LEAF™ Purified anti-mouse CD62L | BioLegend 104416 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-mouse CD62L

catalog :

104416

quantity :

500 μg

price :

250 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MEL-14

reactivity :

mouse

application :

western blot, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, mass cytometry

citations: 148

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2d	Bekeschus S, Clemen R, Nießner F, Sagwal S, Freund E, Schmidt A. Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion. Adv Sci (Weinh). 2020;7:1903438 pubmed publisher
flow cytometry; mouse; loading ...; fig s18	von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	Zhang S, Liang W, Luo L, Sun S, Wang F. The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology. BMC Biol. 2020;18:29 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Kumar A, Chamoto K, Chowdhury P, Honjo T. Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy. elife. 2020;9: pubmed publisher
flow cytometry; mouse; loading ...; fig 1e, 1j	Chen H, Cong X, Wu C, Wu X, Wang J, Mao K, et al. Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9+ T cells. Sci Adv. 2020;6:eaax4690 pubmed publisher
mass cytometry; mouse; 3.5 ug/ml; loading ...; fig 5d	Guo C, Allen B, Hiam K, Dodd D, Van Treuren W, Higginbottom S, et al. Depletion of microbiome-derived molecules in the host using Clostridium genetics. Science. 2019;366: pubmed publisher
flow cytometry; mouse; loading ...; fig 3	Zhao Y, Yang Q, Jin C, Feng Y, Xie S, Xie H, et al. Changes of CD103-expressing pulmonary CD4+ and CD8+ T cells in S. japonicum infected C57BL/6 mice. BMC Infect Dis. 2019;19:999 pubmed publisher
flow cytometry; mouse; loading ...; fig 2f, s3n	Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
flow cytometry; mouse; loading ...; fig e2a	Strickley J, Messerschmidt J, Awad M, Li T, Hasegawa T, Ha D, et al. Immunity to commensal papillomaviruses protects against skin cancer. Nature. 2019;: pubmed publisher
flow cytometry; mouse; loading ...; fig s1h	Mani V, Bromley S, Aijö T, Mora Buch R, Carrizosa E, Warner R, et al. Migratory DCs activate TGF-β to precondition naïve CD8+ T cells for tissue-resident memory fate. Science. 2019;366: pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Shikama Y, Kurosawa M, Furukawa M, Ishimaru N, Matsushita K. Involvement of adiponectin in age-related increases in tear production in mice. Aging (Albany NY). 2019;11:8329-8346 pubmed publisher
flow cytometry; mouse; loading ...; fig 4	Khanom U, Ohigashi I, Fujimori S, Kondo K, Takada K, Takahama Y. TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8+ T Cells. J Immunol. 2019;: pubmed publisher
flow cytometry; mouse; 1:120; loading ...; fig 1a	Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
flow cytometry; mouse; loading ...; fig ex3b	Khan O, Giles J, McDonald S, Manne S, Ngiow S, Patel K, et al. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion. Nature. 2019;: pubmed publisher
flow cytometry; mouse; loading ...; fig 5a	von Gamm M, Schaub A, Jones A, Wolf C, Behrens G, Lichti J, et al. Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3. J Exp Med. 2019;: pubmed publisher
flow cytometry; mouse; loading ...; fig 4b	Qiu J, Villa M, Sanin D, Buck M, O Sullivan D, Ching R, et al. Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Rep. 2019;27:2063-2074.e5 pubmed publisher
flow cytometry; mouse; loading ...; fig 4c	McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
flow cytometry; mouse; loading ...; fig e1b	Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed publisher
flow cytometry; mouse; loading ...; fig 2a	Vuckovic S, Minnie S, Smith D, Gartlan K, Watkins T, Markey K, et al. Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019;129:106-121 pubmed publisher
flow cytometry; mouse; loading ...; fig s5d	Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	James K, Cosway E, LUCAS B, White A, Parnell S, Carvalho Gaspar M, et al. Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration. J Exp Med. 2018;215:2984-2993 pubmed publisher
flow cytometry; mouse; loading ...; fig 2b, 5c	Klement J, Paschall A, Redd P, Ibrahim M, Lu C, Yang D, et al. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. J Clin Invest. 2018;128:5549-5560 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Tilstra J, Avery L, Menk A, Gordon R, Smita S, Kane L, et al. Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. J Clin Invest. 2018;128:4884-4897 pubmed publisher
flow cytometry; mouse; loading ...; fig 6a	Singh M, Ni M, Sullivan J, Hamerman J, Campbell D. B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation. J Exp Med. 2018;215:2429-2443 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	Gisterå A, Klement M, Polyzos K, Mailer R, Duhlin A, Karlsson M, et al. LDL-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice. Circulation. 2018;: pubmed publisher
flow cytometry; mouse; loading ...; fig s2j	Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science. 2018;360: pubmed publisher
flow cytometry; mouse; loading ...; fig 2e	Dipiazza A, Laniewski N, Rattan A, Topham D, Miller J, Sant A. CD4 T Cell Epitope Specificity and Cytokine Potential Are Preserved as Cells Transition from the Lung Vasculature to Lung Tissue following Influenza Virus Infection. J Virol. 2018;92: pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 4e	Zemmour D, Zilionis R, Kiner E, Klein A, Mathis D, Benoist C. Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR. Nat Immunol. 2018;19:291-301 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Doorduijn E, Sluijter M, Marijt K, Querido B, van der Burg S, van Hall T. T cells specific for a TAP-independent self-peptide remain naïve in tumor-bearing mice and are fully exploitable for therapy. Oncoimmunology. 2018;7:e1382793 pubmed publisher
flow cytometry; mouse; loading ...; fig 5f	Koh A, Miller E, Buenrostro J, Moskowitz D, Wang J, Greenleaf W, et al. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol. 2018;19:162-172 pubmed publisher
flow cytometry; mouse; loading ...; fig 1d	Ibitokou S, Dillon B, Sinha M, Szczesny B, Delgadillo A, Reda Abdelrahman D, et al. Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection. J Immunol. 2018;200:643-656 pubmed publisher
flow cytometry; mouse; loading ...; fig 4c	Ernszt D, Banfai K, Kellermayer Z, Pap A, Lord J, Pongracz J, et al. PPARgamma Deficiency Counteracts Thymic Senescence. Front Immunol. 2017;8:1515 pubmed publisher
flow cytometry; mouse; 1:400; loading ...; fig s3b	Hasan Z, Koizumi S, Sasaki D, Yamada H, Arakaki N, Fujihara Y, et al. JunB is essential for IL-23-dependent pathogenicity of Th17 cells. Nat Commun. 2017;8:15628 pubmed publisher
flow cytometry; mouse; loading ...; fig 7g	Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed publisher
flow cytometry; mouse; loading ...; fig 1c	Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, et al. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017;214:1453-1469 pubmed publisher
flow cytometry; mouse; loading ...; fig 3c	Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	González Pérez G, Lamousé Smith E. Gastrointestinal Microbiome Dysbiosis in Infant Mice Alters Peripheral CD8+ T Cell Receptor Signaling. Front Immunol. 2017;8:265 pubmed publisher
flow cytometry; mouse; fig 5b	Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed publisher
flow cytometry; mouse; loading ...; fig 4b	Ramos G, van den Berg A, Nunes Silva V, Weirather J, Peters L, Burkard M, et al. Myocardial aging as a T-cell-mediated phenomenon. Proc Natl Acad Sci U S A. 2017;114:E2420-E2429 pubmed publisher
flow cytometry; mouse; loading ...; fig s6a	van der Weyden L, Arends M, Campbell A, Bald T, Wardle Jones H, Griggs N, et al. Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature. 2017;541:233-236 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 2b	Morita K, Okamura T, Inoue M, Komai T, Teruya S, Iwasaki Y, et al. Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-Î²3 production. Proc Natl Acad Sci U S A. 2016;113:E8131-E8140 pubmed
flow cytometry; mouse; loading ...	Barin J, Talor M, Schaub J, Diny N, Hou X, Hoyer M, et al. Collaborative Interferon-? and Interleukin-17 Signaling Protects the Oral Mucosa from Staphylococcus aureus. Am J Pathol. 2016;186:2337-52 pubmed publisher
flow cytometry; mouse; 1:300; loading ...; fig 4f	Riedel A, Shorthouse D, Haas L, Hall B, Shields J. Tumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016;17:1118-27 pubmed publisher
flow cytometry; mouse; loading ...	Contreras F, Prado C, Gonzalez H, Franz D, Osorio Barrios F, Osorio F, et al. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity. J Immunol. 2016;196:4143-9 pubmed publisher
flow cytometry; mouse; fig 2	Apostolidis S, RodrÃguez RodrÃguez N, SuÃ¡rez Fueyo A, Dioufa N, Ozcan E, CrispÃn J, et al. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016;17:556-64 pubmed publisher
flow cytometry; mouse; fig 2b	Flach A, Litke T, Strauss J, Haberl M, GÃ³mez C, Reindl M, et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease. Proc Natl Acad Sci U S A. 2016;113:3323-8 pubmed publisher
flow cytometry; mouse; fig s5	Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
flow cytometry; mouse; fig 5	MikyÅ¡kovÃ¡ R, Å tÄ›pÃ¡nek I, IndrovÃ¡ M, BieblovÃ¡ J, Å ÃmovÃ¡ J, TruxovÃ¡ I, et al. Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy. Int J Oncol. 2016;48:953-64 pubmed publisher
flow cytometry; mouse; loading ...	Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed publisher
flow cytometry; mouse; fig 1	Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med. 2015;21:1272-9 pubmed publisher
flow cytometry; mouse; fig s7	McCormack R, de Armas L, Shiratsuchi M, Fiorentino D, Olsson M, Lichtenheld M, et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. elife. 2015;4: pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed publisher
flow cytometry; mouse; fig 2a	Li Y, Shen C, Zhu B, Shi F, Eisen H, Chen J. Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells. J Immunol. 2015;195:1591-8 pubmed publisher
flow cytometry; mouse	Vuillefroy de Silly R, DucimetiÃ¨re L, Yacoub Maroun C, Dietrich P, Derouazi M, Walker P. Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells. Eur J Immunol. 2015;45:2263-75 pubmed publisher
flow cytometry; mouse	Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
western blot; mouse; 1:100; fig 5,6	Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1Î± and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed publisher
flow cytometry; mouse	Huang Y, Clarke F, Karimi M, Roy N, Williamson E, Okumura M, et al. CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest. 2015;125:1019-32 pubmed publisher
flow cytometry; mouse	Yuan X, Dee M, Altman N, Malek T. IL-2RÎ²-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa. J Immunol. 2015;194:1334-46 pubmed publisher
flow cytometry; mouse; fig s2	Skripuletz T, Manzel A, GropengieÃŸer K, SchÃ¤fer N, Gudi V, Singh V, et al. Pivotal role of choline metabolites in remyelination. Brain. 2015;138:398-413 pubmed publisher
flow cytometry; mouse; fig 1	Thueson L, Emmons T, Browning D, Kreitinger J, Shepherd D, Wetzel S. In vitro exposure to the herbicide atrazine inhibits T cell activation, proliferation, and cytokine production and significantly increases the frequency of Foxp3+ regulatory T cells. Toxicol Sci. 2015;143:418-29 pubmed publisher
flow cytometry; mouse	Peters A, Burkett P, Sobel R, Buckley C, Watson S, Bettelli E, et al. Podoplanin negatively regulates CD4+ effector T cell responses. J Clin Invest. 2015;125:129-40 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	McKinstry K, Strutt T, Bautista B, Zhang W, Kuang Y, Cooper A, et al. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014;5:5377 pubmed publisher
flow cytometry; mouse; 1:200	Chatterjee S, Thyagarajan K, Kesarwani P, Song J, Soloshchenko M, Fu J, et al. Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors. Cancer Res. 2014;74:6048-59 pubmed publisher
flow cytometry; mouse	Madireddi S, Eun S, Lee S, Nemčovičová I, Mehta A, Zajonc D, et al. Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies. J Exp Med. 2014;211:1433-48 pubmed publisher
flow cytometry; mouse	Smith N, Wissink E, Wang J, Pinello J, Davenport M, Grimson A, et al. Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life. J Immunol. 2014;193:177-84 pubmed publisher
flow cytometry; mouse	Lee J, Walsh M, Hoehn K, James D, Wherry E, Choi Y. Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity. J Immunol. 2014;192:3190-9 pubmed publisher
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	Ly A, Liao Y, Pietrzak H, Ioannidis L, Sidwell T, Gloury R, et al. Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria. Cell Rep. 2019;29:2257-2269.e6 pubmed publisher
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	Wang Z, Yin W, Zhu L, Li J, Yao Y, Chen F, et al. Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production. Immunity. 2018;49:80-92.e7 pubmed publisher
	Elderman M, Hugenholtz F, Belzer C, Boekschoten M, van Beek A, de Haan B, et al. Sex and strain dependent differences in mucosal immunology and microbiota composition in mice. Biol Sex Differ. 2018;9:26 pubmed publisher
	Sun I, Oh M, Zhao L, Patel C, Arwood M, Xu W, et al. mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells. J Immunol. 2018;201:481-492 pubmed publisher
	Noguchi N, Nakamura R, Hatano S, Yamada H, Sun X, Ohara N, et al. Interleukin-21 Induces Short-Lived Effector CD8+ T Cells but Does Not Inhibit Their Exhaustion after Mycobacterium bovis BCG Infection in Mice. Infect Immun. 2018;86: pubmed publisher
	Andargachew R, Martinez R, Kolawole E, Evavold B. CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection. J Immunol. 2018;201:19-30 pubmed publisher
	García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed publisher
	Verbaro D, Sakurai N, Kim B, Shinkai Y, Egawa T. Cutting Edge: The Histone Methyltransferase G9a Is Required for Silencing of Helper T Lineage-Associated Genes in Proliferating CD8 T Cells. J Immunol. 2018;200:3891-3896 pubmed publisher
	Klann J, Kim S, Remedios K, He Z, Metz P, Lopez J, et al. Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance. J Immunol. 2018;200:4012-4023 pubmed publisher
	Stüve P, Minarrieta L, Erdmann H, Arnold Schrauf C, Swallow M, Guderian M, et al. De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages. Front Immunol. 2018;9:495 pubmed publisher
	Sumida H, Cyster J. G-Protein Coupled Receptor 18 Contributes to Establishment of the CD8 Effector T Cell Compartment. Front Immunol. 2018;9:660 pubmed publisher
	Russell T, Velusamy T, Tseng Y, Tscharke D. Increasing antigen presentation on HSV-1-infected cells increases lesion size but does not alter neural infection or latency. J Gen Virol. 2018;99:682-692 pubmed publisher
	Meyer zu Horste G, Przybylski D, Schramm M, Wang C, Schnell A, Lee Y, et al. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 2018;48:556-569.e7 pubmed publisher
	Sun H, Lagarrigue F, Gingras A, Fan Z, Ley K, Ginsberg M. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018;217:1453-1465 pubmed publisher
	Hollinger M, Giudice V, Cummings N, Rivell G, Zhang H, Kajigaya S, et al. PD-1 deficiency augments bone marrow failure in a minor-histocompatibility antigen mismatch lymphocyte infusion model. Exp Hematol. 2018;62:17-23 pubmed publisher
	Oyarce K, Campos Mora M, Gajardo Carrasco T, Pino Lagos K. Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4+ Foxp3- T Cells into CD4+ Foxp3+ Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival. Front Immunol. 2018;9:112 pubmed publisher
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product information

Antigen :

CD62L

Apps. Abbrev. :

Flow Cytometry, CyTOF®, IHC-F, IP, CMCD, Block

Cat # :

104416

Clone :

MEL-14

Item :

LEAF™ Purified anti-mouse CD62L

Isotype :

Rat IgG2a, κ

Other Names :

L-selectin, LECAM-1, Ly-22, LAM-1, MEL-14

Size :

500 μg

Price (USD) :

250 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

LEAF

Immunogen :

C3H/eb mouse B lymphoma 38C-13

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation 1-3 , complement-dependent cytotoxicity 4 , in vivo and in vitro blocking of adhesion 1-3,5 , and immunohistochemical staining of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections 6 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. Nos. 104457-104462).