Ultra-LEAF™ Purified anti-mouse CD49d | BioLegend 103630 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-mouse CD49d

catalog :

103630

quantity :

1 mg

price :

677 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

R1-2

reactivity :

mouse

application :

neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...	Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
	Reed J, Preston Hurlburt P, Philbrick W, Betancur G, Korah M, LUCAS C, et al. The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. PLoS ONE. 2020;15:e0236921 pubmed publisher

product information

Antigen :

CD49d

Apps. Abbrev. :

FC, IP, Block, IHC-F

Cat # :

103630

Clone :

R1-2

Item :

Ultra-LEAF™ Purified anti-mouse CD49d

Isotype :

Rat IgG2b, κ

Other Names :

α4 integrin, VLA-4 α chain, integrin α4, ITGA4

Size :

1 mg

Price (USD) :

677 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

ULEAF

Immunogen :

AKR/Cum mouse spontaneous T lymphoma line TK1

Application Notes :

The R1-2 antibody has been shown to partially block CD49d mediated interactions and, in combination with the 9C10 (MFR4.B) antibody, completely blocks VCAM-1 binding to VLA-4. Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of cell-cell adhesion and T cell costimulation^1-4, immunoprecipitation^1, and immunohistochemistry of frozen sections^5. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103629 and 103630;).;

more info or order :

BioLegend product webpage