PerCP/Cyanine5.5 anti-mouse CD49d | BioLegend 103619 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP/Cyanine5.5 anti-mouse CD49d

catalog :

103619

quantity :

25 μg

price :

147 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

R1-2

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Reference
Wittner J, Schulz S, Steinmetz T, Berges J, Hauke M, Channell W, et al. Krüppel-like factor 2 controls IgA plasma cell compartmentalization and IgA responses. Mucosal Immunol. 2022;15:668-682 pubmed publisher
Mogilenko D, Shpynov O, Andhey P, Arthur L, Swain A, Esaulova E, et al. Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging. Immunity. 2021;54:99-115.e12 pubmed publisher
Yan J, Pandey S, Barnes B, Turner J, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Rep. 2020;31:107820 pubmed publisher
He W, Holtkamp S, Hergenhan S, Kraus K, De Juan A, Weber J, et al. Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues. Immunity. 2018;49:1175-1190.e7 pubmed publisher
Ritzel R, Crapser J, Patel A, Verma R, Grenier J, Chauhan A, et al. Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury. J Immunol. 2016;196:3318-30 pubmed publisher

product information

Antigen :

CD49d

Apps. Abbrev. :

Cat # :

103619

Clone :

R1-2

Item :

PerCP/Cyanine5.5 anti-mouse CD49d

Isotype :

Rat IgG2b, κ

Other Names :

α4 integrin, VLA-4 α chain, integrin α4, ITGA4

Size :

25 μg

Price (USD) :

147 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PERCP_CYANINE5.5

Immunogen :

AKR/Cum mouse spontaneous T lymphoma line TK1

Application Notes :

The R1-2 antibody has been shown to partially block CD49d mediated interactions and, in combination with the 9C10 (MFR4.B) antibody, completely blocks VCAM-1 binding to VLA-4. Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of cell-cell adhesion and T cell costimulation^1-4, immunoprecipitation^1, and immunohistochemistry of frozen sections^5. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103629 and 103630;).;

more info or order :

BioLegend product webpage