product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD49d
catalog :
103701
quantity :
50 μg
price :
83 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
9C10 (MFR4.B)
reactivity :
mouse
application :
neutralization, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Sens C, Altrock E, Rau K, Klemis V, von Au A, Pettera S, et al. An O-Glycosylation of Fibronectin Mediates Hepatic Osteodystrophy Through α4β1 Integrin. J Bone Miner Res. 2017;32:70-81 pubmed publisher
  • blocking or activating experiments; mouse; fig s1
Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes D, Tate T, et al. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nat Biotechnol. 2016;34:738-45 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Wu V, Smith A, You H, Nguyen T, Ferguson R, Taylor M, et al. Plasmacytoid dendritic cell-derived IFNα modulates Th17 differentiation during early Bordetella pertussis infection in mice. Mucosal Immunol. 2016;9:777-86 pubmed publisher
  • flow cytometry; mouse; fig 6
Di C, Lin X, Zhang Y, Zhong W, Yuan Y, Zhou T, et al. Basophil-associated OX40 ligand participates in the initiation of Th2 responses during airway inflammation. J Biol Chem. 2015;290:12523-36 pubmed publisher
Hailemichael Y, Johnson D, Abdel Wahab N, Foo W, Bentebibel S, Daher M, et al. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022;40:509-523.e6 pubmed publisher
Zhao D, Zhang H, Uyar R, Hossain J, Miletic H, Tonn J, et al. Comparing Tumor Cell Invasion and Myeloid Cell Composition in Compatible Primary and Relapsing Glioblastoma. Cancers (Basel). 2021;13: pubmed publisher
Moon H, Min C, Kim G, Kim D, Kim K, Lee S, et al. Crbn modulates calcium influx by regulating Orai1 during efferocytosis. Nat Commun. 2020;11:5489 pubmed publisher
Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed publisher
Hong J, Reynoso G, Andhey P, Swain A, Turner J, Boon A, et al. An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses. Cell Rep Med. 2020;1: pubmed publisher
Wu J, Weisshaar N, Hotz Wagenblatt A, Madi A, Ma S, Mieg A, et al. Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion. Sci Adv. 2020;6:eaba3458 pubmed publisher
Berry C, Liu X, Myles A, Nandi S, Chen Y, Hershberg U, et al. BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells. Cell Rep. 2020;31:107474 pubmed publisher
Flamar A, Klose C, Moeller J, Mahlakõiv T, Bessman N, Zhang W, et al. Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity. Immunity. 2020;52:606-619.e6 pubmed publisher
Steinmann S, Schoedsack M, Heinrich F, Breda P, Ochel A, Tiegs G, et al. Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells. Sci Rep. 2020;10:1071 pubmed publisher
Hays C, Touak G, Bouaboud A, Fouet A, Guignot J, Poyart C, et al. Perinatal hormones favor CC17 group B Streptococcus intestinal translocation through M cells and hypervirulence in neonates. elife. 2019;8: pubmed publisher
Akk A, Springer L, Yang L, Hamilton Burdess S, Lambris J, Yan H, et al. Complement activation on neutrophils initiates endothelial adhesion and extravasation. Mol Immunol. 2019;114:629-642 pubmed publisher
Kolter J, Feuerstein R, Zeis P, Hagemeyer N, Paterson N, d Errico P, et al. A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves. Immunity. 2019;50:1482-1497.e7 pubmed publisher
Cassidy L, Young A, Perez Mancera P, Nimmervoll B, Jaulim A, Chen H, et al. A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo. Autophagy. 2018;14:1256-1266 pubmed publisher
Shin J, Fukuhara A, Onodera T, Kita S, Yokoyama C, Otsuki M, et al. SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes. Diabetes. 2018;67:1068-1078 pubmed publisher
Tritama E, Riani C, Rudiansyah I, Hidayat A, Kharisnaeni S, Retnoningrum D. Evaluation of alum-based adjuvant on the immunogenicity of salmonella enterica serovar typhi conjugates vaccines. Hum Vaccin Immunother. 2018;14:1524-1529 pubmed publisher
Lujan E, Zunder E, Ng Y, Goronzy I, Nolan G, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 2015;521:352-6 pubmed publisher
Lelouard H, Fallet M, de Bovis B, Méresse S, Gorvel J. Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology. 2012;142:592-601.e3 pubmed publisher
Jia W, Li H, He Y. The extracellular matrix protein mindin serves as an integrin ligand and is critical for inflammatory cell recruitment. Blood. 2005;106:3854-9 pubmed
product information
Antigen :
CD49d
Apps. Abbrev. :
FC, Block, IHC-F
Cat # :
103701
Clone :
9C10 (MFR4.B)
Item :
Purified anti-mouse CD49d
Isotype :
Rat IgG2a, κ
Other Names :
α4 integrin, VLA-4 α chain, integrin α4, ITGA4
Size :
50 μg
Price (USD) :
83 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
(C57BL/6 x A/J)F 1 mouse fetal liver mas
Application Notes :
Additional reported applications (for the relevant formats) include: in vitro blocking of cell-cell adhesion and T cell costimulation^1,2, and immunohistochemistry^3 of acetone-fixed frozen sections. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103709 & 103710).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA