15906 pubmed publisher
Xie Z, Peng M, Lu R, Meng X, Liang W, Li Z, et al. Black phosphorus-based photothermal therapy with aCD47-mediated immune checkpoint blockade for enhanced cancer immunotherapy. Light Sci Appl. 2020;9:161 pubmed publisher
Wong R, Belk J, Govero J, Uhrlaub J, Reinartz D, Zhao H, et al. Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Immunity. 2020;53:1078-1094.e7 pubmed publisher
Tsukasaki M, Asano T, Muro R, Huynh N, Komatsu N, Okamoto K, et al. OPG Production Matters Where It Happened. Cell Rep. 2020;32:108124 pubmed publisher
Gruber T, Kremenovic M, Sadozai H, Rombini N, Baeriswyl L, Maibach F, et al. IL-32γ potentiates tumor immunity in melanoma. JCI Insight. 2020;5: pubmed publisher
Wang Y, Hosomi K, Shimoyama A, Yoshii K, Yamaura H, Nagatake T, et al. Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine. Vaccines (Basel). 2020;8: pubmed publisher
Utley A, Chavel C, Lightman S, Holling G, Cooper J, Peng P, et al. CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival. Cell Rep. 2020;31:107815 pubmed publisher
Pilones K, Charpentier M, García Martínez E, Daviaud C, Kraynak J, Aryankalayil J, et al. Radiotherapy Cooperates with IL15 to Induce Antitumor Immune Responses. Cancer Immunol Res. 2020;8:1054-1063 pubmed publisher
He J, Han R, Yu G, Lavin M, Jia Q, Cui P, et al. Epimedium Polysaccharide Ameliorates Benzene-Induced Aplastic Anemia in Mice. Evid Based Complement Alternat Med. 2020;2020:5637507 pubmed publisher
Zhang W, Xu L, Park H, Hwang J, Kwak M, Lee P, et al. Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy. Nat Commun. 2020;11:1187 pubmed publisher
Hong Y, Kim Y, Kim G, Nam G, Kim S, Park Y, et al. Degradation of tumour stromal hyaluronan by small extracellular vesicle-PH20 stimulates CD103+ dendritic cells and in combination with PD-L1 blockade boosts anti-tumour immunity. J Extracell Vesicles. 2019;8:1670893 pubmed publisher
Kashyap A, Fernandez Rodriguez L, Zhao Y, Monaco G, Trefny M, Yoshida N, et al. GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses. Cell Rep. 2019;28:3367-3380.e8 pubmed publisher
Yang C, He B, Zheng Q, Wang D, Qin M, Zhang H, et al. Nano-encapsulated tryptanthrin derivative for combined anticancer therapy via inhibiting indoleamine 2,3-dioxygenase and inducing immunogenic cell death. Nanomedicine (Lond). 2019;14:2423-2440 pubmed publisher
Koyama M, Mukhopadhyay P, Schuster I, Henden A, Hülsdünker J, Varelias A, et al. MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota. Immunity. 2019;51:885-898.e7 pubmed publisher
Kodumudi K, Ramamoorthi G, Snyder C, Basu A, Jia Y, Awshah S, et al. Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in Mediating the Response. Front Immunol. 2019;10:1939 pubmed publisher
Luck H, Khan S, Kim J, Copeland J, Revelo X, Tsai S, et al. Gut-associated IgA+ immune cells regulate obesity-related insulin resistance. Nat Commun. 2019;10:3650 pubmed publisher
Tomay F, Marinelli A, Leoni V, Caccia C, Matros A, Mock H, et al. Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice. J Transl Med. 2019;17:237 pubmed publisher
Liu W, Zou M, Liu T, Zeng J, Li X, Yu W, et al. Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells. Nat Commun. 2019;10:3199 pubmed publisher
Kubli S, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, et al. Fcmr regulates mononuclear phagocyte control of anti-tumor immunity. Nat Commun. 2019;10:2678 pubmed publisher
Lightman S, Utley A, Lee K. Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle. Front Immunol. 2019;10:965 pubmed publisher
Uchil P, Pi R, Haugh K, Ladinsky M, Ventura J, Barrett B, et al. A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus. Cell Host Microbe. 2019;25:87-100.e10 pubmed publisher
Ding L, Kim H, Wang Q, Kearns M, Jiang T, Ohlson C, et al. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Rep. 2018;25:2972-2980.e5 pubmed publisher
Matundan H, Ghiasi H. Herpes Simplex Virus 1 ICP22 Suppresses CD80 Expression by Murine Dendritic Cells. J Virol. 2019;93: pubmed publisher
Hou Y, Liang H, Rao E, Zheng W, Huang X, Deng L, et al. Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Immunity. 2018;49:490-503.e4 pubmed publisher
Rafiq S, YEKU O, Jackson H, Purdon T, van Leeuwen D, Drakes D, et al. Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo. Nat Biotechnol. 2018;36:847-856 pubmed publisher
Takeda Y, Azuma M, Hatsugai R, Fujimoto Y, Hashimoto M, Fukase K, et al. The second and third amino acids of Pam2 lipopeptides are key for the proliferation of cytotoxic T cells. Innate Immun. 2018;24:323-331 pubmed publisher
Bhattacharjee P, Keyel P. Cholesterol-dependent cytolysins impair pro-inflammatory macrophage responses. Sci Rep. 2018;8:6458 pubmed publisher
Xie Z, Wang X, Liu X, Du H, Sun C, Shao X, et al. Adipose-Derived Exosomes Exert Proatherogenic Effects by Regulating Macrophage Foam Cell Formation and Polarization. J Am Heart Assoc. 2018;7: pubmed publisher
Mulder R, Banete A, Seaver K, Basta S. M(IL-4) Tissue Macrophages Support Efficient Interferon-Gamma Production in Antigen-Specific CD8+ T Cells with Reduced Proliferative Capacity. Front Immunol. 2017;8:1629 pubmed publisher
Lin S, Hsieh S, Fan Y, Wei W, Hsiao P, Tsai D, et al. Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance. Autophagy. 2018;14:778-795 pubmed publisher
Ye Y, Wang C, Zhang X, Hu Q, Zhang Y, Liu Q, et al. A melanin-mediated cancer immunotherapy patch. Sci Immunol. 2017;2: pubmed publisher
Zhang F, Xuan Y, Cui J, Liu X, Shao Z, Yu B. Nicorandil modulated macrophages activation and polarization via NF-?b signaling pathway. Mol Immunol. 2017;88:69-78 pubmed publisher
Ma W, Jia Y, Liu Q, Yang Y, Yang J, Zhao Z, et al. Modulation of liver regeneration via myeloid PTEN deficiency. Cell Death Dis. 2017;8:e2827 pubmed publisher
Miura N, Akita H, Tateshita N, Nakamura T, Harashima H. Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects. Mol Ther. 2017;25:1003-1013 pubmed publisher
Sebina I, James K, Soon M, Fogg L, Best S, Labastida Rivera F, et al. IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection. PLoS Pathog. 2016;12:e1005999 pubmed publisher
Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, et al. Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice. PLoS ONE. 2015;10:e0141650 pubmed publisher
Koyama M, Cheong M, Markey K, Gartlan K, Kuns R, Locke K, et al. Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease. J Exp Med. 2015;212:1303-21 pubmed publisher
Nagaoka M, Hatta Y, Kawaoka Y, Malherbe L. Antigen signal strength during priming determines effector CD4 T cell function and antigen sensitivity during influenza virus challenge. J Immunol. 2014;193:2812-20 pubmed publisher
Philipsen L, Engels T, Schilling K, Gurbiel S, Fischer K, Tedford K, et al. Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clusters. Mol Cell Proteomics. 2013;12:2551-67 pubmed publisher
Wong E, Khan T, Mohan C, Rahman Z. The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner. J Immunol. 2012;189:5667-81 pubmed publisher
Jeisy Scott V, Kim J, Davis W, Cao W, Katz J, Sambhara S. TLR7 recognition is dispensable for influenza virus A infection but important for the induction of hemagglutinin-specific antibodies in response to the 2009 pandemic split vaccine in mice. J Virol. 2012;86:10988-98 pubmed
Simmons D, Wearsch P, Canaday D, Meyerson H, Liu Y, Wang Y, et al. Type I IFN drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing. J Immunol. 2012;188:3116-26 pubmed publisher
Marshall N, Galvin K, Corcoran A, Boon L, Higgs R, Mills K. Immunotherapy with PI3K inhibitor and Toll-like receptor agonist induces IFN-?+IL-17+ polyfunctional T cells that mediate rejection of murine tumors. Cancer Res. 2012;72:581-91 pubmed publisher
Rozanski C, Arens R, Carlson L, Nair J, Boise L, Chanan Khan A, et al. Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells. J Exp Med. 2011;208:1435-46 pubmed publisher
product information
Antigen :
CD80
Apps. Abbrev. :
Flow Cytometry
Cat # :
104707
Clone :
16-10A1
Item :
PE anti-mouse CD80
Isotype :
Armenian Hamster IgG
Other Names :
B7-1, B7, Ly-53
Size :
50 μg
Price (USD) :
99 USD
Reactivity :
Mouse, Cross-Reactivity: Dog (Canine)
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PE
Immunogen :
CHO cell line transfected with mouse B7 (CD80)
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 2 , in vitro and in vivo blocking of CTLA-4 Ig to CD80 by blocking costimulation of T cells by activated B cells 2-4 , and immunohistochemical staining of acetone-fixed frozen sections 1,4 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 104747-104752).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA