product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 650™ anti-mouse CD69
catalog :
104541
quantity :
50 μg
price :
328 USD
clonality :
monoclonal
host :
hamsters
conjugate :
BV650
clone name :
H1.2F3
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 6a
Xu P, Xiong W, Lin Y, Fan L, Pan H, Li Y. Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression. Cell Death Dis. 2021;12:779 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2g
Binnewies M, Mujal A, Pollack J, Combes A, Hardison E, Barry K, et al. Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity. Cell. 2019;177:556-571.e16 pubmed publisher
Pankhurst T, Buick K, Lange J, Marshall A, Button K, Palmer O, et al. MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity. Cell Rep. 2023;42:112310 pubmed publisher
Arimoto K, Miyauchi S, Troutman T, Zhang Y, Liu M, Stoner S, et al. Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis. Nat Commun. 2023;14:251 pubmed publisher
Hardman C, Chen Y, Wegrecki M, Ng S, Murren R, Mangat D, et al. CD1a promotes systemic manifestations of skin inflammation. Nat Commun. 2022;13:7535 pubmed publisher
Bajaj R, Rodriguez B, Russell W, Warner A, Diao L, Wang J, et al. Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis. Cell Rep. 2022;40:111429 pubmed publisher
Orvain C, Cauvet A, Prudent A, Guignabert C, Thuillet R, Ottaviani M, et al. Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models. Arthritis Res Ther. 2022;24:13 pubmed publisher
Reyes R, Zhang C, Deng Y, Ji N, Mukherjee N, Padrón A, et al. CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation. Oncoimmunology. 2021;10:2006529 pubmed publisher
Wragg K, Tan H, Kristensen A, Nguyen Robertson C, Kelleher A, Parsons M, et al. High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile. Cell Rep. 2020;31:107773 pubmed publisher
Ruhland M, Roberts E, Cai E, Mujal A, Marchuk K, Beppler C, et al. Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells. Cancer Cell. 2020;37:786-799.e5 pubmed publisher
Khiew S, Jain D, Chen J, Yang J, Yin D, Young J, et al. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. J Clin Invest. 2020;130:3453-3466 pubmed publisher
Ishikawa C, Kawakami H, Uchihara J, Senba M, Mori N. CD69 overexpression by human T-cell leukemia virus type 1 Tax transactivation. Biochim Biophys Acta. 2013;1833:1542-52 pubmed publisher
Jordan J, Woods M, Olano J, Walker D. The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses. Infect Immun. 2008;76:3717-24 pubmed publisher
Epardaud M, Elpek K, Rubinstein M, Yonekura A, Bellemare Pelletier A, Bronson R, et al. Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Res. 2008;68:2972-83 pubmed publisher
Kenna T, Thomas R, Steptoe R. Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses. Blood. 2008;111:2091-100 pubmed
product information
Antigen :
CD69
Apps. Abbrev. :
FC
Cat # :
104541
Clone :
H1.2F3
Item :
Brilliant Violet 650™ anti-mouse CD69
Isotype :
Armenian Hamster IgG
Other Names :
Very Early Activation Antigen (VEA), AIM, EA1, MLR3, gp34/28
Size :
50 μg
Price (USD) :
328 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
BV650
Immunogen :
Mouse dendritic epidermal T cell line Y245
Application Notes :
The H1.2F3 antibody has been reported to augment T cell activation. Additional reported applications (for the relevant formats) include: in vitro T cell and NK cell activation^1-3, immunohistochemistry^4,5, and immunoprecipitation^1.This antibody has been characterized in the literature as containing a lambda light chain.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA