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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse CD80
catalog :
104705
quantity :
50 μg
price :
60 USD
clonality :
monoclonal
host :
hamsters
conjugate :
FITC
clone name :
16-10A1
reactivity :
mouse, dogs
application :
flow cytometry
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 6b
Cignarella F, Filipello F, Bollman B, Cantoni C, Locca A, Mikesell R, et al. TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis. Acta Neuropathol. 2020;140:513-534 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2h
Findlay E, Currie A, Zhang A, Ovciarikova J, Young L, Stevens H, et al. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. Oncoimmunology. 2019;8:1608106 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4e
Miao Y, Yang H, Levorse J, Yuan S, Polak L, Sribour M, et al. Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells. Cell. 2019;177:1172-1186.e14 pubmed publisher
Cheng Y, Kiene N, Tatarian A, Eix E, Schorey J. Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages. PLoS Pathog. 2020;16:e1008569 pubmed publisher
Lv Z, Zhang P, Li D, Qin M, Nie L, Wang X, et al. CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models. Oncoimmunology. 2020;9:1747688 pubmed publisher
Bode K, Bujupi F, Link C, Hein T, Zimmermann S, Peiris D, et al. Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2. Cell Rep. 2019;29:4435-4446.e9 pubmed publisher
Sivapatham S, Ficht X, Barreto de Albuquerque J, Page N, Merkler D, Stein J. Initial Viral Inoculum Determines Kinapse-and Synapse-Like T Cell Motility in Reactive Lymph Nodes. Front Immunol. 2019;10:2086 pubmed publisher
Cianciaruso C, Beltraminelli T, Duval F, Nassiri S, Hamelin R, Mozes A, et al. Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles. Cell Rep. 2019;27:3062-3080.e11 pubmed publisher
Funk K, Klein R. CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis. J Neuroinflammation. 2019;16:22 pubmed publisher
Snell L, Macleod B, Law J, Osokine I, Elsaesser H, Hezaveh K, et al. CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity. Immunity. 2018;49:678-694.e5 pubmed publisher
Xia Y, Xie Y, Yu Z, Xiao H, Jiang G, Zhou X, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018;175:1059-1073.e21 pubmed publisher
Jiang H, Zhang S, Song T, Guan X, Zhang R, Chen X. Trichostatin a Protects Dendritic Cells Against Oxygen-Glucose Deprivation via the SRSF3/PKM2/Glycolytic Pathway. Front Pharmacol. 2018;9:612 pubmed publisher
Kimura A, Kitajima M, Nishida K, Serada S, Fujimoto M, Naka T, et al. NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation. J Exp Med. 2018;215:2197-2209 pubmed publisher
Sun T, Wang F, Pan W, Wu Q, Wang J, Dai J. An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6. Front Immunol. 2018;9:1245 pubmed publisher
Nechama M, Kwon J, Wei S, Kyi A, Welner R, Ben Dov I, et al. The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation. Nat Commun. 2018;9:1603 pubmed publisher
Porciello N, Grazioli P, Campese A, Kunkl M, Caristi S, Mastrogiovanni M, et al. A non-conserved amino acid variant regulates differential signalling between human and mouse CD28. Nat Commun. 2018;9:1080 pubmed publisher
Ji W, Hu J, Yu X, Zhang L, Liu M, Wang Q. Study on the Inhibitory Effects of Ephedra Aconite Asarum Decoction on LPS-Induced Dendritic Cells. Evid Based Complement Alternat Med. 2017;2017:3272649 pubmed publisher
Oyarce C, Cruz Gómez S, Gálvez Cancino F, Vargas P, Moreau H, Diaz Valdivia N, et al. Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8+ T Cell Responses. Front Immunol. 2017;8:1794 pubmed publisher
Sanchez M, Kolar S, Müller S, Reyes C, Wolf A, Ogawa C, et al. O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection. Cell Host Microbe. 2017;22:543-551.e4 pubmed publisher
Aung L, BALASHOV K. Decreased Dicer expression is linked to increased expression of co-stimulatory molecule CD80 on B cells in multiple sclerosis. Mult Scler. 2015;21:1131-8 pubmed publisher
Li X, Sluijter M, Doorduijn E, Kale S, McFerrin H, Liu Y, et al. Limited density of an antigen presented by RMA-S cells requires B7-1/CD28 signaling to enhance T-cell immunity at the effector phase. PLoS ONE. 2014;9:e108192 pubmed publisher
Tassi I, Claudio E, Wang H, Tang W, Ha H, Saret S, et al. The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity. J Immunol. 2014;193:4303-11 pubmed publisher
Xia S, Wei J, Wang J, Sun H, Zheng W, Li Y, et al. A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells. J Leukoc Biol. 2014;95:733-742 pubmed
Liang Y, Ma S, Zhang Y, Wang Y, Cheng Q, Wu Y, et al. IL-1? and TLR4 signaling are involved in the aggravated murine acute graft-versus-host disease caused by delayed bortezomib administration. J Immunol. 2014;192:1277-85 pubmed publisher
Philipsen L, Engels T, Schilling K, Gurbiel S, Fischer K, Tedford K, et al. Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clusters. Mol Cell Proteomics. 2013;12:2551-67 pubmed publisher
Benhamron S, Reiner I, Zcharia E, Atallah M, Grau A, Vlodavsky I, et al. Dissociation between mature phenotype and impaired transmigration in dendritic cells from heparanase-deficient mice. PLoS ONE. 2012;7:e35602 pubmed publisher
Kis Toth K, Hajdu P, Bacskai I, Szilágyi O, Papp F, Szanto A, et al. Voltage-gated sodium channel Nav1.7 maintains the membrane potential and regulates the activation and chemokine-induced migration of a monocyte-derived dendritic cell subset. J Immunol. 2011;187:1273-80 pubmed publisher
Reiner C, McCullar J, Kow R, Le J, Goodlett D, Nathanson N. RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking. PLoS ONE. 2010;5:e13517 pubmed publisher
Li X, Liu Y, Knight D, Odaka Y, Mathis J, Shi R, et al. Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression. PLoS ONE. 2009;4:e6385 pubmed publisher
product information
Antigen :
CD80
Apps. Abbrev. :
Flow Cytometry
Cat # :
104705
Clone :
16-10A1
Item :
FITC anti-mouse CD80
Isotype :
Armenian Hamster IgG
Other Names :
B7-1, B7, Ly-53
Size :
50 μg
Price (USD) :
60 USD
Reactivity :
Mouse, Cross-Reactivity: Dog (Canine)
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
FITC
Immunogen :
CHO cell line transfected with mouse B7 (CD80)
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation 2 , in vitro and in vivo blocking of CTLA-4 Ig to CD80 by blocking costimulation of T cells by activated B cells 2-4 , and immunohistochemical staining of acetone-fixed frozen sections 1,4 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. Nos. 104747-104752).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA